Results 11 to 20 of about 20,494 (215)
Time of Administration of Acute or Chronic Doses of Imipramine Affects its Antidepressant Action in Rats [PDF]
Journal of Circadian Rhythms, 2018 The pathogenesis and therapeutics of depression are linked to the operation of the circadian system. Here, we studied the chronopharmacological action of a tricyclic antidepressant, imipramine. Male adult Wistar–Hannover rats were administered imipramine
Hiroshi Kawai +6 more
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Imipramine inhibits feline infectious peritonitis virus infection by targeting host cholesterol metabolism via NPC1 [PDF]
Antimicrobial Agents and ChemotherapyFeline infectious peritonitis (FIP), a fatal disease caused by FIP virus (FIPV), currently lacks effective vaccines and treatments. Imipramine, a tricyclic antidepressant with known broad-spectrum antiviral properties, was investigated for its efficacy ...
Rui Jing +7 more
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Imipramine solubility-pH profiles: self-aggregation vs. common-ion effect [PDF]
ADMET DMPKBackground and purpose: The pH-dependent solubility of imipramine, a tricyclic antidepressant, and its hydrochloride salt was investigated in phosphate buffers and chloride-containing aqueous media using the pH-ramp shake-flask method.
Marković, Olivera S. +7 more
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Neural Regeneration Research, 2016 Retinal ganglion cell (RGC) degeneration is irreversible in glaucoma and tyrosine kinase receptor B (TrkB)-associated signaling pathways have been implicated in the process.
Ming-lei Han +4 more
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Floppy iris syndrome with oral imipramine: A case series
Indian Journal of Ophthalmology, 2012 Intraoperative floppy iris syndrome (IFIS) has commonly been seen with long-term use of α1-adrenoceptor blocking agents. We observed IFIS in three patients during phacoemulsification due to oral imipramine therapy.
Arvind Gupta, Renuka Srinivasan
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The effect of imipramine on the behavior of albino mice in presence of selenium
Libyan International Medical University Journal, 2016 Introduction: Imipramine, a tricyclic antidepressant used in the treatment of depression, anxiety, and other mental condition. Selenium is useful in managing depression and anxiety.
S Aburawi, S Baayo
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Chronic imipramine treatment-induced changes in acetylcholinesterase (EC 3.1.1.7) activity in discrete rat brain regions [PDF]
Brazilian Journal of Medical and Biological Research, 1997 Cholinergic as well as monoaminergic neurotransmission seems to be involved in the etiology of affective disorders. Chronic treatment with imipramine, a classical antidepressant drug, induces adaptive changes in monoaminergic neurotransmission.
R. Camarini, M.A.C. Benedito
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A case of imipramine-associated immune thrombocytopenia [PDF]
The Turkish Journal of Pediatrics, 2009 Drug-induced immune thrombocytopenia (DITP), excluding heparin-induced thrombocytopenia, is relatively uncommon. It is characterized by drug-dependent antibodies that bind to the platelets and cause their destruction when the responsible drug is ...
Ayşe Aksoy, Erol Erduran, Yusuf Gedik
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Journal of Aziz Fatimah Medical and Dental College, 2022 Objective: To assess the anti-depressant and anxiolytic effect of tramadol as compared to imipramine (approved antidepressant) in acute and chronic doses in rats.
Fiza Soomro +3 more
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PLoS ONE, 2021 We previously reported that treatment with the prototypical antidepressant imipramine induced a dose-dependent reduction of the ingestion of a 10% sucrose solution, due to reduction of the licking burst number, thus suggesting reduced motivation and/or ...
Paolo S D'Aquila, Adriana Galistu
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