Results 31 to 40 of about 5,762 (194)

Smoking and antidepressants pharmacokinetics: a systematic review [PDF]

, 2017
Despite an increasingly recognized relationship between depression and smoking, little is known about how smoking influences antidepressant response and treatment outcomes.
Donato, H, Madeira, N, Oliveira, P, Ribeiro, J   +3 more
core   +1 more source

Dysregulation of Astrocytic ATP/Adenosine Release in the Hippocampus Cause Cognitive and Affective Disorders: Molecular Mechanisms, Diagnosis, and Therapy

MedComm, Volume 6, Issue 5, May 2025.
Reactive astrocytes release various molecules, which play a role in maintaining central nervous system (CNS) homeostasis. (1) Gliotransmitters, such as glutamate, γ‐aminobutyric acid (GABA), ATP, and D‐serine, are secreted by vesicular exocytosis. In addition, astrocytes can also release ATP and glutamate through (2) P2X7Rs, (3) connexin‐43 (Cx43 ...
Peter Illes, Patrizia Rubini, Henning Ulrich, Hai‐Yan Yin, Yong Tang   +4 more
wiley   +1 more source

Antidepressant use during pregnancy and the risk of developing gestational hypertension:A retrospective cohort study [PDF]

, 2018
Background: Prior studies reported that exposure to antidepressants during pregnancy may be associated with gestational hypertension. The aim of this study is to assess the association between the use of antidepressants during pregnancy and the risk of ...
Bos, Jens H, Hak, Eelko, Postma, Maarten J, Schuiling-Veninga, Catharina C M, Ter Heijne, Loes F, Zakiyah, Neily   +5 more
core   +2 more sources

Pharmacological Treatment of Neuropsychiatric Symptoms in Huntington's Disease: A Systematic Review

Movement Disorders Clinical Practice, Volume 12, Issue 4, Page 418-431, April 2025.
ABSTRACT Background Studies focusing on the treatment of neuropsychiatric symptoms (NPS) in Huntington's disease (HD) are scarce and show a wide variation in design, outcome measures and methodological quality. The effectiveness of pharmacological treatment of NPS in HD has not been systematically reviewed so far.
Ruben L. Andriessen, Mayke Oosterloo, Jory Molema, Maud M.J. Daemen, David E.J. Linden, Albert F.G. Leentjens   +5 more
wiley   +1 more source

Comprehensive Analysis Reveals the Potential Diagnostic Value of Biomarkers Associated With Aging and Circadian Rhythm in Knee Osteoarthritis

Orthopaedic Surgery, Volume 17, Issue 3, Page 922-938, March 2025.
This study employed transcriptomic analysis and Mendelian randomization to identify diagnostic and therapeutic biomarkers associated with aging‐circadian rhythm in knee osteoarthritis. Further functional and molecular mechanism analyses were conducted to elucidate their roles in knee osteoarthritis, providing a theoretical basis for clinical diagnosis ...
Hao Li, Yuze Yang, Bo Li, Jiaju Yang, Pengyu Liu, Yuanpeng Gao, Min Zhang, Guangzhi Ning   +7 more
wiley   +1 more source

Contribution of physiological dynamics in predicting major depressive disorder severity

Psychophysiology, Volume 62, Issue 2, February 2025.
Abstract This study aimed to explore the physiological dynamics of cognitive stress in patients with Major Depressive Disorder (MDD) and design a multiparametric model for objectively measuring severity of depression. Physiological signal recordings from 40 MDD patients and 40 healthy controls were collected in a baseline stage, in a stress‐inducing ...
Esther García Pagès, Spyridon Kontaxis, Sara Siddi, Mar Posadas‐de Miguel, Concepción de la Cámara, Maria Luisa Bernal, Thais Castro Ribeiro, Pablo Laguna, Llorenç Badiella, Raquel Bailón, Josep Maria Haro, Jordi Aguiló   +11 more
wiley   +1 more source

A prospective naturalistic study of antidepressant-induced jitteriness/anxiety syndrome

Neuropsychiatric Disease and Treatment, 2014
Tsuyoto Harada, Ken Inada, Kazuo Yamada, Kaoru Sakamoto, Jun Ishigooka Department of Psychiatry, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan Objective: Patients often develop neuropsychiatric symptoms such as anxiety and ...
Harada T, Inada K, Yamada K, Sakamoto K, Ishigooka J   +4 more
doaj  

Effects of selective serotonin reuptake inhibitor treatment on plasma oxytocin and cortisol in major depressive disorder [PDF]

, 2013
Background: Oxytocin is known for its capacity to facilitate social bonding, reduce anxiety and for its actions on the stress hypothalamopituitary adrenal (HPA) axis.
A Levine, AB Emiliano, AD Bocking, AF Pitts, AJ Guastella, Alan J Tilbrook, B Ditzen, C Schule, CA Pedersen, Charlotte Keating, CJ Bell, D Marazziti, DA Barton, DA Slattery, David A Barton, DM Witt, EB Binder, G Gimpl, G Meynen, G Scantamburlo, GA Fava, Gavin W Lambert, H Jorgensen, HM Burke, JM Cyranowski, JS Purba, K Uvnas-Moberg, KJ Parker, KJ Parker, L Van Londen, M Fava, M Heinrichs, M Ising, M Yoshida, ME Keck, MF Juruena, MM Lim, NL Lopez-Duran, PW Gold, R Landgraf, RJ Windle, S Ozsoy, SE Swedo, T Onaka, Tye Dawood, UM Anderberg   +45 more
core   +3 more sources

Use of Hemoadsorption and Continuous Venovenous Hemodialysis With Enhanced Middle Molecule Clearance in Drug‐Induced Rhabdomyolysis

Case Reports in Critical Care, Volume 2025, Issue 1, 2025.
Drug‐induced rhabdomyolysis has become increasingly prevalent due to the rising use of medications such as statins, antidepressants, and antipsychotics. These can lead to muscle cell destruction and the release of myoglobin, potentially causing kidney damage.
Sebastian Hafner, Johannes Reins, Christoph Baader, Florian Balling, Sebastian Eff, Ricardo Jorge Dinis-Oliveira   +5 more
wiley   +1 more source

Intestinal Acid Sphingomyelinase Protects From Severe Pathogen-Driven Colitis [PDF]

, 2019
Inflammatory diseases of the gastrointestinal tract are emerging as a global problem with increased evidence and prevalence in numerous countries. A dysregulated sphingolipid metabolism occurs in patients with ulcerative colitis and is discussed to ...
Becker, Katrin A., Ebel, Jana-Fabienne, Hose, Matthias [u.v.m.], Japtok, Lukasz, Klopfleisch, Robert, Meiners, Jana, Palmieri, Vittoria, Schumacher, Fabian, Yusuf, Ayan Mohamud, Zöller, Julia   +9 more
core   +1 more source