Analise Demografica e Socioeconomica do Uso e do Acesso a Medicamentos Antidepressivos no Brasil [PDF]
Depressive disorders, in addition to causing direct negative impacts on health, are also responsible for imposing substantial costs on society. In relation to the treatment of depression, antidepressants have proven effective, and, to the World Health Organization, access to psychotropic drugs for people with mental illnesses offers a chance of ...
arxiv
TREATMENT OF DEPRESSION IN PATIENTS WITH OSTEOARTHRITIS: THE IMPORTANCE OF AN EARLY DIAGNOSIS AND THE ROLE OF DULOXETINE [PDF]
Background: Osteoarthritis (OA) also called degenerative joint disease is the most common chronic condition of the joints that just in 2004, caused moderate to severe disability in 43.4 million of people.
Agius, Mark, Jesus, Cátia, Jesus, Inês
core +1 more source
Pharmacological treatment of primary insomnia in senior citizens in Spain : a comprehensive analysis [PDF]
The article examines the problem of primary insomnia in older adults in Spain, focusing on its prevalence and health consequences. It highlights that, unlike secondary insomnia, primary insomnia has no identifiable cause and may be related to factors ...
Flores Sáenz, Manuel
core +1 more source
Network reconstruction of platelet metabolism identifies metabolic signature for aspirin resistance. [PDF]
Recently there has not been a systematic, objective assessment of the metabolic capabilities of the human platelet. A manually curated, functionally tested, and validated biochemical reaction network of platelet metabolism, iAT-PLT-636, was reconstructed
Bordbar, Aarash+4 more
core +2 more sources
Antidepressant-like Effects of Neuropeptide SF (NPSF) [PDF]
Neuropeptide SF (NPSF) is a member of RFamide neuropeptides that play diverse roles in central nervous system. Little is know about the effects of NPSF on brain functions. Antidepressant-like effect of NPSF was studied in modified mice FST. NPSF showed the antidepressant-like effects by decreasing the immobility time and increasing the climbing and ...
arxiv
A prospective naturalistic study of antidepressant-induced jitteriness/anxiety syndrome
Tsuyoto Harada, Ken Inada, Kazuo Yamada, Kaoru Sakamoto, Jun Ishigooka Department of Psychiatry, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan Objective: Patients often develop neuropsychiatric symptoms such as anxiety and ...
Harada T+4 more
doaj
Ordering chemical graphs by Sombor indices and its applications [PDF]
Topological indices are a class of numerical invariants that predict certain physical and chemical properties of molecules. Recently, two novel topological indices, named as Sombor index and reduced Sombor index, were introduced by Gutman, defined as $$SO(G)=\sum_{uv\in E(G)}\sqrt{d_{G}^{2}(u)+d_{G}^{2}(v)},$$ $$SO_{red}(G)=\sum_{uv\in E(G)}\sqrt{(d_{G}
arxiv
AutoRVO: Local Navigation with Dynamic Constraints in Dense Heterogeneous Traffic [PDF]
We present a novel algorithm for computing collision-free navigation for heterogeneous road-agents such as cars, tricycles, bicycles, and pedestrians in dense traffic. Our approach currently assumes the positions, shapes, and velocities of all vehicles and pedestrians are known and computes smooth trajectories for each agent by taking into account the ...
arxiv
Pathophysiological concepts of functional dyspepsia and irritable bowel syndrome future pharmacotherapy [PDF]
The functional gastrointestinal diseases (FGIDs) are often noticed disturbances. Functional dyspepsja (FD) is the most frequent FGID of the upper part of the gastrointestinal tract while irritable bowel syndrome (IBS) occurs in the lower gastrointestinal
Dobrek, Łukasz, Thor, Piotr
core
Nonparametric Bayesian Approach to Treatment Ranking in Network Meta-Analysis with Application to Comparisons of Antidepressants [PDF]
Network meta-analysis is a powerful tool to synthesize evidence from independent studies and compare multiple treatments simultaneously. A critical task of performing a network meta-analysis is to offer ranks of all available treatment options for a specific disease outcome. Frequently, the estimated treatment rankings are accompanied by a large amount
arxiv