Results 81 to 90 of about 4,831 (146)

Oral side effects of fluoxetine in patients with depressive disorder: A systematic review. [PDF]

open access: yesMed Oral Patol Oral Cir Bucal
Sarrión Pérez MG   +3 more
europepmc   +1 more source

Effects of Initiating Different Antidepressant Subclasses on Motor Vehicle Crash Risk Among Older Adults With Depression. [PDF]

open access: yesJ Am Geriatr Soc
Khan MA   +8 more
europepmc   +1 more source

Low-dose titrated amitriptyline as second-line treatment for adults with irritable bowel syndrome in primary care: the ATLANTIS RCT.

open access: yesHealth Technol Assess
Wright-Hughes A   +21 more
europepmc   +1 more source

Genetic and Phenotypic Associations With Sustained Antidepressant Use in Major Depressive Disorder.

open access: yesJAMA Psychiatry
Walker A   +14 more
europepmc   +1 more source
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Azetidine derivatives of tricyclic antidepressant agents

Journal of Medicinal Chemistry, 1979
Tricyclic derivatives of azetidine were synthesized and screened for their potential antidepressant activity. The active series had the tricyclic ring attached to position 1 and a basic group in position 3 of the azetidine. The most interesting compounds were comparable to the reference standards for reserpine antagonism in mice, the most active being ...
P, Melloni   +4 more
openaire   +2 more sources

Tricyclic Antidepressants in Obsessive-Compulsive Disorder Antiobsessional or Antidepressant Agents?

The Journal of Nervous and Mental Disease, 1983
The response to tricyclic antidepressants of eight obsessive-compulsive patients was assessed at pretreatment and at 4, 8, and 12 weeks of treatment, with the aim of delineating differential rates of improvement, or desynchrony, between the various symptoms. Change in obsessive-compulsive symptoms paralleled change in depression and anxiety, suggesting
M, Mavissakalian, L, Michelson
openaire   +2 more sources

Antidepressants II: tricyclic agents

2002
Abstract Tricyclic antidepressants (TCA) were first synthesized in the 1940s by chemists looking for drugs to act as sedatives, antihistamines, and anti-parkinsonian drugs (Baldessarini, 1996). Use in depression was first reported in the late 1950s, and hundreds of studies have confirmed their effectiveness in adult populations.
Karl Gundersen, Barbara Geller
openaire   +1 more source

Tricyclic antidepressants in obsessive-compulsive disorder: antiobsessional or antidepressant agents? II

American Journal of Psychiatry, 1985
The authors explored the relationship between the antiobsessional and antidepressant effects of tricyclic drugs in primary obsessive-compulsive disorders. Study 1 consisted of a controlled 12-week trial with clomipramine (N = 7) and placebo (N = 5); study 2 analyzed the pooled data from 15 patients uniformly selected and treated with either ...
M, Mavissakalian   +3 more
openaire   +2 more sources

Antidepressant agents: from tricyclics to serotonin uptake inhibitors

Psychological Medicine, 1998
Background. The number of antidepressant drugs available in the market has grown rapidly in the last few years. The present paper underlines some of the pre-clinical and clinical problems that call close attention from the regulatory authorities when approving new drugs.Methods. We present here a review of the literature.Results.
Garattini S.   +2 more
openaire   +3 more sources

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