Results 81 to 90 of about 4,831 (146)
Oral side effects of fluoxetine in patients with depressive disorder: A systematic review. [PDF]
Sarrión Pérez MG +3 more
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Effects of Initiating Different Antidepressant Subclasses on Motor Vehicle Crash Risk Among Older Adults With Depression. [PDF]
Khan MA +8 more
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Fluoxetine substitution for deprescribing antidepressants: a technical approach. [PDF]
Shapiro B, Cohrs D.
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Genetic and Phenotypic Associations With Sustained Antidepressant Use in Major Depressive Disorder.
Walker A +14 more
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Azetidine derivatives of tricyclic antidepressant agents
Journal of Medicinal Chemistry, 1979Tricyclic derivatives of azetidine were synthesized and screened for their potential antidepressant activity. The active series had the tricyclic ring attached to position 1 and a basic group in position 3 of the azetidine. The most interesting compounds were comparable to the reference standards for reserpine antagonism in mice, the most active being ...
P, Melloni +4 more
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Tricyclic Antidepressants in Obsessive-Compulsive Disorder Antiobsessional or Antidepressant Agents?
The Journal of Nervous and Mental Disease, 1983The response to tricyclic antidepressants of eight obsessive-compulsive patients was assessed at pretreatment and at 4, 8, and 12 weeks of treatment, with the aim of delineating differential rates of improvement, or desynchrony, between the various symptoms. Change in obsessive-compulsive symptoms paralleled change in depression and anxiety, suggesting
M, Mavissakalian, L, Michelson
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Antidepressants II: tricyclic agents
2002Abstract Tricyclic antidepressants (TCA) were first synthesized in the 1940s by chemists looking for drugs to act as sedatives, antihistamines, and anti-parkinsonian drugs (Baldessarini, 1996). Use in depression was first reported in the late 1950s, and hundreds of studies have confirmed their effectiveness in adult populations.
Karl Gundersen, Barbara Geller
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American Journal of Psychiatry, 1985
The authors explored the relationship between the antiobsessional and antidepressant effects of tricyclic drugs in primary obsessive-compulsive disorders. Study 1 consisted of a controlled 12-week trial with clomipramine (N = 7) and placebo (N = 5); study 2 analyzed the pooled data from 15 patients uniformly selected and treated with either ...
M, Mavissakalian +3 more
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The authors explored the relationship between the antiobsessional and antidepressant effects of tricyclic drugs in primary obsessive-compulsive disorders. Study 1 consisted of a controlled 12-week trial with clomipramine (N = 7) and placebo (N = 5); study 2 analyzed the pooled data from 15 patients uniformly selected and treated with either ...
M, Mavissakalian +3 more
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Antidepressant agents: from tricyclics to serotonin uptake inhibitors
Psychological Medicine, 1998Background. The number of antidepressant drugs available in the market has grown rapidly in the last few years. The present paper underlines some of the pre-clinical and clinical problems that call close attention from the regulatory authorities when approving new drugs.Methods. We present here a review of the literature.Results.
Garattini S. +2 more
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