Results 221 to 230 of about 122,773 (309)

Evaluation of the Safety, Efficacy and Pharmacokinetics of BGM0504 in Chinese Adults With Type 2 Diabetes: A Multicentre, Randomised, Controlled and Double‐Blind Phase II Trial

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim This study aimed to evaluate its safety, tolerability, pharmacokinetics, pharmacodynamics and efficacy in Chinese adults with T2DM and to preliminarily compare its efficacy and safety with semaglutide through multiple subcutaneous injections. Materials and Methods In this multicentre, randomised, placebo‐controlled and semaglutide‐positive‐
Ping Jin   +9 more
wiley   +1 more source

Association of Physical Activity With All‐Cause and CVD Mortality Across Metabolic and Obesity Phenotypes

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To examine the independent and joint associations of metabolic status, obesity, and physical activity with all‐cause and cardiovascular disease (CVD) mortality across metabolic–obesity phenotypes. Materials and Methods We analysed 442 666 adults from the Korean National Health Insurance Service health screening cohort (2009–2012 ...
Yunmin Han   +3 more
wiley   +1 more source

Sodium/glucose cotransporters 2 inhibitors but not other antidiabetic drugs improve frailty in older adults with diabetes and heart failure with preserved ejection fraction. [PDF]

open access: yesCardiovasc Res
Mone P   +13 more
europepmc   +1 more source

Identification of Frailty Subtypes in African American Adults With and Without Type 2 Diabetes: A Latent Class Analysis From the Jackson Heart Study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To identify frailty subtypes among African American adults with and without diabetes. Methods This analysis included data from 3979 African American men and women who enrolled in the Jackson Heart Study at baseline (Exam1: 2000–2004). To identify frailty subtypes, we selected 25 age‐related deficits in health and functional outcomes as ...
Felicia R. Simpson   +5 more
wiley   +1 more source

Impact of Time of Injection on the Efficacy and Safety of iGlarLixi Versus IDegAsp in Chinese People With Type 2 Diabetes: Exploratory Analysis of the Soli‐D Study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To compare the efficacy and safety of the fixed‐ratio combination of insulin glargine 100 U/mL plus lixisenatide (iGlarLixi) with premixed insulin degludec plus insulin aspart (IDegAsp) according to the injection time of IDegAsp. Materials and Methods The 24‐week, multicentre, randomised, open‐label Soli‐D study enrolled Chinese adults ...
Xin Li   +8 more
wiley   +1 more source

Timing of Antidiabetic Medication Initiation and Risk of Cardiovascular Events and Mortality.

open access: yesJAMA Netw Open
Ko HY   +13 more
europepmc   +1 more source

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