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Design, Synthesis, Molecular Dynamics, and In Vitro Evaluation of Isatin-Based Quinazoline Derivatives as Potential Antidiabetic Agents. [PDF]
Chem BiodiversJaidka S +4 more
europepmc +1 more source
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Diabesity and antidiabetic drugs
Molecular Aspects of Medicine, 2019The prevalence of "diabesity" - diabetes related to obesity - has increased tremendously over the past few decades because of the global obesity epidemic. Although bariatric surgery is the best treatment option for patients with diabesity, a majority of patients are managed only with antidiabetic drugs for various reasons.
Cornelius Fernandez James +1 more
exaly +3 more sources
Screening for Antidiabetic Activities
, 2013 Screening extracts and drug entities for antidiabetic bioactivity is essentially limited to animal models as the processes leading to hyperglycemia and the complications of diabetes involve more than one organ. Further, in vitro results seldom translate into meaningful in vivo outcomes especially in a disease such as Diabetes Mellitus.
Caccetta, Rima, Al Salami, H.
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Current Diabetes Reviews, 2013
Many studies have demonstrated evidence of the health benefits of natural products. Plant extracts have been tested on a variety of physiological disorders, including diabetes mellitus. Studies have tested aqueous extracts, plant fractions extracts, families of active of compounds, and specific active compounds.
Ali, Berraaouan +2 more
openaire +2 more sources
Many studies have demonstrated evidence of the health benefits of natural products. Plant extracts have been tested on a variety of physiological disorders, including diabetes mellitus. Studies have tested aqueous extracts, plant fractions extracts, families of active of compounds, and specific active compounds.
Ali, Berraaouan +2 more
openaire +2 more sources
Primary Care: Clinics in Office Practice, 1990
Although either insulin or oral hypoglycemics may be used in conjunction with diet and exercise in the management of type II diabetes, drug therapy for type I diabetes involves only insulin. C-peptide levels can be tested to assess whether the patient has remaining pancreatic endocrine function.
openaire +2 more sources
Although either insulin or oral hypoglycemics may be used in conjunction with diet and exercise in the management of type II diabetes, drug therapy for type I diabetes involves only insulin. C-peptide levels can be tested to assess whether the patient has remaining pancreatic endocrine function.
openaire +2 more sources
Antidiabetic Drugs and the Kidney
Current Pharmaceutical Design, 2018Nephropathy is among the most common and most devastating complications of diabetes mellitus. Recent data suggest that there is a multifaceted interaction between the kidney and antidiabetic drugs. Thus, the deterioration of renal function may result in important changes in the pharmacokinetic and pharmacodynamic properties of glucose-lowering ...
Vasilis, Tsimihodimos +3 more
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Annals of Internal Medicine, 1959
Excerpt There is some evidence suggesting that the majority of patients with diabetes have subnormal concentrations of insulin in the plasma, but a hypernormal quantity of insulin has been demonstr...
R H, WILLIAMS +3 more
openaire +2 more sources
Excerpt There is some evidence suggesting that the majority of patients with diabetes have subnormal concentrations of insulin in the plasma, but a hypernormal quantity of insulin has been demonstr...
R H, WILLIAMS +3 more
openaire +2 more sources