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Diabesity and antidiabetic drugs
Molecular Aspects of Medicine, 2019The prevalence of "diabesity" - diabetes related to obesity - has increased tremendously over the past few decades because of the global obesity epidemic. Although bariatric surgery is the best treatment option for patients with diabesity, a majority of patients are managed only with antidiabetic drugs for various reasons.
Joseph M Pappachan +1 more
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Screening for Antidiabetic Activities
, 2013 Screening extracts and drug entities for antidiabetic bioactivity is essentially limited to animal models as the processes leading to hyperglycemia and the complications of diabetes involve more than one organ. Further, in vitro results seldom translate into meaningful in vivo outcomes especially in a disease such as Diabetes Mellitus.
Caccetta, Rima, Al Salami, H.
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Current Diabetes Reviews, 2013
Many studies have demonstrated evidence of the health benefits of natural products. Plant extracts have been tested on a variety of physiological disorders, including diabetes mellitus. Studies have tested aqueous extracts, plant fractions extracts, families of active of compounds, and specific active compounds.
Ali, Berraaouan +2 more
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Many studies have demonstrated evidence of the health benefits of natural products. Plant extracts have been tested on a variety of physiological disorders, including diabetes mellitus. Studies have tested aqueous extracts, plant fractions extracts, families of active of compounds, and specific active compounds.
Ali, Berraaouan +2 more
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Antidiabetic Drugs and the Kidney
Current Pharmaceutical Design, 2018Nephropathy is among the most common and most devastating complications of diabetes mellitus. Recent data suggest that there is a multifaceted interaction between the kidney and antidiabetic drugs. Thus, the deterioration of renal function may result in important changes in the pharmacokinetic and pharmacodynamic properties of glucose-lowering ...
Vasilis, Tsimihodimos +3 more
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Annals of Internal Medicine, 1959
Excerpt There is some evidence suggesting that the majority of patients with diabetes have subnormal concentrations of insulin in the plasma, but a hypernormal quantity of insulin has been demonstr...
R H, WILLIAMS +3 more
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Excerpt There is some evidence suggesting that the majority of patients with diabetes have subnormal concentrations of insulin in the plasma, but a hypernormal quantity of insulin has been demonstr...
R H, WILLIAMS +3 more
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Primary Care: Clinics in Office Practice, 1990
Although either insulin or oral hypoglycemics may be used in conjunction with diet and exercise in the management of type II diabetes, drug therapy for type I diabetes involves only insulin. C-peptide levels can be tested to assess whether the patient has remaining pancreatic endocrine function.
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Although either insulin or oral hypoglycemics may be used in conjunction with diet and exercise in the management of type II diabetes, drug therapy for type I diabetes involves only insulin. C-peptide levels can be tested to assess whether the patient has remaining pancreatic endocrine function.
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Antidiabetic Behavior of Biguanides
Journal of Pharmaceutical Sciences, 1983The existence of active electron pairs on some nitrogen atoms in phenformin hydrochloride is inferred from the presence of a hydrogen catalytic polarographic wave. This finding emphasizes the ability of biguanides to form hydrogen bridges with other molecular species such as amino acids and proteins, as well as to form coordination complexes with zinc ...
F, Vicente-Pedrós +2 more
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Antidiabetic Herbs and Polyherbal Antidiabetic Formulations –An Overview
International Journal of Research in Pharmacy and Allied ScienceDiabetes mellitus—particularly type 2 diabetes (T2DM)—is increasing rapidly in India and poses significant social and economic challenges. Alongside conventional pharmacotherapy, herbal formulations from Ayurveda and traditional medicine are widely used for glycemic management.
M.Y. Mohammad Ismail, Dr. A. B Roge
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Antidiabetic Agents and Lactation
Journal of Human Lactation, 1992If the dose of insulin and adequate carbohydrate intake is ensured, most diabetic mothers taking insulin will be able to breastfeed satisfactorily. Compared to the dose before pregnancy, the required insulin dose probably will be substantially reduced during breastfeeding.
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