Results 41 to 50 of about 5,425 (150)

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth   +5 more
wiley   +1 more source

A Review of Nanoparticle‐Based Astrocyte Modulation in CNS Disorders: Evaluating the Underexplored Potential of Intranasal Delivery

open access: yesNano Select, Volume 7, Issue 1, January 2026.
Nanoparticle‐driven nose‐to‐brain drug delivery offers a noninvasive approach to bypass the blood–brain barrier (BBB) and directly modulate reactive astrocytes in CNS disorders. This review highlights biodegradable nanoparticles for astrocyte modulation, enhancing drug bioavailability, sustained release, and neuroinflammation control.
Senamile M. Dlamini   +3 more
wiley   +1 more source

Role of tolvaptan in the management of hyponatremia in patients with lung and other cancers: current data and future perspectives

open access: yesCancer Management and Research, 2016
Bijin Thajudeen,1 Abdulla K Salahudeen1,2 1Department of Nephrology, Banner University of Arizona Medical Center, 2Department of Nephrology, Southern Arizona Veterans Health Care System, Tucson, AZ, USA Abstract: Hyponatremia is the most frequently ...
Thajudeen B, Salahudeen AK
doaj  

Validation of Surrogates of Urine Osmolality in Population Studies [PDF]

open access: yes, 2017
The importance of vasopressin and/or urine concentration in various kidney, cardiovascular, and metabolic diseases has been emphasized recently. Due to technical constraints, urine osmolality (Uosm), a direct reflect of urinary concentrating activity, is
Bankir, Lise   +7 more
core   +2 more sources

New cases of δ‐aminolevulinic acid dehydratase deficiency: Functional insights into gene variants using an innovative mouse liver model

open access: yesJournal of Internal Medicine, Volume 299, Issue 1, Page 126-142, January 2026.
Abstract Background Dysfunction of δ‐aminolevulinic acid dehydratase (ALAD), the second enzyme involved in heme biosynthesis, leads to two pathologies: genetic and acquired. The genetic form is an ultrarare, severe childhood‐onset disease inherited in an autosomal recessive manner, whereas the acquired form usually affects adults due to enzyme ...
Elena Di Pierro   +22 more
wiley   +1 more source

Aquaporin modulators: a patent review (2010-2015) [PDF]

open access: yes, 2016
Introduction: Since the discovery of aquaporin-1 (AQP1) as a water channel, more than 2,000 articles, reviews and chapters have been published.
Casini, Angela, Soveral, Graça
core   +1 more source

Model of Nocturnal Polyuria in Older Japanese Adults Receiving Enteral Nutrition in Medical Long‐Term Care Hospitals: An Exploratory Cross‐Sectional Study

open access: yesLUTS: Lower Urinary Tract Symptoms, Volume 18, Issue 1, January 2026.
ABSTRACT Objective Nocturnal polyuria (NP) with urinary incontinence increases the risk of sleep disturbance, incontinence‐associated dermatitis, and urinary tract infection. Factors associated with NP in older adults receiving enteral nutrition (EN) have not been clearly identified.
Madoka Takimoto, Tamami Taniguchi
wiley   +1 more source

Fármacos que atuam modulando a ação da vasopressina [PDF]

open access: yes, 2015
Projeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências FarmacêuticasA vasopressina, também é designada por hormona antidiurética (ADH), a nível renal aumenta a
Cardoso, Ana Catarina Santos
core  

Clinical and molecular features of thiazide-induced hyponatremia [PDF]

open access: yes, 2018
Hypertension affects more than 30% of the world’s adult population and thiazide (and thiazide-like) diuretics are amongst the most widely used, effective and least costly treatments available, with all-cause mortality benefits equivalent to ACE ...
Channavajjhala, Sarath K.   +5 more
core   +2 more sources

Short‐ and mid‐term effects of empagliflozin on sodium balance and fluid regulation in chronic heart failure

open access: yesEuropean Journal of Heart Failure, Volume 27, Issue 12, Page 3134-3141, December 2025.
Effects of empagliflozin on sodium and fluid regulation in chronic heart failure (CHF). EF, ejection fraction; NT‐proBNP, N‐terminal pro‐B‐type natriuretic peptide; NYHA, New York Heart Association. Aims Sodium–glucose co‐transporter 2 inhibitors have become a cornerstone in managing chronic heart failure (CHF).
Venera Bytyqi   +11 more
wiley   +1 more source

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