Results 11 to 20 of about 30,801 (283)

Antidotes [PDF]

Trends in Pharmacological Sciences, 2002
This very welcome book on antidotes by Flanagan and Jones from Guy's and St Thomas' NHS Trust is a paperback, but fairly comprehensive text, on antidotes. It includes a chapter on chemical warfare agents by myself and Bob Maynard, on which I will not comment, except to say that, sadly, this chapter may prove a selling point at …
  +6 more sources

Non-Vitamin K Antagonist Oral Anticoagulants in Differentiated Approach to the Use in Cardiological Practice: Literature Review

Український журнал серцево-судинної хірургії, 2023
Non-vitamin K antagonist oral anticoagulants (novel oral anticoagulants, NOACs) are important pharmaceuticals for prevention of stroke and systemic embolism in non-valvular atrial fibrillation patients.
Larysa A. Vozniuk, Olga V. Dzekan, Sergii O. Siromakha   +2 more
doaj   +1 more source

TRADITIONAL USES OF THREATENED ANGIOPTERIS EVECTA (G.FORST.) HOFFM. (MARATTIACEAE) AS AN ANTIDOTE TO SNAKE BITES AND INSECT STINGS BY THE TANGSA TRIBE OF ARUNACHAL PRADESH, INDIA [PDF]

Exploratory Animal and Medical Research, 2023
Angiopteris evecta (G.Forst) Hoffm. (Marattiaceae), an endangered fern, utilized medicinally by several traditional societies across the world. Its use as food is rarely reported in literature.
Pyonim Lungphi, Purnima Laishram, Pinki Gogoi, A. P. Das, Victor Singh Ayam   +4 more
doaj   +1 more source

Synthetic Amphoteric Cryogels as an Antidote against Acute Heavy Metal Poisoning

Molecules, 2021
The effectiveness of an amphoteric cryogel (AAC) as an oral sorbent (enerosorbent) for the treatment of acute poisoning of small animals (rats) with heavy metals (HMs) was studied in in vivo experiments.
Alzhan Z. Baimenov, Ildar R. Fakhradiyev, Dmitriy A. Berillo, Timur Saliev, Sergey V. Mikhalovsky, Talgat S. Nurgozhin, Vassilis J. Inglezakis   +6 more
doaj   +1 more source

Idarucizumab in Dabigatran-Treated Patients with Acute Ischemic Stroke Receiving Thrombolytic Therapy

Medicina, 2022
Background and Objectives: Thrombolytic therapy with recombinant tissue-type plasminogen activator (rt-PA) is used to treat acute ischemic stroke. Dabigatran is a reversible thrombin inhibitor approved for stroke prevention in patients with nonvalvular ...
Ilga Kikule, Alise Baborikina, Iveta Haritoncenko, Guntis Karelis   +3 more
doaj   +1 more source

Optimization of a nicotine degrading enzyme for potential use in treatment of nicotine addiction

BMC Biotechnology, 2019
Background Smoking and tobacco use continue to be the largest preventable causes of death globally. A novel therapeutic approach has recently been proposed: administration of an enzyme that degrades nicotine, the main addictive component of tobacco ...
Thomas Thisted, Zuzana Biesova, Celine Walmacq, Everett Stone, Max Rodnick-Smith, Shaheda S. Ahmed, Stephen K. Horrigan, Bo Van Engelen, Charles Reed, Matthew W. Kalnik   +9 more
doaj   +1 more source

Neutralizing Monoclonal Antibody, mAb 10D8, Is an Effective Detoxicant against Abrin-a Both In Vitro and In Vivo

Toxins, 2022
Abrin is a types II ribosome-inactivating protein (RIP) isolated from Abrus precatorious seeds, which comprises a catalytically active A chain and a lectin-like B chain linked by a disulfide bond.
Zhi Li, Hua Xu, Bo Ma, Li Luo, Lei Guo, Pingping Zhang, Yong Zhao, Lili Wang, Jianwei Xie   +8 more
doaj   +1 more source

The nicotine-degrading enzyme NicA2 reduces nicotine levels in blood, nicotine distribution to brain, and nicotine discrimination and reinforcement in rats

BMC Biotechnology, 2018
Background The bacterial nicotine-degrading enzyme NicA2 isolated from P. putida was studied to assess its potential use in the treatment of tobacco dependence. Results Rats were pretreated with varying i.v.
Paul R. Pentel, Michael D. Raleigh, Mark G. LeSage, Thomas Thisted, Stephen Horrigan, Zuzana Biesova, Matthew W. Kalnik   +6 more
doaj   +1 more source

Statutory, legal, scientific and productive aspects of conditions and prospects of development of antidote therapy in the Russian Federation

Вестник войск РХБ защиты, 2023
The modern period in the development of the world community and the Russian Federation in particular is characterized by the globalization of chemical danger.
V. D. Gladkikh, М. М. Muradov, N. А. Kolosova, I. К. Kasatkin, L. М. Slastilova   +4 more
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source