Results 11 to 20 of about 145,432 (328)
Frontiers in Oncology, 2023 Methotrexate is a commonly used agent in the treatment of many malignancies and rheumatologic/inflammatory diseases. Working by inhibiting dihydrofolate reductase and thereby preventing eventual formation of tetrahydrofolate, methotrexate inhibits ...
Aditya Sharma +3 more
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Effect of Hydroalcoholic Root Extract of Aerva lanata on Acetaminophen Induced Hepatotoxicity in Wistar Rats [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Acute acetaminophen poisoning leads to fulminant hepatic failure and renal tubular damage. N-Acetyl Cysteine (NAC), an antidote for acetaminophen poisoning, carries its own adverse effect profile such as anaphylactoid reactions ...
Parthiban Govindaraju +2 more
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Вестник войск РХБ защиты, 2023 The modern period in the development of the world community and the Russian Federation in particular is characterized by the globalization of chemical danger.
V. D. Gladkikh +4 more
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The Metamorphosis Antidote [PDF]
Neuron, 1999 What if you woke up one morning and your eyes were on the top of your head? You would be confused to see the sky in front of you and would worry that if you took a step to the rear you would smash into the ground. This could never happen unless you lived in a Kafka-esque story and had been transformed into a giant clawed frog.
William A. Harris, Shinichi Nakagawa
openaire +3 more sources
Research and Practice in Thrombosis and Haemostasis, 2021 Background Bivalent thrombin‐binding aptamers (TBAs) have great potential for the treatment of thrombosis because they exhibit high anticoagulant activity, and their complementary single‐stranded DNA (ssDNA) sequences work as an antidote.
Toru Yoshitomi +3 more
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Toxins, 2022 Abrin is a types II ribosome-inactivating protein (RIP) isolated from Abrus precatorious seeds, which comprises a catalytically active A chain and a lectin-like B chain linked by a disulfide bond.
Zhi Li +8 more
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The effect of intravenous lipid emulsion on the outcome of aluminium phosphide poisoning [PDF]
مجله پزشکی دانشگاه علوم پزشکی تبریز, 2023 Background. Due to the high lethality of aluminum phosphide as well as the lack of antidote for its treatment, this study aimed to determine the effect of intravenous lipid emulsion on the outcome of hospitalization in the patients poisoned by rice pill .
Mehdi Torabi +2 more
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Anticoagulants: dose control methods and inhibitors
Акушерство, гинекология и репродукция, 2022 These days, anticoagulants are in great demand. They are used as a prophylaxis for thromboembolic complications in various diseases and conditions in general therapeutic practice, cardiology, neurology, as well as obstetrics to manage high-risk ...
V. O. Bitsadze +9 more
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A neutralizable dimeric anti-thrombin aptamer with potent anticoagulant activity in mice
Molecular Therapy: Nucleic Acids, 2023 Heparin-induced thrombocytopenia (HIT) is a complication caused by administration of the anticoagulant heparin. Although the number of patients with HIT has drastically increased because of coronavirus disease 2019 (COVID-19), the currently used thrombin
Masanobu Nagano +6 more
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Optimization of a nicotine degrading enzyme for potential use in treatment of nicotine addiction
BMC Biotechnology, 2019 Background Smoking and tobacco use continue to be the largest preventable causes of death globally. A novel therapeutic approach has recently been proposed: administration of an enzyme that degrades nicotine, the main addictive component of tobacco ...
Thomas Thisted +9 more
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