Results 21 to 30 of about 64,165 (353)

Cytotoxicity-related effects of imidazolium and chlorinated bispyridinium oximes in SH-SY5Y cells

open access: yesArhiv za Higijenu Rada i Toksikologiju, 2022
Current research has shown that several imidazolium and chlorinated bispyridinium oximes are cytotoxic and activate different mechanisms or types of cell death.
Zandona Antonio   +4 more
doaj   +1 more source

Botulinum Neurotoxins (BoNTs) and Their Biological, Pharmacological, and Toxicological Issues: A Scoping Review

open access: yesApplied Sciences, 2021
Botulinum toxins or neurotoxins (BoNTs) are the most potent neurotoxins known, and are currently extensively studied, not only for their potential lethality, but also for their possible therapeutic and cosmetic uses.
Massimo Corsalini   +10 more
doaj   +1 more source

Erythrocytes as Carriers of Therapeutic Enzymes. [PDF]

open access: yes, 2020
Therapeutic enzymes are administered for the treatment of a wide variety of diseases. They exert their effects through binding with a high affinity and specificity to disease-causing substrates to catalyze their conversion to a non-noxious product, to ...
Bax, BE
core   +1 more source

Availability of Essential Antidotes and the Role of Community Pharmacists in the Management of Acute Poisoning: A Cross-Sectional Study in Ethiopia

open access: yesInquiry: The Journal of Health Care Organization, Provision, and Financing, 2022
Background Morbidity and mortality related to acute poisoning is a major public health issue in both developing and developed countries. Community pharmacists have a crucial role in ensuring drug availability, increasing drug safety, counseling patients,
Zemene Demelash Kifle MSc   +7 more
doaj   +1 more source

How we treat bleeding associated with direct oral anticoagulants [PDF]

open access: yes, 2016
Direct oral anticoagulants are at least as effective as vitamin K antagonists for the prevention and treatment of thromboembolism. Unfortunately, differently from vitamin K antagonists, they have the great drawback of lacking specific antidotes in the ...
Franchini, Massimo   +4 more
core   +1 more source

Autoinjector device for rapid administration of drugs and antidotes in emergency situations and in mass casualty management

open access: yesJournal of International Medical Research, 2020
There are several situations such as medical emergencies and incidents involving mass casualties where drugs and antidotes have to be administered immediately along with other first aid at the site of the event. Self-administration by the affected person
R. Vijayaraghavan
semanticscholar   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

open access: yes, 2022
Hepatology, EarlyView.
Robert J. Fontana   +6 more
wiley   +1 more source

Severe digoxin intoxication: A case report of the use of digoxin-specific Fab antibody fragments

open access: yesZdravniški Vestnik, 2023
Digoxin is a cardiac glycoside that has been used for several decades to treat heart failure and atrial fibrillation. Several doctors prescribe it to their patients, although it is not the first choice for either condition.
Tadej Petreski   +4 more
doaj   +1 more source

Specific Antidotes for Direct Oral Anticoagulants in Life-Threatening Bleeding

open access: yesРациональная фармакотерапия в кардиологии, 2019
Review presents data on medicines from the new group of cardiovascular drugs, direct oral anticoagulants (DOACs) inhibitors, as antidotes for DOAC when stopping life-threatening bleeding.
A. B. Sumarokov   +2 more
doaj   +1 more source

Optimal Resource Allocation for Network Protection Against Spreading Processes [PDF]

open access: yes, 2013
We study the problem of containing spreading processes in arbitrary directed networks by distributing protection resources throughout the nodes of the network.
Enyioha, Chinwendu   +4 more
core   +3 more sources

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