Results 21 to 30 of about 61,140 (309)

Consequences of Opioid Abuse and their Treatments in Persian Medicine: A Review Study [PDF]

Addiction and Health, 2020
Background: Drug addiction is a major health problem for modern human communities. The earliest historicalevidence of opium use can be found in the writings of Theophrastus in the 3rd century BC.
Mohadese Kamali, Haleh Tajadini, Mehrzad Mehrabani, Masoud Moghadari   +3 more
doaj   +1 more source

Effects of multiple doses of montmorillonite, alone and in combination with activated charcoal, on the toxicokinetics of a single dose of digoxin in rats [PDF]

Iranian Journal of Basic Medical Sciences, 2023
Objective(s): A narrow margin between the therapeutic and toxic doses of digoxin can result in an increased incidence of toxicity.  Since digoxin has an enterohepatic cycle, multiple oral doses of absorbents like montmorillonite may be useful in the ...
Fatemeh Heydarian, Mohamad Moshiri, Ali Roohbakhsh, Maryam Akaberi, Atoosa Haghighizadeh, Ameneh Ghadiri, Negar Yeganeh Khorasani, Leila Etemad   +7 more
doaj   +1 more source

The Metamorphosis Antidote [PDF]

Neuron, 1999
What if you woke up one morning and your eyes were on the top of your head? You would be confused to see the sky in front of you and would worry that if you took a step to the rear you would smash into the ground. This could never happen unless you lived in a Kafka-esque story and had been transformed into a giant clawed frog.
William A. Harris, Shinichi Nakagawa
openaire   +3 more sources

Can’t find the antidote: A root cause analysis

Frontiers in Pharmacology, 2022
Background: In a series of cases that came to be recognized as a national methanol outbreak, an incident of delay in allocation and treatment with the antidote fomepizole is described with aim of sharing a learning experience.Method: A team of 16 members
Laila Carolina Abu Esba, Laila Carolina Abu Esba, Laila Carolina Abu Esba, Ghada Mardawi, Ghada Mardawi, Mohammad Al Deeb, Mohammad Al Deeb, Mohammad Al Deeb   +7 more
doaj   +1 more source

Cytotoxicity-related effects of imidazolium and chlorinated bispyridinium oximes in SH-SY5Y cells

Arhiv za Higijenu Rada i Toksikologiju, 2022
Current research has shown that several imidazolium and chlorinated bispyridinium oximes are cytotoxic and activate different mechanisms or types of cell death.
Zandona Antonio, Zorbaz Tamara, Miš Katarina, Pirkmajer Sergej, Katalinić Maja   +4 more
doaj   +1 more source

Design, synthesis, in silico studies and in vitro evaluation of isatin-pyridine oximes hybrids as novel acetylcholinesterase reactivators

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021
Organophosphorus poisoning caused by some pesticides and nerve agents is a life-threating condition that must be swiftly addressed to avoid casualties. Despite the availability of medical countermeasures, the clinically available compounds lack a broad ...
Daniel A. S. Kitagawa, Rafael B. Rodrigues, Thiago N. Silva, Wellington V. dos Santos, Vinicius C. V. da Rocha, Joyce S. F. D. de Almeida, Leandro B. Bernardo, Taynara Carvalho-Silva, Cintia N. Ferreira, Angelo A. T. da Silva, Alessandro B. C. Simas, Eugenie Nepovimova, Kamil Kuča, Tanos C. C. França, Samir F. de A. Cavalcante   +14 more
doaj   +1 more source

Successful Management of Aluminum Phosphide (Celphos) Poisoning With Aspiration Pneumonia: A Case Report [PDF]

Clinical Case Reports
Aluminum phosphide (AlP) poisoning typically has a poor prognosis, but this case report from Nepal demonstrated that prompt hospitalization, aggressive supportive care, including gastric lavage with coconut oil, and careful management of metabolic ...
Rakshya Arun Kandel, Rukma Raj Kafle, Sabin Chaulagain, Chandan Shah, Alok Atreya   +4 more
doaj   +2 more sources

Rational design, synthesis, and evaluation of uncharged, “smart” bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase

Journal of Biological Chemistry, 2020
Organophosphate (OP) intoxications from nerve agent and OP pesticide exposures are managed with pyridinium aldoxime–based therapies whose success rates are currently limited.
L. Górecki, O. Gerlits, Xiaotian Kong, Xiaolin Cheng, D. Blumenthal, P. Taylor, C. Ballatore, A. Kovalevsky, Z. Radić   +8 more
semanticscholar   +1 more source

Intravenous fat emulsion in clinical practice: Nutrient and antidote [PDF]

Vojnosanitetski Pregled, 2015
nema
Putić Vesna, Jović-Stošić Jasmina
doaj   +1 more source

Prevalence and Mortality Incidence of Poisoning Cases in Serdang Hospital

ASM Science Journal, 2020
In Malaysia, there were more than 35,000 poisoning cases enquiries were reported to the poison centre since its establishment from the year 1995 to 2014.
Tan Hooi Leng
doaj   +1 more source