Results 21 to 30 of about 226 (93)

Mechanistic Insights into the Xanthones Present in Mangosteen Fruit (Garcinia mangostana) and Their Applications in Diabetes and Related Complications

open access: yesJournal of Food Biochemistry, Volume 2023, Issue 1, 2023., 2023
Diabetes mellitus is one of the leading public health problems, affecting about 10% of the population. Chronic complications of diabetes cause several human sufferings, including kidney failure, blindness, amputations, stroke, and myocardial infarction.
Rozhan Safaei   +8 more
wiley   +1 more source

A descriptive study of commercial herbal dietary supplements used for dyslipidemia—Sales data and suspected adverse reactions

open access: yesPhytotherapy Research, Volume 36, Issue 6, Page 2583-2604, June 2022., 2022
Abstract Herbal dietary supplements (HDS) used for dyslipidemia represent a category of concern in Italy for suspected adverse reactions (ARs). However, we cannot estimate their safety, as we do not know their commercial profile. Sales data of HDS, and particularly, those used for dyslipidemia, were monitored for 2 years in two pharmacies of Rome ...
Olta Allkanjari   +5 more
wiley   +1 more source

Hyperhomocysteinemia Promotes Cardiac Hypertrophy in Hypertension

open access: yesOxidative Medicine and Cellular Longevity, Volume 2022, Issue 1, 2022., 2022
Hyperhomocysteinemia (HHcy) is positively linked with several cardiovascular diseases; however, its role and underlying mechanisms in pathological cardiac hypertrophy are still unclear. Here, we focused on the effects and underlying mechanisms of HHcy in hypertensive cardiac hypertrophy, one of the most common and typical types of pathological cardiac ...
Yawen Deng   +9 more
wiley   +1 more source

Metabolic Dysfunction in the Regulation of the NLRP3 Inflammasome Activation: A Potential Target for Diabetic Nephropathy

open access: yesJournal of Diabetes Research, Volume 2022, Issue 1, 2022., 2022
Metabolic dysfunction plays a key role in the development of diabetic nephropathy (DN). However, the exact effects and mechanisms are still unclear. The pyrin domain‐containing protein 3 (NLRP3) inflammasome, a member of the nod‐like receptor family, is considered a crucial inflammatory regulator and plays important roles in the progress of DN.
Wenli Zhao   +7 more
wiley   +1 more source

[Retracted] Effects of Torreya grandis Kernel Oil on Lipid Metabolism and Intestinal Flora in C57BL/6J Mice

open access: yesOxidative Medicine and Cellular Longevity, Volume 2022, Issue 1, 2022., 2022
Background. Recent experimental studies have shown that vegetable oil supplementation ameliorates high‐fat diet‐ (HFD‐) induced hyperlipidemia and oxidative stress in mice via modulating hepatic lipid metabolism and the composition of the gut microbiota.
Minghui Xiao   +8 more
wiley   +1 more source

Impact of Phytochemicals on PPAR Receptors: Implications for Disease Treatments

open access: yesPPAR Research, Volume 2022, Issue 1, 2022., 2022
Peroxisome proliferator‐activated receptors (PPARs) are members of the ligand‐dependent nuclear receptor family. PPARs have attracted wide attention as pharmacologic mediators to manage multiple diseases and their underlying signaling targets. They mediate a broad range of specific biological activities and multiple organ toxicity, including cellular ...
Ayesheh Enayati   +5 more
wiley   +1 more source

ANTIDYSLIPIDEMIA AND ANTIOXIDANT ACTIVITY OF ANDROGRAPHOLIDE COMPOUND FROM SAMBILOTO (ANDROGRAPHIS PANICULATA) HERB [PDF]

open access: yes, 2017
Objective: The aim of this study was to observe the antidyslipidemic and antioxidant activity of andrographolide (AND) compound from Sambiloto (Andrographis paniculata) herb.
Susanti, Ni Made Pitri   +4 more
core   +3 more sources

Effect of pioglitazone, as antidiabetic agent, on atheroma regression in type 2 diabetic patients: a systematic review and meta-analysis

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2021
Background Pioglitazone’s role in the induction of atheroma regression in diabetics was suggested by several RCT. The aim of our study was to evaluate this role through a systematic review of all RCT conducted on this subject.
Antoine Fakhry AbdelMassih   +12 more
doaj   +1 more source

Insulin resistance is independently associated with cardiovascular autonomic neuropathy in type 2 diabetes

open access: yesJournal of Diabetes Investigation, Volume 12, Issue 9, Page 1651-1662, September 2021., 2021
Insulin resistance is independently associated with diabetic cardiovascular autonomic neuropathy. The updated homeostasis model assessment of insulin resistance presents to be a highly accurate and cost‐effective indicator for diabetic cardiovascular autonomic neuropathy screening.
Yingshan Liu   +7 more
wiley   +1 more source

Pengaruh Komorbid dan Jenis Terapi terhadap Outcome Kolesterol Total Pasien Dislipidemia

open access: yesJurnal Manajemen dan Pelayanan Farmasi, 2021
Dislipidemia is one of the main risk factors of cardiovascular diseases that contributed more than 25% of death in this world. Hypertension and DM are associated with comorbidity in chronic disease, include of dislipidemia.
Fitri Apriliany   +2 more
doaj   +1 more source

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