Background Various predictive models have been developed which incorporates patient risk factors into the selection of optimal antiemetic therapy, one of which is chemotherapy-induced nausea and vomiting (CINV) risk scoring system developed by ...
Anita D’Souza +8 more
doaj +1 more source
Temsirolimus is a prodrug form of sirolimus (rapamycin). With its analogs (everolimus, ridaforolimus, and rapamycin), it forms a group of anticancer agents that block the activity of one of the two mammalian targets of rapamycin (mTOR) complexes, mTORC1.
Louiza Belkacemi +2 more
doaj +1 more source
Comparative Study of Lidocaine and Palonosetron Pretreatment in Reduction of Propofol Induced Injection Pain [PDF]
Introduction: Propofol is very popular as an induction agent in modern day anaesthesia because of its favourable pharmacodynamics and fewer side effects. Any pain pre or post-anaesthesia leads to patient dissatisfaction.
Suruchi Ambasta, Swagat Mahapatra
doaj +1 more source
Comparative Study of Ondansetron and Palonosetron for Prevention of Nausea and Vomiting Following Upper Abdominal Surgeries under General Anaesthesia: A Randomised Control Trial [PDF]
Introduction: Postoperative Nausea and Vomiting (PONV) is a common entity following surgical procedure. It may result into serious complication like aspiration of gastric contents, prolonged recovery period.
Deepak Premnarayan Gupta, Vijay Chandak
doaj +1 more source
Is PONV still a problem in pediatric surgery: a prospective study of what children tell us
BackgroundPostoperative nausea and vomiting (PONV) is an unpleasant complication after surgery that commonly co-occurs with pain. Considering the high prevalence among pediatric patients, it is important to explore the main risk factors leading to PONV ...
Brigitte Messerer +8 more
doaj +1 more source
Metoclopramide Neurological Side Effects Screening; A Pharmacovigilence Study in Romanian Community Pharmacies [PDF]
Background. Metoclopramide is a pharmacological agent frequently used in therapy against nausea and vomiting that can occur in indigestion, motion sickness, gastric ulcer, pyloric spasm and after surgery as a side effect of some anesthetics.
Junghină, Adrian +4 more
core +8 more sources
Association of ABCB1, 5-HT3B receptor and CYP2D6 genetic polymorphisms with ondansetron and metoclopramide antiemetic response in Indonesian cancer patients treated with highly emetogenic chemotherapy. [PDF]
Our study shows that in Indonesian cancer patients treated with highly cytostatic emetogenic, carriership of the CTG haplotype of the ABCB1 gene is related to an increased risk of delayed chemotherapy-induced nausea and ...
Baak-Pablo, Renee F +8 more
core +2 more sources
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Helping patients discuss CINV management : development of a patient charter [PDF]
In April 2012, an Expert Group of specialist cancer nurses working in a variety of settings (e.g. chemotherapy delivery, chemotherapy service design, research, nurse leadership and patient information/advocacy) participated in telephone/web-based ...
Dielenseger, Pascale +9 more
core +1 more source
Quercetin (QUA), a flavonoid compound, is ubiquitously found in plants and has demonstrated a diverse range of biological activities. The primary objective of the current study is to assess the potential antiemetic properties of QUA using an in vivo and ...
Raihan Chowdhury +7 more
doaj +1 more source

