Results 21 to 30 of about 23,984 (264)

Study of antiemetic pattern on cancer patients with cancer by cytostatic therapy hospitals in Yogyakarta [PDF]

, 2006
The aim of the research was to know the description of antiemetic usage on the patients with cancer based on the medical records that were available in the hospital. Hereby, the use of antiemetic would be compared to literature for seeing the pattern.The
Perwitasari, Dyah Aryani; Faculty of Pharmacy Universitas Ahmad Dahlan Yogyakarta
core   +1 more source

Antiemetic research: future directions

, 2010
PURPOSE AND METHODS: As a part of reviewing the Multinational Association of Supportive Care in Cancer (MASCC) antiemetic guidelines in Perugia in 2009, an expert group identified directions for future antiemetic research.
Olver, Ian, Matti Aapro, Herrstedt, Jørn, Ian Olver, Morrow, Garry, Grunberg, Steven, Jørn Herrstedt, Alexander Molassiotis, Molassiotis, Alexander, Steven Grunberg, Aapro, Matti, Garry Morrow   +11 more
core   +1 more source

Cost-effectiveness and efficacy of combined dexamethasone–metoclopramide versus ondansetron in the prevention of postoperative nausea and vomiting in women undergoing myomectomy under spinal anesthesia

Bali Journal of Anesthesiology, 2019
Background: Postoperative nausea and vomiting (PONV) is a common complication following surgery under spinal anesthesia. The aim of this study was to compare the efficacy and cost-effectiveness of metoclopramide–dexamethasone combination with ondansetron
T A Ogbo, I T Ekwere, Kingsley Ufuoma Tobi, N P Edomwonyi   +3 more
doaj   +1 more source

Design and Characterization of Phosphatidylcholine-Based Solid Dispersions of Aprepitant for Enhanced Solubility and Dissolution

Pharmaceutics, 2020
This study aimed to improve the solubility and dissolution of aprepitant, a drug with poor aqueous solubility, using a phosphatidylcholine (PC)-based solid dispersion system.
Sooho Yeo, Jieun An, Changhee Park, Dohyun Kim, Jaehwi Lee   +4 more
doaj   +1 more source

A scoping review of thresholds for responder and time‐to‐event analysis of patient‐reported outcomes in breast cancer trials

British Journal of Clinical Pharmacology, EarlyView.
Patient‐reported outcomes (PROs) are essential for assessing clinical benefit and tolerability from the patient's perspective. In oncology trials, PRO data analysis often involves responder and time‐to‐event analyses, which depend on predefined thresholds to determine clinically meaningful change.
Anna Margarete Maria Thurner, Daniela Krepper, Micha Johannes Pilz, Lisa Marie Storz, Maike Thumfart, Johannes Maria Giesinger   +5 more
wiley   +1 more source

Prevention of Postoperative Nausea and Vomiting in Early Recovery: A Comparative Study of Ondansetron and Metoclopramide in Adults Undergoing Elective Lower Abdominal Surgery

AUIQ Complementary Biological System
Postoperative nausea and vomiting (PONV) remain common complications following surgery, despite the availability of various prophylactic antiemetic agents. This study aimed to compare the effectiveness of ondansetron and metoclopramide in preventing PONV
Majid Fakhir Al-Hamaidah , Ali Ihsan Abdul Mahdi , Maytham Alaa Shahid , Sajjad Salih Rasan , Lina M. Shaker , Shahab Abdulla, Ralela Makline   +6 more
doaj   +1 more source

Olanzapine for the Prevention and Treatment of Chemotherapy-Induced Nausea and Vomiting: A Review to Identify the Best Way to Administer the Drug

Current Oncology, 2022
Common treatment methods for malignant tumors include surgery, chemotherapy, radiotherapy, immunotherapy, targeted therapy, etc., among which chemotherapy plays an important role.
Xiao-Ling Zhang, Jie-Er Ying
doaj   +1 more source

International antiemetic guidelines on chemotherapy induced nausea and vomiting (CINV) : content and implementation in daily routine practice

, 2014
Over the past decades major improvements in the management of chemotherapy induced nausea and vomiting (CINV) were obtained. With the correct use of antiemetic drugs, CINV can be prevented in almost 70%, and even up to, 80% of patients.
Gralla, R, Molassiotis, A, Molasiotis, A., Jahn, F., Jahn, F, Gralla, R., Jordan, K, Jordan, K.   +7 more
core   +1 more source

Current practice and guideline adherence in renal dose adjustment for patients with chronic kidney disease: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims To quantify prescribing adherence to renal dosing recommendations in adults with chronic kidney disease (CKD; Stage 3 and above) and to evaluate the clinical consequences of non‐adherence. Methods This systematic review and meta‐analysis was conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD42025620883).
Hager ElGeed, Ahmed Tehemar, Mohamed Gasimelseed, Ahmed Gharaibeh, Muhammad Abdul Hadi, Kazeem Yusuff, Amani Zidan, Ahmed Awaisu   +7 more
wiley   +1 more source

Outcomes of Patients with Aortic Diseases Treated by Antiemetic Drug, Who Were Transported by a Physician-staffed Helicopter in Japan

Journal of Emergencies, Trauma and Shock
Introduction: Aortic diseases have been observed to manifest the symptoms such as nausea and vomiting. We conducted a retrospective investigation to ascertain the clinical significance of antiemetic drug use for patients with aortic diseases transported ...
Youichi Yanagawa, Hiroki Nagasawa, Chihiro Maekawa, Noriko Tanaka, Michika Hamada, Soichiro Ota, Hiromichi Ohsaka, Kazuhiko Omori   +7 more
doaj   +1 more source