Results 11 to 20 of about 18,399 (161)

Evidence for Bell-Shaped Dose-Response Emetic Effects of Temsirolimus and Analogs: The Broad-Spectrum Antiemetic Efficacy of a Large Dose of Temsirolimus Against Diverse Emetogens in the Least Shrew (Cryptotis parva)

Frontiers in Pharmacology, 2022
Temsirolimus is a prodrug form of sirolimus (rapamycin). With its analogs (everolimus, ridaforolimus, and rapamycin), it forms a group of anticancer agents that block the activity of one of the two mammalian targets of rapamycin (mTOR) complexes, mTORC1.
Louiza Belkacemi, Yina Sun, Nissar A. Darmani   +2 more
doaj   +1 more source

Comparative Study of Lidocaine and Palonosetron Pretreatment in Reduction of Propofol Induced Injection Pain [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Propofol is very popular as an induction agent in modern day anaesthesia because of its favourable pharmacodynamics and fewer side effects. Any pain pre or post-anaesthesia leads to patient dissatisfaction.
Suruchi Ambasta, Swagat Mahapatra
doaj   +1 more source

Cyclic vomiting syndrome (CVS) responsive to single-dose olanzapine: a case report [PDF]

Exploration of Neuroscience
Cyclic vomiting syndrome (CVS) is a rare disorder in which stereotypical periods of intermittent nausea and vomiting last between hours and over a week.
Sara Sipilä, Kirsi Kallio, Virpi Sidoroff, Marika Jantunen, Jussi O.T. Sipilä   +4 more
doaj   +1 more source

Monitoring the adherence to an adapted evidence-based clinical practice guideline on antiemetics in 669 patients with cancer receiving 1451 chemotherapy doses at a University oncology center in Saudi Arabia

Journal of Nature and Science of Medicine, 2021
Objectives: Chemotherapy-induced nausea and vomiting (CINV) is a common medication safety issue among cancer patients worldwide. However, there remains a research gap on adherence to the clinical practice guidelines (CPGs) for antiemetic medications to ...
Haya Fahad Al-Salloum, Yasser Sami Amer, Khalid Abdulrahman Alsaleh   +2 more
doaj   +1 more source

An Update in Our Understanding of the Relationships Between Gene Polymorphisms and Chemotherapy-Induced Nausea and Vomiting

International Journal of General Medicine, 2021
Yilan Jin,* Xiaorong Li,* Caihong Jiang,* Jun Zhao, Guang Liu, Hui Li, Gaowa Jin, Quanfu Li Department of Medical Oncology, Ordos Central Hospital, Ordos, 017000, People’s Republic of China*These authors contributed equally to this ...
Jin Y, Li X, Jiang C, Zhao J, Liu G, Li H, Jin G, Li Q   +7 more
doaj  

Effect of 5% Dextrose Infusion on Postoperative Nausea and Vomiting in Patients undergoing Laparoscopic Cholecystectomy: A Randomised Controlled Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Postoperative Nausea and Vomiting (PONV) is defined as nausea, vomiting, or retching occurring in the postanaesthesia care unit within the first 24 hours of postoperative period. It is most common following laparoscopic cholecystectomy,
BR Lakshmi, Roopashree Nanjundappa, Vithal Kulkarni   +2 more
doaj   +1 more source

Design and Characterization of Phosphatidylcholine-Based Solid Dispersions of Aprepitant for Enhanced Solubility and Dissolution

Pharmaceutics, 2020
This study aimed to improve the solubility and dissolution of aprepitant, a drug with poor aqueous solubility, using a phosphatidylcholine (PC)-based solid dispersion system.
Sooho Yeo, Jieun An, Changhee Park, Dohyun Kim, Jaehwi Lee   +4 more
doaj   +1 more source

Olanzapine for the Prevention and Treatment of Chemotherapy-Induced Nausea and Vomiting: A Review to Identify the Best Way to Administer the Drug

Current Oncology, 2022
Common treatment methods for malignant tumors include surgery, chemotherapy, radiotherapy, immunotherapy, targeted therapy, etc., among which chemotherapy plays an important role.
Xiao-Ling Zhang, Jie-Er Ying
doaj   +1 more source

Cost-effectiveness and efficacy of combined dexamethasone–metoclopramide versus ondansetron in the prevention of postoperative nausea and vomiting in women undergoing myomectomy under spinal anesthesia

Bali Journal of Anesthesiology, 2019
Background: Postoperative nausea and vomiting (PONV) is a common complication following surgery under spinal anesthesia. The aim of this study was to compare the efficacy and cost-effectiveness of metoclopramide–dexamethasone combination with ondansetron
T A Ogbo, I T Ekwere, Kingsley Ufuoma Tobi, N P Edomwonyi   +3 more
doaj   +1 more source

Therapeutic study of the nausea and vomiting caused by chemotherapy medications by olanzapine to triple antiemetic therapy in Iraqi cancer patients

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2023
Background:Chemotherapy-caused nausea and vomiting is a health problem in cancer patients. Olanzapine is used with serotonin receptor antagonists plus dexamethasone post Neurokinin 1 receptor antagonists as the antiemetic.
Ghufran salah ahmed, khadim ali khadim2, nabeel mudheher talib   +2 more
doaj   +1 more source