Results 21 to 30 of about 28,252 (96)

Nausea: Current knowledge of mechanisms, measurement and clinical impact [PDF]

open access: yes, 2015
Nausea is a subjective sensation, which often acts as a signal that emesis is imminent. It is a widespread problem that occurs as a clinical sign of disease or as an adverse effect of a drug therapy or surgical procedure.
Aapro   +104 more
core   +1 more source

Bimodal release ondansetron for acute gastroenteritis among adolescents and adults: A randomized clinical trial [PDF]

open access: yes, 2019
Importance: Vomiting resulting from acute gastroenteritis is commonly treated with intravenous antiemetics in acute care settings. If oral treatment were beneficial, patients might not need intravenous administered hydration or medication. Furthermore, a
Avarello, Jahn   +11 more
core   +2 more sources

The impact of 5-hydroxytryptamine-receptor antagonists on chemotherapy treatment adherence, treatment delay, and nausea and vomiting. [PDF]

open access: yes, 2015
PurposeTo determine the incidence of chemotherapy-induced nausea/vomiting (CINV) and chemotherapy treatment delay and adherence among patients receiving palonosetron versus other 5-hydroxytryptamine receptor antagonist (5-HT3 RA) antiemetics.Materials ...
Grabner, Michael   +3 more
core   +2 more sources

Cisplatin-induced emesis: systematic review and meta-analysis of the ferret model and the effects of 5-HT3 receptor antagonists [PDF]

open access: yes, 2010
PURPOSE: The ferret cisplatin emesis model has been used for ~30 years and enabled identification of clinically used anti-emetics. We provide an objective assessment of this model including efficacy of 5-HT(3) receptor antagonists to assess its ...
A Fink-Jensen   +153 more
core   +2 more sources

Genetic and Modifiable Risk Factors Contributing to Cisplatin-Induced Toxicities [PDF]

open access: yes, 2019
Effective administration of traditional cytotoxic chemotherapy is often limited by off-target toxicities. This clinical dilemma is epitomized by cisplatin, a platinating agent that has potent antineoplastic activity due to its affinity for DNA and other ...
Dinh, Paul C. Jr.   +4 more
core   +1 more source

2023 Updated MASCC/ESMO Consensus Recommendations: prevention of radiotherapy-and chemoradiotherapy-induced nausea and vomiting [PDF]

open access: yes, 2023
Purpose Radiotherapy and chemoradiotherapy-induced nausea and vomiting (RINV and C-RINV) are common and distressing, and there is a need for guidance for clinicians to provide up to date optimal antiemetic prophylaxis and treatment.
Dennis, K.   +5 more
core   +1 more source

Cannabinoid Hyperemesis Syndrome [PDF]

open access: yes, 2015
Legalization of marijuana use will increase the number of people who will become long-term users. A prior medical record review study in Australia, in 2004, identified 19 chronic marijuana users who entered the emergency department with recurrent ...
Heise, Lynn
core   +2 more sources

Effects of Modification of Pain Protocol on Incidence of Post Operative Nausea and Vomiting. [PDF]

open access: yes, 2016
BackgroundA Perioperative Surgical Home (PSH) care model applies a standardized multidisciplinary approach to patient care using evidence-based medicine to modify and improve protocols.
Ahn, Kyle   +7 more
core   +2 more sources

Metoclopramide Neurological Side Effects Screening; A Pharmacovigilence Study in Romanian Community Pharmacies [PDF]

open access: yes, 2015
Background. Metoclopramide is a pharmacological agent frequently used in therapy against nausea and vomiting that can occur in indigestion, motion sickness, gastric ulcer, pyloric spasm and after surgery as a side effect of some anesthetics.
Junghină, Adrian   +4 more
core   +7 more sources

Economic evaluation of ondansetron: Preliminary analysis using clinical trial data prior to price setting [PDF]

open access: yes, 1992
This article has been made available through the Brunel Open Access Publishing Fund and is available from the specified link - Copyright © 1992 Macmillan Press Ltd.This study combines secondary analysis of efficacy and side-effect data from a randomised ...
Buxton, MJ, O'Brien, BJ
core   +1 more source

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