Results 41 to 50 of about 30,843 (290)

Bimodal release ondansetron for acute gastroenteritis among adolescents and adults: A randomized clinical trial [PDF]

, 2019
Importance: Vomiting resulting from acute gastroenteritis is commonly treated with intravenous antiemetics in acute care settings. If oral treatment were beneficial, patients might not need intravenous administered hydration or medication. Furthermore, a
Avarello, Jahn, Fathi, Reza, Hahn, Barry, House, Stacey L, Kalfus, Ira N, Lovato, Luis M, Meltzer, Andrew C, Miller, Joseph B, Plasse, Terry F, Raday, Gilead, Silverman, Robert A, Yan, Eric C   +11 more
core   +2 more sources

Progression of lipase activity and pancreatic lipase immunoreactivity in dogs hospitalized for acute pancreatitis and correlation with clinical features

Journal of Veterinary Internal Medicine, Volume 37, Issue 1, Page 70-79, January/February 2023., 2023
Abstract Background Lipase activity and pancreatic lipase immunoreactivity (PLI) have not been compared in dogs hospitalized for acute pancreatitis (AP). Objectives To describe the progression of lipase activity and PLI, and correlations with clinicopathologic features in dogs with AP. Animals Thirty‐nine dogs with AP based on clinical signs and lipase
Claudia Cueni, Natalie Hofer‐Inteeworn, Claudia Kümmerle‐Fraune, Claudia Müller, Peter Hendrik Kook   +4 more
wiley   +1 more source

Adherence to guidelines on prophylaxis of chemotherapy-induced nausea and vomiting in the National Cancer Institute, Sudan

South African Journal of Oncology, 2017
Objective: To evaluate the adherence to American Society of Clinical Oncology (ASCO) guidelines for antiemetic prophylaxis of chemotherapy-induced nausea and vomiting and assess the outcomes of the prescribed antiemetic drugs. Methods: This prospective,
Moawia M.A. Elhassan, Arwa A.S.A. Ali, Mohamed O.M. Elmustafa   +2 more
doaj   +1 more source

Clinical and clinicopathological features and outcomes of cats with suspected dietary induced pancytopenia

Journal of Veterinary Internal Medicine, Volume 37, Issue 1, Page 126-132, January/February 2023., 2023
Abstract Background After a strong epidemiological link to diet was established in an outbreak of pancytopenia in cats in spring 2021 in the United Kingdom, 3 dry diets were recalled. Concentrations of the hemato‐ and myelotoxic mycotoxins T‐2, HT‐2 and diacetoxyscirpenol (DAS) greater than the European Commission guidance for dry cat foods were ...
Barbara Glanemann, Karen Humm, Mariana Abreu, Sophie Aspinall, David Buckeridge, Hope Carveth, Hannah Darcy, Jessica Florey, Polly Frowde, Isuru Gajanayake, Kate Green, Emma Holmes, Alenka Hrovat, Anne‐Katherine Jasensky, Bryn A Jones, Vasiliki Lantzaki, Eve JY Lo, Kirsty MacDonald, Kevin O'Brien, Alejandro Suárez‐Bonnet, Nele Van den Steen, Balazs Szladovits, Annelies Willems, Helen Wilson   +23 more
wiley   +1 more source

The impact of 5-hydroxytryptamine-receptor antagonists on chemotherapy treatment adherence, treatment delay, and nausea and vomiting. [PDF]

, 2015
PurposeTo determine the incidence of chemotherapy-induced nausea/vomiting (CINV) and chemotherapy treatment delay and adherence among patients receiving palonosetron versus other 5-hydroxytryptamine receptor antagonist (5-HT3 RA) antiemetics.Materials ...
Grabner, Michael, Palli, Swetha Rao, Quimbo, Ralph A, Rugo, Hope S   +3 more
core   +2 more sources

New antiemetic drugs

Annals of Oncology, 2006
Important progress in the prophylaxis of chemotherapy-induced acute and delayed emesis has been achieved but some fundamental needs still remain that requires new, efficacious antiemetic drugs.A critical review of the results of published studies of aprepitant, a new NK1 receptor antagonist, and of palonosetron, a 5-HT3 receptor antagonist with a ...
Roila F, Fatigoni S
openaire   +3 more sources

Ondansetron induced torsades de pointes

Clinical Case Reports, 2019
A single dose of oral Ondansetron can precipitate torsades de pointes and other arrhythmias in patients with risk factors that may prolong QTc interval.
Eshan Patel, Danielle Rosemond, Ashwad Afzal   +2 more
doaj   +1 more source

Cisplatin-induced emesis: systematic review and meta-analysis of the ferret model and the effects of 5-HT3 receptor antagonists [PDF]

, 2010
PURPOSE: The ferret cisplatin emesis model has been used for ~30 years and enabled identification of clinically used anti-emetics. We provide an objective assessment of this model including efficacy of 5-HT(3) receptor antagonists to assess its ...
A Fink-Jensen, A Lehmann, A Ozaki, AG King, AH Lau, AL Harris, AM Holmes, AP Florczyk, AP Florczyk, B Costall, B Costall, B Costall, B Costall, B Costall, B Costall, B Lasheras, C Bountra, C. C. Apfel, CJ Gardner, CJ Gardner, CJ Gardner, CL Gooch, D Moher, D Spina, D Tattersall, D Tattersall, DG Altman, DJ Reynolds, DR Gandara, E Blum, E Chevalier, F Roila, FD Tattersall, FD Tattersall, FD Tattersall, GA Higgins, GJ Hollingworth, H Nakayama, H Yamakuni, H Yamakuni, HE Marr, HE Marr, HE Marr, HL Borison, I Angel, I Monkovic, IT Jantunen, J Bermudez, J Hawthorn, J Horn, J Horn, J. A. Rudd, JA Gylys, JA Rudd, JA Rudd, JA Rudd, JA Rudd, JA Rudd, JA Rudd, JA Rudd, JA Rudd, JA Rudd, JA Rudd, JA Rudd, JA Rudd, JA Rudd, JE Schurig, JH Kim, JJ Hale, JJ Hale, JM Barnes, JN Matthews, JW Watson, K Haga, K Haga, L Singh, LE McCarthy, LR Fitzpatrick, LX Cubeddu, M Martin, M Marty, M Minami, M Minami, M Minami, M Ohta, M Tsuchiya, MD Sickle Van, MG Kris, MG Kris, MR Macleod, MR Macleod, MR Macleod, MT Price, N Fukunaka, N Percie du Sert, N Yoshida, N Yoshida, N Yoshida, N Yoshida, N. Percie du Sert, NM Barnes, NM Barnes, NM Rupniak, P Bhandari, P Delagrange, P Pound, P Preziosi, P Ruff, P. L. R. Andrews, PJ Hesketh, PJ Hesketh, PLR Andrews, PLR Andrews, PR Blower, R DerSimonian, R Hargreaves, R Stables, RA Matthews, RC Miller, RD Clark, RD Youssefyeh, RD Youssefyeh, RM Eglen, RM Eglen, RM Eglen, RM Navari, S Bingham, S Gonsalves, S Taniguchi, T Endo, T Endo, T Endo, T Endo, T Endo, T Ito, T Kamato, T Kamato, T Matsui, T Yoshikawa, T Yoshikawa, T Yoshikawa, TM Dando, TS Sam, TS Sam, TS Sam, V Bebarta, WD Miner, WD Miner, WD Miner, Y Kubota, Y Shiroshita, Y Shiroshita, Y Watanabe, YL Liu   +153 more
core   +2 more sources

Efficacy of NEPA, a fixed antiemetic combination of netupitant and palonosetron, vs a 3‐day aprepitant regimen for prevention of chemotherapy‐induced nausea and vomiting (CINV) in Chinese patients receiving highly emetogenic chemotherapy (HEC) in a randomized Phase 3 study

Cancer Medicine, 2020
NEPA is the only fixed combination antiemetic, comprised of an NK1RA (netupitant) and a 5‐HT3RA (palonosetron). In the first head‐to‐head trial to compare NK1RA‐containing regimens, a single oral dose of NEPA was non‐inferior to a 3‐day aprepitant ...
Jianhua Chang, Gongyan Chen, Dong Wang, Guihua Wang, Shun Lu, Jifeng Feng, Wei Li, Ping Li, Corinna Lanzarotti, Salvatore Chessari, Li Zhang   +10 more
doaj   +1 more source

Design and Characterization of Phosphatidylcholine-Based Solid Dispersions of Aprepitant for Enhanced Solubility and Dissolution

Pharmaceutics, 2020
This study aimed to improve the solubility and dissolution of aprepitant, a drug with poor aqueous solubility, using a phosphatidylcholine (PC)-based solid dispersion system.
Sooho Yeo, Jieun An, Changhee Park, Dohyun Kim, Jaehwi Lee   +4 more
doaj   +1 more source