Results 141 to 150 of about 22,164 (248)

Evaluation of Potentially Inappropriate Medications Prescribed to Older Adults Upon Emergency Department Discharge

Academic Emergency Medicine, Volume 33, Issue 3, March 2026.
ABSTRACT Background Older adults are susceptible to adverse drug effects due to age‐related changes, a higher prevalence of comorbidities, and complexities in medication management. Nearly half of geriatric patients are prescribed at least one new medication at ED discharge.
Jessica Schowe, Andrew M. North, Kyle Schuchter, Katherine M. Hunold, Elizabeth Rozycki   +4 more
wiley   +1 more source

QT Myopia and Cardiac Safety: Expanding the Aperture of Arrhythmia Assessment in Early Phase Drug Development

Clinical and Translational Science, Volume 19, Issue 3, March 2026.
ABSTRACT Regulatory agencies such as the Food and Drug Administration (FDA), European Medicines Agency (EMA), Health Canada, and the Japanese Pharmaceutical and Medical Device Agency (PMDA) provide scientific and public health guidance with cardiac safety being paramount in drug development of new investigational products (IP).
Robert M. Lester, Katherine Clark, Sabina Paglialunga   +2 more
wiley   +1 more source

Incidence of and risk factors for postoperative nausea and vomiting at a Japanese Cancer Center: first large-scale study in Japan [PDF]

, 2012
MORINO Ryozo, NAGATA Osamu, OZAKI Makoto, YOKOTA Miyuki   +3 more
core   +2 more sources

Impact of CYP2D6 Metabolizer Status on Ondansetron Efficacy in Early Pregnancy Induced Nausea and Vomiting: A Case Control Study

Clinical and Translational Science, Volume 19, Issue 3, March 2026.
ABSTRACT Real‐world data investigating CYP2D6 on the efficacy of ondansetron for nausea and vomiting in pregnancy (NVP) is lacking. Evidence shows CYP2D6 ultrarapid metabolizers are at risk of ondansetron nonresponse due to increased metabolism. We conducted a retrospective cohort study of early pregnant patients on ondansetron for NVP.
Michelle Liu, Megan M. Shuey, Sabrina E. Holley, Darlene F. Fountain, James Jaworski, Carol Griffin, Jeewoo Kim, Melissa Stec, Sudeep D. Sunthankar, Henry H. Ong, Srushti Gangireddy, Wei‐Qi Wei, Andrea Gaedigk, Digna R. Velez Edwards, Vivian K. Kawai   +14 more
wiley   +1 more source

Metabolism and Excretion of Intravenous, Radio-Labeled Amisulpride in Healthy, Adult Volunteers

Clinical Pharmacology: Advances and Applications, 2019
Gabriel M Fox,1 Ad F Roffel,2 Jan Hartstra,2 Linda A Bussian,3 Sjoerd P van Marle2 1Department of Clinical Development, Acacia Pharma Ltd, Cambridge, UK; 2PRA Health Sciences, Groningen, the Netherlands; 3Comedica Ltd, Cambridge, UKCorrespondence ...
Fox GM, Roffel AF, Hartstra J, Bussian LA, van Marle SP   +4 more
doaj  

Study participant impression of use and satisfaction with STS101 (dihydroergotamine nasal powder): Results from the open‐label ASCEND acute migraine study

Headache: The Journal of Head and Face Pain, Volume 66, Issue 3, Page 688-696, March 2026.
Abstract Objective/Background This study was undertaken to assess participants' impression of use and satisfaction with STS101 in a long‐term, open‐label safety study. The ASCEND study assessed the safety and tolerability of STS101, an investigational drug–device combination of 5.2 mg dihydroergotamine in a single‐use nasal delivery device for the ...
Jessica Ailani, Larry Charleston IV, Shannon Strom, Detlef Albrecht, Robert Cowan   +4 more
wiley   +1 more source

Patient factors and costs associated with prophylactic neurokinin-1 receptor antagonist use among women with invasive breast cancer. [PDF]

J Manag Care Spec Pharm
Kamat S, Brown BR, Cohen SA, Vyas A.
europepmc   +1 more source

Challenges of Parents While Providing Complex Medical Care at Home to Children With Cancer: A Cross‐Sectional Convergent Mixed Methods Study

Journal of Clinical Nursing, Volume 35, Issue 3, Page 1234-1243, March 2026.
ABSTRACT Aim To explore challenges parents of children with cancer encounter while providing complex medical care at home. Methods Design: Cross‐sectional convergent mixed‐methods study. Instruments: Questionnaire and open interviews that mirrored and complemented each other.
Rachel Klausner Shyman, Sveta Roberman, Gal Goldstein, Sabaa Masarwe, Amy Solnica, Rachel Yaffa Zisk‐Rony   +5 more
wiley   +1 more source

Comparison of aprepitant, dexamethasone, and ondansetron with dexamethasone and ondansetron for prevention of postoperative nausea and vomiting in high-risk patients undergoing laparoscopic surgeries: a randomized controlled trial in India. [PDF]

J Minim Invasive Surg
Bala S, Meshram TM, Bhatia P, Rathod D, Kaur M, Kumari K.   +5 more
europepmc   +1 more source

Clinical guidelines highlight for the hospitalist: Management of cyclic vomiting syndrome in children

Journal of Hospital Medicine, Volume 21, Issue 3, Page 291-293, March 2026.
Yamileth N. Hernandez, Hannah M. Gardner
wiley   +1 more source