Results 1 to 10 of about 8,320 (205)

Antifibrinolytic agents in traumatic haemorrhage [PDF]

Indian Journal of Pharmacology, 2005
Among trauma patients who survive to reach hospital, exsanguination is a common cause of death. Could anti fibrinolytics reduce the death rate?
Coats, Timothy J., Hunt, Beverly, Roberts, Ian, Shakur, Haleema   +3 more
doaj   +11 more sources

Antifibrinolytics in liver surgery

Indian Journal of Anaesthesia, 2010
Hyperfibrinolysis, a known complication of liver surgery and orthotopic liver transplantation (OLT), plays a significant role in blood loss. This fact justifies the use of antifibrinolytic drugs during these procedures. Two groups of drug namely lysine analogues [epsilon aminocaproic acid (EACA) and tranexamic acid (TA)] and serine-protease-inhibitors (
Jyotsna Goswami, Jalpa D. Makwana, Saloni Paranjape   +2 more
openaire   +5 more sources

FIBRINOLYTIC AND ANTIFIBRINOLYTIC ACTIVITY IN PREGNANCY [PDF]

Journal of Clinical Pathology, 1960
Fibrinolytic activity and serum antifibrinolysin were estimated in normal pregnant women, during and after labour.The decreased fibrinolytic activity found during labour returned to non-pregnant levels within 24 hours of delivery. During the same period, the serum antifibrinolysin was rapidly diminished.It is suggested that the post-partum increase in ...
M. Hathorn, S. S. Naidoo, T. Gillman
openaire   +4 more sources

Antifibrinolytic therapy for aneurysmal subarachnoid haemorrhage

Cochrane Database of Systematic Reviews, 2022
Rebleeding is an important cause of death and disability in people with aneurysmal subarachnoid haemorrhage. Rebleeding is probably related to the dissolution of the blood clot at the site of the aneurysm rupture by natural fibrinolytic activity. This review is an update of previously published Cochrane Reviews.To assess the effects of antifibrinolytic
Germans, Menno R, Dronkers, Wouter J, Baharoglu, Merih I, Post, René, Verbaan, Dagmar, Rinkel, Gabriel Je, Roos, Yvo Bwem   +6 more
openaire   +6 more sources

Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal

Periodontology 2000, EarlyView., 2023
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra, Hélène Rangé, Giuseppina Caligiuri, Philippe Bouchard   +3 more
wiley   +1 more source

Using antifibrinolytics to tackle neuroinflammation

Neural Regeneration Research, 2020
Plasmin is generally known as a promotor of inflammation. Recent advancement suggests that it has a complex role as immunity modulator. Pharmacological inhibition of plasmin production and activity has been proven to improve neurological outcomes in traumatic brain injury and subarachnoid hemorrhage, most probably by preventing re-bleeding.
Atsev, Stanimir, Tomov, Nikola Stefanov
openaire   +5 more sources

Antifibrinolytic drugs and perioperative hemostasis [PDF]

American Journal of Hematology, 1997
Although excessive bleeding is widely recognized as a common complication of cardiac surgery, the recent success of antifibrinolytic drugs as prophylactic hemostatic agents has received little attention outside the surgical literature. The etiology of the coagulopathy following cardiac surgery is clearly multifactorial; however, the success of ...
Charles S. Greenberg, Thomas F. Slaughter   +1 more
openaire   +3 more sources

Yerba Mate (Ilex paraguariensis St. Hill.) Tea May Have Cardiometabolic Beneficial Effects in Healthy and At‐Risk Subjects: A Randomized, Controlled, Blind, Crossover Trial in Nonhabitual Consumers

Molecular Nutrition &Food Research, EarlyView.
Yerba mate intake shows cardiometabolic beneficial effects decreasing blood pressure, blood lipids, inflammatory biomarkers and body fat in healthy and hypercholesterolemic non‐habitual consumers. ABSTRACT Yerba mate has been reported to have antihypertensive, hypocholesterolemic, antidiabetic, or antiobesity properties.
Laura Bravo, Sara Martínez‐López, Jose Luis Sierra‐Cinos, Raquel Mateos, Beatriz Sarriá   +4 more
wiley   +1 more source

Reducing Surgery for Pediatric Posttonsillectomy Hemorrhage Using Tranexamic Acid: A Quality Improvement Initiative

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Evaluate the use of tranexamic acid (TXA) and observation as a management option for pediatric patients presenting with posttonsillectomy hemorrhage (PTH). Study Design Retrospective analysis of a prospectively implemented quality improvement initiative with a historical control comparison group. Setting Tertiary children's hospital.
Laura A. Petrauskas, Janavi Sethurathnam, Ansley J. Kunnath, Rahul K. Sharma, John Ceremsak, Ryan H. Belcher, James D. Phillips, Jay A. Werkhaven, Amy S. Whigham, Lyndy J. Wilcox, Christopher T. Wootten, Frank W. Virgin, Jason S. Park   +12 more
wiley   +1 more source

Antifibrinolytics in cardiac surgery

Annals of Cardiac Anaesthesia, 2013
Cardiac surgery exerts a significant strain on the blood bank services and is a model example in which a multi-modal blood-conservation strategy is recommended. Significant bleeding during cardiac surgery, enough to cause re-exploration and/or blood transfusion, increases morbidity and mortality.
openaire   +4 more sources