Is Antifibrinolytic Therapy Effective for Preventing Hemorrhage in Patients with Hemophilia Undergoing Dental Extractions? A Systematic Review and Meta-Analysis [PDF]
Clinical and Applied Thrombosis/Hemostasis, 2022 Objectives This systematic review aims to analyze the systemic administration of antifibrinolytics (tranexamic acid and aminocaproic acid) to prevent postoperative bleeding in patients with hemophilia.
Kaleem Ullah MBBS +4 more
doaj +2 more sources
In Vivo Assessment of Thermosensitive Liposomes for the Treatment of Port Wine Stains by Antifibrinolytic Site-Specific Pharmaco-Laser Therapy [PDF]
Pharmaceutics, 2020 Antifibrinolytic site-specific pharmaco-laser therapy (SSPLT) is an experimental treatment modality for refractory port wine stains (PWS). Conceptually, antifibrinolytic drugs encapsulated in thermosensitive liposomes are delivered to thrombi that form ...
Mingjuan Li +10 more
doaj +2 more sources
Benefits of Antifibrinolytics in Minimally Invasive Surgical Repair of Single-suture Craniosynostosis [PDF]
Plastic and Reconstructive Surgery, Global OpenBackground:. The utility of antifibrinolytics in minimally invasive craniosynostosis repair lacks established consensus. This study aimed to assess the impact of antifibrinolytic administration on intraoperative blood loss; length of hospital stay ...
Gabrielle C. Rodriguez, MD +7 more
doaj +2 more sources
Efficacy and safety of using antifibrinolytic agents in spine surgery: a meta-analysis. [PDF]
PLoS ONE, 2013 PURPOSE: Spine surgery, particularly reconstructive surgery, can be associated with significant blood loss, and blood transfusion. Antifibrinolytic agents are used routinely to reduce bleeding in cardiac, orthopaedic, and hepatic surgery.
Chaoqun Yuan, Hailong Zhang, Shisheng He
doaj +3 more sources
Antifibrinolytic agents in traumatic haemorrhage. [PDF]
PLoS Medicine, 2005 Among trauma patients who survive to reach hospital, exsanguination is a common cause of death. Could anti fibrinolytics reduce the death rate?
Tim Coats +3 more
doaj +9 more sources
Multidisciplinary Collaborative Efforts in Craniosynostosis Surgery—A Rural Appalachian Institutional Experience in Patient Care and Outcomes [PDF]
International Journal of PediatricsCraniosynostosis surgery, addressing the premature fusion of cranial sutures, presents a unique challenge requiring standardized care, especially in rural settings, to optimize patient outcomes.
Brittany McLay +10 more
doaj +2 more sources
Antifibrinolytics in liver surgery
Indian Journal of Anaesthesia, 2010 Hyperfibrinolysis, a known complication of liver surgery and orthotopic liver transplantation (OLT), plays a significant role in blood loss. This fact justifies the use of antifibrinolytic drugs during these procedures.
Jalpa Makwana +2 more
doaj +3 more sources
Antifibrinolytic Role of a Bee Venom Serine Protease Inhibitor That Acts as a Plasmin Inhibitor [PDF]
PLoS ONE, 2012 Bee venom is a rich source of pharmacologically active substances. In this study, we identified a bumblebee (Bombus ignitus) venom Kunitz-type serine protease inhibitor (Bi-KTI) that acts as a plasmin inhibitor.
Hu Wan
exaly +2 more sources
Scrub Typhus Combined With Septic Shock Disseminated Intravascular Coagulation and Significant Hyperfibrinolysis: A Case Report and Review of the Literature [PDF]
Case Reports in Infectious DiseasesConclusion: The fibrinolytic system in DIC caused by scrub typhus is excessively active, and antifibrinolytic therapy may benefit such patients. Further research on the distinct coagulation abnormalities in scrub typhus–associated DIC would be highly ...
Dewen Ma +7 more
doaj +2 more sources
Tranexamic Acid in Trauma Management: A Review of Evidence [PDF]
Journal of Acute Care Surgery, 2023 Hemorrhage is the leading cause of death in trauma patients and trauma induced coagulopathy (TIC) is a major contributor to bleeding mortality. TIC has a diverse pathophysiology triggered by injury and hypoperfusion, including platelet dysfunction ...
Namryeol Kim
doaj +1 more source