Scrub Typhus Combined With Septic Shock Disseminated Intravascular Coagulation and Significant Hyperfibrinolysis: A Case Report and Review of the Literature [PDF]
Case Reports in Infectious DiseasesConclusion: The fibrinolytic system in DIC caused by scrub typhus is excessively active, and antifibrinolytic therapy may benefit such patients. Further research on the distinct coagulation abnormalities in scrub typhus–associated DIC would be highly ...
Dewen Ma +7 more
doaj +2 more sources
Hyperfibrinolysis Detection During Liver Transplantation Using Viscoelastometry [PDF]
Clinical Transplantation, Volume 39, Issue 5, May 2025.ABSTRACT Background End‐stage liver disease induces a precarious hemostatic equilibrium, named rebalanced hemostasis. Liver transplantation additionally causes profound disturbances in the hemostatic balance. Hyperfibrinolysis poses a relevant impairment to the coagulation process during liver transplantation.
Sarah Thaler +6 more
wiley +2 more sources
Antifibrinolytic drugs for acute traumatic injury [PDF]
Cochrane Database of Systematic Reviews, 2011 Uncontrolled bleeding is an important cause of death in trauma victims. Antifibrinolytic treatment has been shown to reduce blood loss following surgery and may also be effective in reducing blood loss following trauma.To assess the effect of antifibrinolytic drugs in patients with acute traumatic injury.We ran the most recent search in January 2015 ...
Roberts, I, Shakur, H, Ker, K, Coats, T
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The effectiveness and safety of antifibrinolytics in patients with acute intracranial haemorrhage: statistical analysis plan for an individual patient data meta-analysis [version 1; referees: 2 approved] [PDF]
Wellcome Open Research, 2017 Introduction: The Antifibrinolytic Trialists Collaboration aims to increase knowledge about the effectiveness and safety of antifibrinolytic treatment by conducting individual patient data (IPD) meta-analyses of randomised trials.
Katharine Ker +7 more
doaj +2 more sources
Tranexamic Acid in Trauma Management: A Review of Evidence [PDF]
Journal of Acute Care Surgery, 2023 Hemorrhage is the leading cause of death in trauma patients and trauma induced coagulopathy (TIC) is a major contributor to bleeding mortality. TIC has a diverse pathophysiology triggered by injury and hypoperfusion, including platelet dysfunction ...
Namryeol Kim
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Antifibrinolytics in subarachnoid haemorrhage [PDF]
British Journal of Anaesthesia, 2014 G. Bird, S.R. Ford
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Effect of Intravenous Tranexamic Acid Administration on Blood Loss during and after Caesarean Delivery: A Randomised Controlled Study [PDF]
International Journal of Anatomy Radiology and Surgery, 2020 Introduction: India remains a major contributor to maternal deaths in the world. Haemorrhage after delivery (both vaginal & caesarean) is the leading cause. To reduce the haemorrhage, oxytocics are routinely used. In heavy bleeding, blood transfusion
Shyamali Dutta +2 more
doaj +1 more source
Effect of Local Tranexamic Acid on the Quality of Bone Healing in a Rat Spinal Fusion Model
Spine Surgery and Related Research, 2022 Introduction: The use of the antifibrinolytic agent tranexamic acid has positive effects on bleeding control, but our knowledge is still limited regarding how fibrinolysis suppression changes the process of bone formation and the quality of bone. Because
Ertugrul Sahin +5 more
doaj +1 more source
40. The Benefits of Antifibrinolytic Administration in Minimally Invasive Craniosynostosis Repair [PDF]
Plastic and Reconstructive Surgery, Global OpenGabrielle C. Rodriguez, MD +8 more
doaj +2 more sources
Comparative Study of Two Different Intravenous Doses of Tranexamic Acid with Placebo on Surgical Field Quality in Functional Endoscopic Sinus Surgery-A Randomised Clinical Trial [PDF]
Journal of Clinical and Diagnostic Research, 2019 Introduction: Intraoperative haemorrhage, which disrupts surgical patency, is a major obstacle for surgeons, especially in endoscopic sinus surgeries. Tranexamic acid is synthetic antifibrinolytic agent that binds competitively at lysine binding site on ...
Tamil Anbu Pannerselvam +2 more
doaj +1 more source