Results 11 to 20 of about 18,529 (289)
Compaction of fibrin clots reveals the antifibrinolytic effect of factor XIII [PDF]
Journal of Thrombosis and Haemostasis, 2016 Essentials Factor XIIIa inhibits fibrinolysis by forming fibrin-fibrin and fibrin-inhibitor cross-links. Conflicting studies about magnitude and mechanisms of inhibition have been reported.
Abdul, S. (Shiraazkhan) +4 more
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Antifibrinolytic drugs for acute traumatic injury [PDF]
São Paulo Medical Journal, 2011 Uncontrolled bleeding is an important cause of death in trauma victims. Antifibrinolytic treatment has been shown to reduce blood loss following surgery and may also be effective in reducing blood loss following trauma.To assess the effect of antifibrinolytic drugs in patients with acute traumatic injury.We ran the most recent search in January 2015 ...
Ian Roberts +3 more
doaj +12 more sources
Antifibrinolytic Agents in Traumatic Haemorrhage [PDF]
PLoS Medicine, 2005 Among trauma patients who survive to reach hospital, exsanguination is a common cause of death. Could anti fibrinolytics reduce the death rate?
Tim Coats +3 more
doaj +11 more sources
FIBRINOLYTIC AND ANTIFIBRINOLYTIC ACTIVITY IN PREGNANCY [PDF]
Journal of Clinical Pathology, 1960 Fibrinolytic activity and serum antifibrinolysin were estimated in normal pregnant women, during and after labour.The decreased fibrinolytic activity found during labour returned to non-pregnant levels within 24 hours of delivery. During the same period, the serum antifibrinolysin was rapidly diminished.It is suggested that the post-partum increase in ...
Sindhuja Naidoo, M. Hathorn, T Gillman
openalex +4 more sources
Antifibrinolytics in liver surgery
Indian Journal of Anaesthesia, 2010 Hyperfibrinolysis, a known complication of liver surgery and orthotopic liver transplantation (OLT), plays a significant role in blood loss. This fact justifies the use of antifibrinolytic drugs during these procedures.
Jalpa Makwana +2 more
doaj +4 more sources
Fibrinolytics and Antifibrinolytics. [PDF]
JAMA: The Journal of the American Medical Association, 1979 This large volume on various aspects of fibrinolytics and antifibrinolytics is the composite work of 18 collaborators primarily from several countries in Europe. Its aim is to present more information about these substances and to make the various concepts regarding their mode of activity available not only to the research workers in the field of ...
openalex +3 more sources
PLoS ONE, 2015 BackgroundRoutine use of antifibrinolytic agents in spine surgery is still an issue of debate.ObjectiveTo gather scientific evidence for the efficacy and safety of antifibrinolytic agents including aprotinin, tranexamic acid (TXA) and epsilon ...
Meng Wang +2 more
doaj +2 more sources
Efficacy and safety of using antifibrinolytic agents in spine surgery: a meta-analysis. [PDF]
PLoS ONE, 2013 PURPOSE: Spine surgery, particularly reconstructive surgery, can be associated with significant blood loss, and blood transfusion. Antifibrinolytic agents are used routinely to reduce bleeding in cardiac, orthopaedic, and hepatic surgery.
Chaoqun Yuan, Hailong Zhang, Shisheng He
doaj +2 more sources
The safety and efficacy of antifibrinolytic therapy in neonatal cardiac surgery. [PDF]
PLoS ONE, 2015 Neonates undergoing open-heart surgery are particularly at risk of postoperative bleeding requiring blood transfusion. Aprotinin has attained high efficacy in reducing the requirement for a blood transfusion following a cardiopulmonary bypass, but is ...
Chih-Yuan Lin +6 more
doaj +2 more sources
Antifibrinolytic Therapy and Perioperative Considerations [PDF]
Anesthesiology, 2018 Abstract Fibrinolysis is a physiologic component of hemostasis that functions to limit clot formation. However, after trauma or surgery, excessive fibrinolysis may contribute to coagulopathy, bleeding, and inflammatory responses. Antifibrinolytic agents are increasingly used to reduce bleeding, allogeneic blood administration, and adverse ...
Andreas Koster +4 more
openaire +4 more sources