Safety and Efficacy of Hospital Utilization of Tranexamic Acid in Civilian Adult Trauma Resuscitation [PDF]
, 2020 Introduction: Patients with trauma-induced coagulopathies may benefit from the use of antifibrinolytic agents, such as tranexamic acid (TXA). This study evaluated the safety and efficacy of TXA in civilian adults hospitalized with traumatic hemorrhagic ...
Borger, Rodney +13 more
core
Disseminated intravascular and intracardiac thrombosis after cardiopulmonary bypass
Journal of Anaesthesiology Clinical Pharmacology, 2017 Massive intracardiac and intravascular thrombosis is a rare complication following cardiopulmonary bypass (CPB). Most of the cases of the disseminated thrombosis have been reported in patients undergoing complex cardiac surgeries and those receiving ...
Deepak K Tempe +4 more
doaj +1 more source
Asian Journal of Medical Sciences, 2020 Tranexamic acid is widely used as an antifibrinolytic drug to reduce blood loss intraoperative and postoperative time periods as well as to reduce transfusion of allogeneic blood.
Indra K. Shrestha +2 more
doaj +1 more source
Plasmin Inhibitor in Health and Diabetes: Role of the Protein as a Therapeutic Target
TH Open, 2022 The vascular obstructive thrombus is composed of a mesh of fibrin fibers with blood cells trapped in these networks. Enhanced fibrin clot formation and/or suppression of fibrinolysis are associated with an increased risk of vascular occlusive events ...
Basmah Alsayejh +6 more
doaj +1 more source
Management of dental extraction in patients with Haemophilia A and B: a report of 58 extractions [PDF]
, 2014 Objectives: Patients with inherited bleeding disorders are at high risk of bleeding following oral surgery and present challenges to the oral surgeons. Aim of this study was to report our experience in dental extraction in patients exhibiting Haemophilia
Peisker, Andre +2 more
core +1 more source
40. The Benefits of Antifibrinolytic Administration in Minimally Invasive Craniosynostosis Repair [PDF]
Plastic and Reconstructive Surgery, Global OpenGabrielle C. Rodriguez, MD +8 more
doaj +2 more sources
Tranexamic acid therapy in pediatric cardiac surgery:a single center study [PDF]
, 2012 Background: We conducted a retrospective study of cyanotic and acyanotic patients undergoing cardiopulmonary bypass to determine the effect of tranexamic acid on blood loss and blood products administered during the operation in pediatric cardiac surgery.
Cioffi S +8 more
core +1 more source
Perioperative hyperfibrinolysis – physiology and pathophysiology
Brazilian Journal of Anesthesiology, 2021 Introduction and objectives: The role of the anesthesiologist in the perioperative management of hemostasis has attracted increasing attention. The fibrinolytic system participates in hemostasis, removing clots after repair of the vascular injury.
David Silveira Marinho
doaj +1 more source
Bernard-Soulier Syndrome: Identification of a Novel GP1BB Variant in a Mauritanian Patient. [PDF]
Mol Genet Genomic MedThis study identifies a new mutation of the GP1BB gene responsible for Bernard‐Soulier syndrome in a Mauritanian patient. Genetic analysis reveals a nucleotide duplication resulting in a severe platelet adhesion defect. This work highlights the importance of molecular diagnosis and therapeutic strategies to improve the management of affected patients ...
Salem ML, Zein E, Mohamed GS.
europepmc +2 more sources
Effect of oral tranexamic acid on macular edema associated with retinal vein occlusion or diabetes [PDF]
, 2017 Purpose: Tranexamic acid (TXA) is a widely used antifibrinolytic agent that can also cause a decrease in vascular permeability. We hypothesized that TXA could improve macular edema (ME) that is caused by an increase in retinal vascular permeability.
Gosho Masahiko +7 more
core +3 more sources