Results 31 to 40 of about 8,320 (205)
Asian Journal of Medical Sciences, 2020 Tranexamic acid is widely used as an antifibrinolytic drug to reduce blood loss intraoperative and postoperative time periods as well as to reduce transfusion of allogeneic blood.
Indra K. Shrestha +2 more
doaj +1 more source
Plasmin Inhibitor in Health and Diabetes: Role of the Protein as a Therapeutic Target
TH Open, 2022 The vascular obstructive thrombus is composed of a mesh of fibrin fibers with blood cells trapped in these networks. Enhanced fibrin clot formation and/or suppression of fibrinolysis are associated with an increased risk of vascular occlusive events ...
Basmah Alsayejh +6 more
doaj +1 more source
Fast selection of nonlinear mixed effect models using penalized likelihood [PDF]
arXiv, 2021 Nonlinear Mixed effects models are hidden variables models that are widely used in many fields such as pharmacometrics. In such models, the distribution characteristics of hidden variables can be specified by including several parameters such as covariates or correlations which must be selected.
arxiv
Antifibrinolytic role of a bee venom serine protease inhibitor that acts as a plasmin inhibitor. [PDF]
PLoS ONE, 2012 Bee venom is a rich source of pharmacologically active substances. In this study, we identified a bumblebee (Bombus ignitus) venom Kunitz-type serine protease inhibitor (Bi-KTI) that acts as a plasmin inhibitor.
Young Moo Choo +7 more
doaj +1 more source
Pharmaceutics, 2020 Antifibrinolytic site-specific pharmaco-laser therapy (SSPLT) is an experimental treatment modality for refractory port wine stains (PWS). Conceptually, antifibrinolytic drugs encapsulated in thermosensitive liposomes are delivered to thrombi that form ...
Mingjuan Li +10 more
doaj +1 more source
Türk Biyokimya Dergisi, 2022 Studies have shown that fibrinolysis activity is insufficient in COVID-19 patients. Plasminogen activator inhibitor-1 (PAI-1) is an important antifibrinolytic molecule that plays a key role in the fibrinolytic system.
Baltan Ecem +4 more
doaj +1 more source
Impact of aprotinin and renal function on mortality: a retrospective single center analysis
Journal of Cardiothoracic Surgery, 2011 Background An estimated up to 7% of high-risk cardiac surgery patients return to the operating room for bleeding. Aprotinin was used extensively as an antifibrinolytic agent in cardiac surgery patients for over 15 years and it showed efficacy in reducing
Von Visger Jon +6 more
doaj +1 more source
Inducing emesis in Australian dogs and cats: agents, adverse effects and antiemetic administration
Australian Veterinary Journal, EarlyView.Objective To describe the agents used by Australian veterinarians in inducing emesis in dogs and cats, adverse effects and antiemetic administration. Methods An anonymous online mixed‐methods survey incorporating closed and open‐ended questions was distributed to Australian veterinarians via e‐newsletters and social media between April and June 2024 ...
J Tsitonakis, E Hall, A Quain
wiley +1 more source
Diabetes, Obesity and Metabolism, EarlyView.Abstract Lipoprotein(a) [Lp(a)] is a genetically determined, causal risk factor for atherosclerotic cardiovascular disease (ASCVD) and calcific aortic valve disease (CAVD). Despite robust evidence from epidemiological and genetic studies, Lp(a) remains underrecognised in clinical practice due to challenges in measurement, lack of guideline familiarity ...
Alexander C. Razavi +4 more
wiley +1 more source
Antifibrinolytic agents for the prevention of postpartum hemorrhage
Thrombosis Update, 2021 Acute obstetric coagulopathy secondary to postpartum hemorrhage (PPH) is associated with poor outcome. There is evidence that Tranexamic Acid (TA), an antifibrinolytic drug, is an efficient tool of patient blood management in association with uterotonics
Anne-Sophie Bouthors +3 more
doaj