Results 31 to 40 of about 6,662 (219)
The safety and efficacy of antifibrinolytic therapy in neonatal cardiac surgery. [PDF]
PLoS ONE, 2015 Neonates undergoing open-heart surgery are particularly at risk of postoperative bleeding requiring blood transfusion. Aprotinin has attained high efficacy in reducing the requirement for a blood transfusion following a cardiopulmonary bypass, but is ...
Chih-Yuan Lin +6 more
doaj +1 more source
Abdominal trauma in dogs 2. management [PDF]
, 2018 Trauma represents a big challenge for emergency doctors both in human and veterinary medicine. There have been great advancements in trauma medicine in people and these often provide an inspiration for veterinary surgeons.
Cortellini, S, Humm, K R
core +1 more source
Aprotinin reduces cardiac troponin I release and inhibits apoptosis of polymorphonuclear cells during off-pump coronary artery bypass surgery [PDF]
, 2008 Objectives: In addition to blood-sparing effects, aprotinin may have cardioprotective and anti-inflammatory effects during cardiopulmonary bypass-assisted cardiac surgery.
Bert, C. +9 more
core +2 more sources
PLoS ONE, 2015 BackgroundRoutine use of antifibrinolytic agents in spine surgery is still an issue of debate.ObjectiveTo gather scientific evidence for the efficacy and safety of antifibrinolytic agents including aprotinin, tranexamic acid (TXA) and epsilon ...
Meng Wang +2 more
doaj +1 more source
Antifibrinolytic drugs for acute traumatic injury [PDF]
São Paulo Medical Journal, 2011 Uncontrolled bleeding is an important cause of death in trauma victims. Antifibrinolytic treatment has been shown to reduce blood loss following surgery and may also be effective in reducing blood loss following trauma.To assess the effect of antifibrinolytic drugs in patients with acute traumatic injury.We ran the most recent search in January 2015 ...
Ian Roberts +3 more
doaj +11 more sources
Asian Journal of Medical Sciences, 2020 Tranexamic acid is widely used as an antifibrinolytic drug to reduce blood loss intraoperative and postoperative time periods as well as to reduce transfusion of allogeneic blood.
Indra K. Shrestha +2 more
doaj +1 more source
Plasmin Inhibitor in Health and Diabetes: Role of the Protein as a Therapeutic Target
TH Open, 2022 The vascular obstructive thrombus is composed of a mesh of fibrin fibers with blood cells trapped in these networks. Enhanced fibrin clot formation and/or suppression of fibrinolysis are associated with an increased risk of vascular occlusive events ...
Basmah Alsayejh +6 more
doaj +1 more source
Disseminated intravascular and intracardiac thrombosis after cardiopulmonary bypass
Journal of Anaesthesiology Clinical Pharmacology, 2017 Massive intracardiac and intravascular thrombosis is a rare complication following cardiopulmonary bypass (CPB). Most of the cases of the disseminated thrombosis have been reported in patients undergoing complex cardiac surgeries and those receiving ...
Deepak K Tempe +4 more
doaj +1 more source
Safety and Efficacy of Hospital Utilization of Tranexamic Acid in Civilian Adult Trauma Resuscitation [PDF]
, 2020 Introduction: Patients with trauma-induced coagulopathies may benefit from the use of antifibrinolytic agents, such as tranexamic acid (TXA). This study evaluated the safety and efficacy of TXA in civilian adults hospitalized with traumatic hemorrhagic ...
Borger, Rodney +13 more
core
Tranexamic acid therapy in pediatric cardiac surgery:a single center study [PDF]
, 2012 Background: We conducted a retrospective study of cyanotic and acyanotic patients undergoing cardiopulmonary bypass to determine the effect of tranexamic acid on blood loss and blood products administered during the operation in pediatric cardiac surgery.
Cioffi S +8 more
core +1 more source