Results 41 to 50 of about 8,320 (205)

Plasma‐Derived von Willebrand Factor/Factor VIII Concentrate (Haemate P) in von Willebrand Disease: A Systematic Review and Pharmacovigilance Update

open access: yesHaemophilia, Volume 31, Issue 2, Page 247-262, March 2025.
ABSTRACT Background Von Willebrand disease (VWD) is an inherited bleeding disorder caused by deficient or dysfunctional von Willebrand factor (VWF). VWF replacement therapy is indicated in VWD management. Methods This systematic review was conducted to evaluate all available evidence of the efficacy, safety, dosing and consumption of pasteurized plasma‐
Carmen Escuriola Ettingshausen   +6 more
wiley   +1 more source

Inhibitor Eradication in Postpartum Acquired Haemophilia A: Real‐Life Case Series and Literature Review

open access: yesHaemophilia, EarlyView.
ABSTRACT Background Acquired haemophilia A (AHA) is a rare and severe bleeding disorder generally associated with pregnancy or aging. Spontaneous remission and prompt inhibitor eradication are described more frequently in postpartum cases. We evaluated retrospectively 15 postpartum AHA cases between 2007 and 2023 in order to evaluate response in terms ...
Gaetano Giuffrida   +14 more
wiley   +1 more source

Integration of clinical parameters, genotype and epistaxis severity score to guide treatment for hereditary hemorrhagic telangiectasia associated bleeding

open access: yesOrphanet Journal of Rare Diseases, 2020
Background Hereditary Hemorrhagic Telangiectasia (HHT) is a rare inherited disorder characterized by development of mucocutaneous telangiectases and visceral organ arteriovenous malformations, which can lead to recurrent, spontaneous bleeding and ...
Joan D. Beckman   +5 more
doaj   +1 more source

Obstetric and Gynaecological Challenges and Outcomes in Women and Girls With Glanzmann's Thrombasthenia

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Glanzmann's thrombasthenia (GT) is an inherited platelet function disorder that may manifest with significant bleeding symptoms; in women and girls (W&Gs), heavy menstrual bleeding (HMB) is very common. GT in pregnancy is associated with an increased risk of postpartum haemorrhage (PPH).
Deborah Obeng‐Tuudah   +3 more
wiley   +1 more source

The use of fibrinolysis inhibitors in cardiac surgery with cardiopulmonary bypass (literature review)

open access: yesВестник анестезиологии и реаниматологии
In cardiac surgery with cardiopulmonary bypass (CPB) is a common complication. The incidence of this complication in cardiac surgery patients is estimated at about 10%.
V. Yu. Medvedeva   +3 more
doaj   +1 more source

The Effect of Tranexamic Acid (Cyclokapron) on Post–Surgical Bleeding Following the Removal of Impacted Lower Wisdom Teeth in Healthy Individuals [PDF]

open access: yesAl-Rafidain Dental Journal, 2008
Aims: To evaluate the effect of local irrigation with tranexamic acid in minimizing post–operative bleeding following the removal of impacted lower wisdom teeth.
Rayan S. Hamid   +2 more
doaj   +1 more source

Subarachnoid lavage following inadvertent intrathecal injection of tranexamic acid

open access: yesIbom Medical Journal, 2022
Tranexamic acid (TXA) is a commonly used antifibrinolytic drug during surgical procedures to reduce blood loss. An Inadvertent intrathecal injection of TXA may lead to serious side effects including seizures and ventricular fibrillation with reported ...
Salahu D   +16 more
doaj   +1 more source

Freeze‐dried plasma: Hemostasis and biophysical analyses for damage control resuscitation

open access: yesTransfusion, Volume 65, Issue S1, Page S250-S264, May 2025.
Abstract Background Effective hemorrhage protocols prioritize immediate hemostatic resuscitation to manage hemorrhagic shock. Prehospital resuscitation using blood products, such as whole blood or alternatively dried plasma in its absence, has the potential to improve outcomes in hemorrhagic shock patients.
Aron A. Shoara   +16 more
wiley   +1 more source

Management challenge of a rare concomitant platelet glycoprotein IV/CD36 and IIb/IIIa deficiencies: Case illustration

open access: yesTransfusion, Volume 65, Issue 4, Page 767-772, April 2025.
Abstract Introduction/Background Platelet membrane glycoproteins (GPs) serve several functions, the most significant of which is their role in primary hemostasis. Among these, GP IIb/IIIa is the primary fibrinogen receptor and is essential for platelet aggregation.
Tro Sekayan   +8 more
wiley   +1 more source

CM352 Reduces Brain Damage and Improves Functional Recovery in a Rat Model of Intracerebral Hemorrhage

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundIntracerebral hemorrhage (ICH) is an acute neurological disorder with high mortality and no effective treatment. In addition to the initial bleeding event, rebleeding and hematoma expansion are associated with poor outcome in these patients. We
José A. Rodríguez   +11 more
doaj   +1 more source

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