Results 51 to 60 of about 18,529 (289)

Abdominal trauma in dogs 2. management [PDF]

, 2018
Trauma represents a big challenge for emergency doctors both in human and veterinary medicine. There have been great advancements in trauma medicine in people and these often provide an inspiration for veterinary surgeons.
Cortellini, S, Humm, K R
core   +1 more source

Tranexamic Acid in Civilian Trauma Care in the California Prehospital Antifibrinolytic Therapy Study

Western Journal of Emergency Medicine, 2018
Introduction Hemorrhage is one of the leading causes of death in trauma victims. Historically, paramedics have not had access to medications that specifically target the reversal of trauma-induced coagulopathies.
M. Neeki, F. Dong, Jake Toy, Reza Vaezazizi, J. Powell, David Wong, Michael Mousselli, Massoud Rabiei, A. Jabourian, N. Niknafs, M. Burgett-Moreno, Richard Vara, S. Kissel, X. Luo-Owen, Karen R. O’Bosky, Daniel Ludi, K. Sporer, Troy W. Pennington, Tommy Lee, R. Borger, Eugene Kwong   +20 more
semanticscholar   +1 more source

Role of tranexamic acid to reduce blood loss and transfusion of allogeneic blood in the field of surgery

Asian Journal of Medical Sciences, 2020
Tranexamic acid is widely used as an antifibrinolytic drug to reduce blood loss intraoperative and postoperative time periods as well as to reduce transfusion of allogeneic blood.
Indra K. Shrestha , Yong Yu Si , Jian Ping Tao   +2 more
doaj   +1 more source

Plasmin Inhibitor in Health and Diabetes: Role of the Protein as a Therapeutic Target

TH Open, 2022
The vascular obstructive thrombus is composed of a mesh of fibrin fibers with blood cells trapped in these networks. Enhanced fibrin clot formation and/or suppression of fibrinolysis are associated with an increased risk of vascular occlusive events ...
Basmah Alsayejh, Noppadol Kietsiriroje, Mansour Almutairi, Katie Simmons, Nikoletta Pechlivani, Sreenivasan Ponnambalam, Ramzi A. Ajjan   +6 more
doaj   +1 more source

Disseminated intravascular and intracardiac thrombosis after cardiopulmonary bypass

Journal of Anaesthesiology Clinical Pharmacology, 2017
Massive intracardiac and intravascular thrombosis is a rare complication following cardiopulmonary bypass (CPB). Most of the cases of the disseminated thrombosis have been reported in patients undergoing complex cardiac surgeries and those receiving ...
Deepak K Tempe, Parin Lalwani, Kapil Chaudhary, Harpreet S Minas, Akhlesh S Tomar   +4 more
doaj   +1 more source

The impact of Cochrane Systematic Reviews : a mixed method evaluation of outputs from Cochrane Review Groups supported by the UK National Institute for Health Research [PDF]

, 2014
© 2014 Bunn et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and ...
A Boaz, A Coffey, A Jorgensen, AM Moseley, C Ham, C Weiss, CE Estabrooks, CJ Cates, CJ Cates, CJ Cates, D Gillies, DL Sackett, E McInnes, European Medicines Agency, F Bunn, F Bunn, H Piwowar, HEFC, HT Martin, I Roberts, I Roberts, ID Cameron, J Burnett, J Comroe, J Grimshaw, J Grimshaw, J Lavis, J Lomas, J Ryan, JM Grimshaw, K Oliver, L Becker, L Thomas, LD Gillespie, LI Meho, M Buxton, M Dawes, M Gold, M Huberman, ME Falagas, N Black, O Olsen, P Lockhart, P Perel, P Perel, PA Sabatier, S Hanney, S Hanney, S Ismail, S Kuruvilla, S Kuruvilla, S Nutley, S Peckham, SE Cozzens, SR Hanney, TA Sheldon, TA Sheldon, TN van Leeuwen   +57 more
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Antifibrinolytic therapy for preventing oral bleeding in people on anticoagulants undergoing minor oral surgery or dental extractions.

Cochrane Database of Systematic Reviews, 2018
BACKGROUND Individuals on continuous treatment with vitamin K antagonists (VKAs) or direct oral anticoagulants (DOACs) are at increased risk of bleeding complications during and after oral or dental procedures.
E. T. Engelen, R. Schutgens, E. Mauser-Bunschoten, R. V. van Es, K. V. van Galen   +4 more
semanticscholar   +1 more source

Antifibrinolytic role of a bee venom serine protease inhibitor that acts as a plasmin inhibitor. [PDF]

PLoS ONE, 2012
Bee venom is a rich source of pharmacologically active substances. In this study, we identified a bumblebee (Bombus ignitus) venom Kunitz-type serine protease inhibitor (Bi-KTI) that acts as a plasmin inhibitor.
Young Moo Choo, Kwang Sik Lee, Hyung Joo Yoon, Yuling Qiu, Hu Wan, Mi Ri Sohn, Hung Dae Sohn, Byung Rae Jin   +7 more
doaj   +1 more source

Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients. [PDF]

, 2017
BACKGROUND: Antifibrinolytics reduce death from bleeding in trauma and post-partum haemorrhage. We examined the effect of treatment delay on the effectiveness of antifibrinolytics.
Ageron, François-Xavier, Antifibrinolytic Trials Collaboration, Gayet-Ageron, Angèle, Ker, Katharine, Prieto-Merino, David, Roberts, Ian, Shakur, Haleema   +6 more
core   +1 more source

Safety and Efficacy of Hospital Utilization of Tranexamic Acid in Civilian Adult Trauma Resuscitation [PDF]

, 2020
Introduction: Patients with trauma-induced coagulopathies may benefit from the use of antifibrinolytic agents, such as tranexamic acid (TXA). This study evaluated the safety and efficacy of TXA in civilian adults hospitalized with traumatic hemorrhagic ...
Borger, Rodney, Chandwani, Deepak, Comunale, Mark E., Dong, Fanglong, Inaba, Kenji, Lowe, Andrew, Neeki, Michael, Powell, Joe, Quispe, Juan, Rabiei, Massoud, Salameh, Joseph, Toy, Jake, Vara, Richard, Wong, David   +13 more
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