Results 61 to 70 of about 8,320 (205)
Hermansky‐Pudlak Syndrome: From Molecular Pathogenesis to Targeted Therapies
IUBMB Life, Volume 77, Issue 5, May 2025.ABSTRACT Hermansky‐Pudlak syndrome (HPS) is a rare inherited disorder caused by defects in lysosome‐related organelles (LROs) in various tissues, including platelets, melanocytes, and endothelial cells. Key features of HPS include oculocutaneous albinism, bleeding tendency, and, in some cases, pulmonary fibrosis, granulomatous colitis, and ...
Francesca Tondi +6 more
wiley +1 more source
Anti-fibrinolytic agents in post partum haemorrhage: a systematic review
BMC Pregnancy and Childbirth, 2009 Background Post partum haemorrhage is a leading cause of maternal death worldwide. It also contributes to maternal morbidity as women may require a hysterectomy to control bleeding, or may require a blood transfusion, which can transmit viral infections.
Blackhall Karen +4 more
doaj +1 more source
Transfusion, Volume 65, Issue S1, Page S173-S180, May 2025.Abstract Introduction Data regarding low titer group O whole blood (LTOWB) use for hemostatic resuscitation is largely derived from trauma cohorts; studies regarding its use in uninjured pediatric patients are lacking. Methods The blood bank database from a single academic pediatric hospital with a massive transfusion protocol (MTP) allowing the use of
Erin V. Feeney +4 more
wiley +1 more source
Predictive model for optimizing prehospital transfusions in an urban EMS system
Transfusion, Volume 65, Issue S1, Page S23-S29, May 2025.Abstract Background Prehospital transfusions might provide a survival benefit for injured patients. Because blood products are a scarce resource, their optimal deployment requires careful consideration. A computer model was built to explore different deployment scenarios for two blood‐carrying ambulances (mobile blood banks, MBBs) in the City of ...
Bo Zeng +6 more
wiley +1 more source
Perioperative hyperfibrinolysis – physiology and pathophysiology
Brazilian Journal of Anesthesiology, 2021 Introduction and objectives: The role of the anesthesiologist in the perioperative management of hemostasis has attracted increasing attention. The fibrinolytic system participates in hemostasis, removing clots after repair of the vascular injury.
David Silveira Marinho
doaj
MANAGEMENT OF THE HAEMOPHILIC PATIENT IN DENTISTRY AND CERVICOFACIAL SURGERY
Romanian Journal of Oral Rehabilitation, 2023 In patients with haemophilia, any oral surgery carries the risk of prolonged and excessive bleeding. Close collaboration between haematologists and oral surgeons is necessary to prevent excessive bleeding.
Lidia Cureniuc +11 more
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Asian Journal of Transfusion Science, 2008 Background: During orthotopic liver transplantation (OLT), activation of the fibrinolytic system can contribute significantly to perioperative bleeding.
Devi A +4 more
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Seizure induced by tranexamic acid in a patient with chronic kidney disease on maintenance dialysis
Saudi Journal of Kidney Diseases and Transplantation, 2018 Tranexamic acid (TXA) is an antifibrinolytic agent commonly used to achieve hemostasis. However, there have been a few case reports suggesting that high-dose intravenous TXA has epileptogenic property.
Kar Wah Fuah +3 more
doaj +1 more source
Allergy, Asthma & Clinical Immunology, 2010 Acquired angioedema (AAE) is characterized by acquired deficiency of C1 inhibitor (C1-INH), hyperactivation of the classical pathway of human complement and angioedema symptoms mediated by bradykinin released by inappropriate activation of the contact ...
Cicardi Marco, Zanichelli Andrea
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THE OCCURRENCE OF ANTIFIBRINOLYTIC PROPERTIES IN THE BLOOD OF PATIENTS WITH ACUTE HEMOLYTIC STREPTOCOCCUS INFECTIONS [PDF]
, 1935 William S. Tillett
openalex +1 more source