Characterization and management of patients with hereditary factor X deficiency: A case series
Transfusion, EarlyView.Abstract Background Hereditary factor X deficiency (HFXD) is an ultra‐rare, autosomal recessive bleeding disorder that results in reduced factor X coagulant activity (FX:C). HFXD is traditionally classified by severity as severe (FX:C <1%), moderate (FX:C = 1%–5%), or mild (FX:C = 6%–10%).
Meera Chitlur +4 more
wiley +1 more source
The Effect of Tranexamic Acid (Cyclokapron) on Post–Surgical Bleeding Following the Removal of Impacted Lower Wisdom Teeth in Healthy Individuals [PDF]
Al-Rafidain Dental Journal, 2008 Aims: To evaluate the effect of local irrigation with tranexamic acid in minimizing post–operative bleeding following the removal of impacted lower wisdom teeth.
Rayan S. Hamid +2 more
doaj +1 more source
Clinically Significant Thromboembolic Disease in Adult Spinal Deformity Surgery: Incidence and Risk Factors in 737 Patients. [PDF]
, 2017 Study Design:Retrospective cohort study. Objectives:Describe the rate and risk factors for venous thromboembolic events (VTEs; defined as deep venous thrombosis [DVT] and/or pulmonary embolism [PE]) in adult spinal deformity (ASD) surgery.
Bess, Shay +14 more
core +1 more source
American Journal of Hematology, Volume 100, Issue 10, Page 1813-1827, October 2025.ABSTRACT Hereditary hemorrhagic telangiectasia (HHT, Osler‐Weber‐Rendu disease) is the second most common inherited bleeding disorder worldwide, affecting approximately 1 in 5000 people. Development of disease‐modifying and efficacious hemostatic agents to treat HHT has finally begun after decades without such medical therapies.
Hanny Al‐Samkari +22 more
wiley +1 more source
Spontaneous gastrocnemius muscle haematoma formation in a patient with alcoholic liver disease
The Pan African Medical Journal, 2020 Advanced liver disease is associated with several haemostatic alterations which can lead to either thrombosis or bleeding complications. Spontaneous muscle haematomas although a rare complication of liver cirrhosis is increasingly being described in the ...
Ndawapeka Tulonga Nhinda +3 more
doaj +1 more source
Applying results from clinical trials: tranexamic acid in trauma patients. [PDF]
, 2014 This paper considers how results from clinical trials should be applied in the care of patients, using the results of the Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage (CRASH-2) trial of tranexamic acid in bleeding trauma ...
Prieto-Merino, David, Roberts, Ian
core +1 more source
Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients. [PDF]
, 2017 BACKGROUND: Antifibrinolytics reduce death from bleeding in trauma and post-partum haemorrhage. We examined the effect of treatment delay on the effectiveness of antifibrinolytics.
Ageron, François-Xavier +6 more
core +1 more source
Ferroptosis in Cancer and Inflammatory Diseases: Mechanisms and Therapeutic Implications
MedComm, Volume 6, Issue 9, September 2025.Ferroptosis, a form of cell death driven by iron and lipid peroxidation, serves as a bridge between cancer and inflammatory diseases. Microenvironmental factors such as oxidative stress collectively regulate this process. In cancer, ferroptosis exhibits dual roles: while it eliminates drug‐resistant cells, it may also promote tumor metastasis.
Guangyi Shen +4 more
wiley +1 more source
Anti-fibrinolytic agents in post partum haemorrhage: a systematic review
BMC Pregnancy and Childbirth, 2009 Background Post partum haemorrhage is a leading cause of maternal death worldwide. It also contributes to maternal morbidity as women may require a hysterectomy to control bleeding, or may require a blood transfusion, which can transmit viral infections.
Blackhall Karen +4 more
doaj +1 more source
Otolaryngology–Head and Neck Surgery, Volume 173, Issue 3, Page 745-753, September 2025.Abstract Objective Evaluate the use of tranexamic acid (TXA) and observation as a management option for pediatric patients presenting with posttonsillectomy hemorrhage (PTH). Study Design Retrospective analysis of a prospectively implemented quality improvement initiative with a historical control comparison group. Setting Tertiary children's hospital.
Laura A. Petrauskas +12 more
wiley +1 more source