Results 81 to 90 of about 18,529 (289)

Antifibrinolytic Therapy for Cardiac Surgery: An Update.

open access: yesAnesthesiology, 2015
214 July 2015 I N cardiac surgery, antifibrinolytic agents, including aprotinin and lysine analogs (ε-aminocaproic acid [EACA] and tranexamic acid [TXA]), have been extensively studied, and they decrease hemostatic activation, reduce bleeding, and ...
A. Koster, D. Faraoni, J. Levy
semanticscholar   +1 more source

Integration of clinical parameters, genotype and epistaxis severity score to guide treatment for hereditary hemorrhagic telangiectasia associated bleeding

open access: yesOrphanet Journal of Rare Diseases, 2020
Background Hereditary Hemorrhagic Telangiectasia (HHT) is a rare inherited disorder characterized by development of mucocutaneous telangiectases and visceral organ arteriovenous malformations, which can lead to recurrent, spontaneous bleeding and ...
Joan D. Beckman   +5 more
doaj   +1 more source

Fabricating Microfluidic Co‐Cultures of Immortalized Cell Lines Uncovers Robust Design Principles for the Simultaneous Formation of Patterned, Vascularized, and Stem Cell‐Derived Adipose Tissue

open access: yesSmall, EarlyView.
Murphy et al present an optimized co‐culture protocol for immortalized cell line vasculogenesis. Here, immortalized co‐cultures form reproducible microvessel networks across 31‐days, while gradient microchips enable simultaneous mesenchymal stem cell (MSC) adipogenesis and endothelial cell (EC) vasculogenesis.
Ashley R. Murphy   +2 more
wiley   +1 more source

Hemostatic effects of tranexamic acid in elective thoracic aortic surgery: A prospective, randomized, double-blind, placebo-controlled study [PDF]

open access: yes, 2002
Objective: We studied the hemostatic effects of tranexamic acid in patients undergoing elective surgery involving the thoracic aorta. Methods: In a double-blind, randomized fashion, 60 consecutive patients were assigned to two treatment groups: 30 ...
Calori, Giliola   +5 more
core   +1 more source

Is it time to offer routine screening for iron deficiency in healthy adolescent females?

open access: yesBritish Journal of Haematology, EarlyView.
Given the high prevalence of iron deficiency (ID) in adolescents and the significant health consequences it entails, we recommend screening all female adolescents for ID using serum haemoglobin and ferritin, starting at age 14–15 (approximately 3 years post‐menarche) and repeating every 5 years.
Shoshana Revel‐Vilk   +2 more
wiley   +1 more source

Subarachnoid lavage following inadvertent intrathecal injection of tranexamic acid

open access: yesIbom Medical Journal, 2022
Tranexamic acid (TXA) is a commonly used antifibrinolytic drug during surgical procedures to reduce blood loss. An Inadvertent intrathecal injection of TXA may lead to serious side effects including seizures and ventricular fibrillation with reported ...
Salahu D   +16 more
doaj   +1 more source

Topical use of tranexamic acid in coronary artery bypass operations: A double-blind, prospective, randomized, placebo-controlled study [PDF]

open access: yes, 2000
Objectives: We sought to investigate the effect of topical application of tranexamic acid into the pericardial cavity in reducing postoperative blood loss in coronary artery surgery.
Alessandrini, Francesco   +7 more
core   +1 more source

Why, how and in whom should we measure levels of lipoprotein(a): A review of the latest evidence and clinical implications

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Lipoprotein(a) [Lp(a)] is a genetically determined, causal risk factor for atherosclerotic cardiovascular disease (ASCVD) and calcific aortic valve disease (CAVD). Despite robust evidence from epidemiological and genetic studies, Lp(a) remains underrecognised in clinical practice due to challenges in measurement, lack of guideline familiarity ...
Alexander C. Razavi   +4 more
wiley   +1 more source

The use of fibrinolysis inhibitors in cardiac surgery with cardiopulmonary bypass (literature review)

open access: yesВестник анестезиологии и реаниматологии
In cardiac surgery with cardiopulmonary bypass (CPB) is a common complication. The incidence of this complication in cardiac surgery patients is estimated at about 10%.
V. Yu. Medvedeva   +3 more
doaj   +1 more source

The Effect of Tranexamic Acid (Cyclokapron) on Post–Surgical Bleeding Following the Removal of Impacted Lower Wisdom Teeth in Healthy Individuals [PDF]

open access: yesAl-Rafidain Dental Journal, 2008
Aims: To evaluate the effect of local irrigation with tranexamic acid in minimizing post–operative bleeding following the removal of impacted lower wisdom teeth.
Rayan S. Hamid   +2 more
doaj   +1 more source

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