Results 91 to 100 of about 7,481 (249)

Effect of Prophylactic Intravenous Tranexamic Acid on Blood Loss After Vaginal Delivery: A Randomized Control Study

Health Science Reports
Background and Aim To determine the effect of prophylactic intravenous tranexamic acid on blood loss after vaginal delivery in women at low risk of postpartum hemorrhage.
Sajana Shrestha, Shelisha Uprety, Ravi Shah, Brinda Kharel   +3 more
doaj   +1 more source

Potent reduction of plasma lipoprotein (a) with an antisense oligonucleotide in human subjects does not affect ex vivo fibrinolysis

Journal of Lipid Research, 2019
It is postulated that lipoprotein (a) [Lp(a)] inhibits fibrinolysis, but this hypothesis has not been tested in humans due to the lack of specific Lp(a) lowering agents. Patients with elevated Lp(a) were randomized to antisense oligonucleotide [IONIS-APO(
Michael B. Boffa, Tanya T. Marar, Calvin Yeang, Nicholas J. Viney, Shuting Xia, Joseph L. Witztum, Marlys L. Koschinsky, Sotirios Tsimikas   +7 more
doaj   +1 more source

Postoperative bilateral visual loss after a single dose of tranexamic acid

Anaesthesia Reports, Volume 13, Issue 2, July‐December 2025.
Summary A 32‐year‐old woman presented with transient visual loss following the intra‐operative administration of a single intravenous dose of tranexamic acid during urgent cholecystectomy. Apart from obesity, the patient had no notable medical history or pre‐existing ocular conditions.
B. Chevalley, M. Betello, E. Blavakis, A. Malclès, J. Maillard   +4 more
wiley   +1 more source

Progress on hematoma expansion mechanism and hemostatic therapy of spontaneous intracerebral hemorrhage

Chinese Journal of Contemporary Neurology and Neurosurgery, 2021
Spontaneous intracerebral hemorrhage (SICH) is a severe subtype of stroke. Hematoma expansion could occur in the short term after symptom onset in most patients, leading to neurological deterioration and mortality.
LI Yu⁃jian, ZHENG Jun
doaj  

Treatment Landscape in Pediatric Immune Thrombocytopenia: Addressing Unmet Needs

Pediatric Blood &Cancer, Volume 72, Issue 7, July 2025.
ABSTRACT Pediatric immune thrombocytopenia (ITP) is associated with a multifaceted burden on children and their parents/caregivers due to bleeding, fatigue, activity restrictions, and psychological distress. Most children recover within 12 months, but up to 30% develop chronic ITP.
Joana Azevedo, Jennifer DiRaimo, Cindy Neunert, Nichola Cooper, Rachael F. Grace   +4 more
wiley   +1 more source

Topical vs. intravenous administration of tranexamic acid in knee arthroplasty and prevalence of deep venous thrombosis: a randomized clinical trial

Jornal Vascular Brasileiro
Background Tranexamic acid (TXA) is widely used in orthopedic surgery to reduce perioperative bleeding. Since TXA inhibits fibrinolysis, there is concern that it may increase the risk of thromboembolic events. Objectives To verify the prevalence of deep
Ari Zekcer, Ricardo Del Priori, Clauber Tieppo, Ricardo Soares da Silva, Nilson Roberto Severino   +4 more
doaj   +1 more source

Antifibrinolíticos e cirurgia cardíaca com circulação extracorpórea Antifibrinolíticos y cirugía cardíaca con circulación extracorpórea Antifibrinolytics and cardiac surgery with cardiopulmonary bypass

Revista Brasileira de Anestesiologia, 2007
JUSTIFICATIVA E OBJETIVOS: A cirurgia cardíaca é a especialidade cirúrgica que com mais freqüência está associada a sangramento, coagulopatia e necessidade de derivados de sangue.
Ari-Tadeu Lírio dos Santos, João Carlos Splettstosser, Paulo Warpechowski, Mariana Mariz Pinto Gaidzinski   +3 more
doaj   +1 more source

Promise, Pitfalls, and Precision: Standardizing Clinical Framework for Hereditary Hemorrhagic Telangiectasia and a Call for Cost‐Conscious Innovation

American Journal of Hematology, Volume 100, Issue 10, Page 1719-1721, October 2025.
Magdalena Lewandowska
wiley   +1 more source

Inducing emesis in Australian dogs and cats: agents, adverse effects and antiemetic administration

Australian Veterinary Journal, Volume 103, Issue 7, Page 433-442, July 2025.
Objective To describe the agents used by Australian veterinarians in inducing emesis in dogs and cats, adverse effects and antiemetic administration. Methods An anonymous online mixed‐methods survey incorporating closed and open‐ended questions was distributed to Australian veterinarians via e‐newsletters and social media between April and June 2024 ...
J Tsitonakis, E Hall, A Quain
wiley   +1 more source

Plasminflammation—An Emerging Pathway to Bradykinin Production

Frontiers in Immunology, 2019
Plasminogen activation is essential for fibrinolysis—the breakdown of fibrin polymers in blood clots. Besides this important function, plasminogen activation participates in a wide variety of inflammatory conditions. One of these conditions is hereditary
Coen Maas
doaj   +1 more source