Results 91 to 100 of about 54,087 (251)
Lytic and mechanical stability of clots composed of fibrin and blood vessel wall components. [PDF]
Background Proteases expressed in atherosclerotic plaque lesions generate collagen fragments, release glycosaminoglycans (chondroitin sulfate [CS] and dermatan sulfate [DS]) and expose extracellular matrix (ECM) proteins (e.g.
Bóta, Attila+7 more
core +1 more source
Perioperative hyperfibrinolysis – physiology and pathophysiology
Introduction and objectives: The role of the anesthesiologist in the perioperative management of hemostasis has attracted increasing attention. The fibrinolytic system participates in hemostasis, removing clots after repair of the vascular injury.
David Silveira Marinho
doaj
ABSTRACT Despite therapeutic advances, people with hemophilia experience bleeds. These may be life‐threatening, result in permanent joint damage, chronic pain, difficulties with mobility/daily activities, and impact quality of life. In the XTEND‐1 study (NCT04161495), once‐weekly efanesoctocog alfa (50 IU/kg) prophylaxis provided highly effective bleed
Angela C. Weyand+7 more
wiley +1 more source
OBJETIVO: Verificar o efeito do uso tópico do ácido epsilon-aminocapróico (AEAC), aplicado na cavidade pericárdica, na redução do sangramento e necessidade de transfusão sanguínea no pós-operatório de revascularização cirúrgica do miocárdio.
João Roberto Breda+7 more
doaj +1 more source
Preventive and therapeutic effects of tranexamic acid on postpartum bleeding [PDF]
Postpartum hemorrhage is among the leading causes of maternal mortality throughout the world. Severe blood loss contributes to the increased blood transfusion risk with its concerned inherent adverse events and therefore increased rate of emergency re ...
Samaneh Solltani+3 more
doaj +1 more source
Hermansky‐Pudlak Syndrome: From Molecular Pathogenesis to Targeted Therapies
ABSTRACT Hermansky‐Pudlak syndrome (HPS) is a rare inherited disorder caused by defects in lysosome‐related organelles (LROs) in various tissues, including platelets, melanocytes, and endothelial cells. Key features of HPS include oculocutaneous albinism, bleeding tendency, and, in some cases, pulmonary fibrosis, granulomatous colitis, and ...
Francesca Tondi+6 more
wiley +1 more source
Re-Evaluation of the Role of Antifibrinolytic Therapy with Lysine Analogs in Liver Transplantation in The Post-Aprotinin Era [PDF]
Purpose of review: Hemorrhage, blood and blood product transfusions and the need for surgical re-exploration for bleeding can have a detrimental effect on patient outcome during liver surgery.
CONIGLIONE, FILADELFO+9 more
core +2 more sources
Approach to Hemoptysis in the Modern Era
Hemoptysis is a frequent manifestation of a wide variety of diseases, with mild to life-threatening presentations. The diagnostic workup and the management of severe hemoptysis are often challenging.
Sébastien Gagnon+4 more
doaj +1 more source
Fibrinolysis and bleeding of unknown cause
Patients with bleeding of unknown cause (BUC) present with a variety of mild to moderate bleeding symptoms, but no hemostatic abnormalities can be found. Hyperfibrinolysis is rarely evaluated as the underlying cause for bleeding in clinical practice, and
Dino Mehic+3 more
doaj +1 more source
On Networks with Active and Passive Agents [PDF]
We introduce an active-passive networked multiagent system framework, which consists of agents subject to exogenous inputs (active agents) and agents without any inputs (passive agents), and analyze its convergence using Lyapunov stability.
arxiv