Results 91 to 100 of about 54,087 (251)

Lytic and mechanical stability of clots composed of fibrin and blood vessel wall components. [PDF]

open access: yes, 2013
Background Proteases expressed in atherosclerotic plaque lesions generate collagen fragments, release glycosaminoglycans (chondroitin sulfate [CS] and dermatan sulfate [DS]) and expose extracellular matrix (ECM) proteins (e.g.
Bóta, Attila   +7 more
core   +1 more source

Perioperative hyperfibrinolysis – physiology and pathophysiology

open access: yesBrazilian Journal of Anesthesiology, 2021
Introduction and objectives: The role of the anesthesiologist in the perioperative management of hemostasis has attracted increasing attention. The fibrinolytic system participates in hemostasis, removing clots after repair of the vascular injury.
David Silveira Marinho
doaj  

Treatment of Bleeding Episodes With Efanesoctocog Alfa in Previously Treated Patients With Severe Hemophilia A in the Phase 3 XTEND‐1 Study

open access: yesAmerican Journal of Hematology, Volume 100, Issue 5, Page 813-820, May 2025.
ABSTRACT Despite therapeutic advances, people with hemophilia experience bleeds. These may be life‐threatening, result in permanent joint damage, chronic pain, difficulties with mobility/daily activities, and impact quality of life. In the XTEND‐1 study (NCT04161495), once‐weekly efanesoctocog alfa (50 IU/kg) prophylaxis provided highly effective bleed
Angela C. Weyand   +7 more
wiley   +1 more source

Uso tópico de agente antifibrinolítico na redução do sangramento após revascularização cirúrgica do miocárdio Topical use of antifibrinolytic agent to reduce postoperative bleeding after coronary artery bypass surgery

open access: yesBrazilian Journal of Cardiovascular Surgery, 2009
OBJETIVO: Verificar o efeito do uso tópico do ácido epsilon-aminocapróico (AEAC), aplicado na cavidade pericárdica, na redução do sangramento e necessidade de transfusão sanguínea no pós-operatório de revascularização cirúrgica do miocárdio.
João Roberto Breda   +7 more
doaj   +1 more source

Preventive and therapeutic effects of tranexamic acid on postpartum bleeding [PDF]

open access: yesReviews in Clinical Medicine, 2015
Postpartum hemorrhage is among the leading causes of maternal mortality throughout the world. Severe blood loss contributes to  the increased blood transfusion risk with its concerned inherent adverse events and therefore increased rate of emergency re ...
Samaneh Solltani   +3 more
doaj   +1 more source

Hermansky‐Pudlak Syndrome: From Molecular Pathogenesis to Targeted Therapies

open access: yesIUBMB Life, Volume 77, Issue 5, May 2025.
ABSTRACT Hermansky‐Pudlak syndrome (HPS) is a rare inherited disorder caused by defects in lysosome‐related organelles (LROs) in various tissues, including platelets, melanocytes, and endothelial cells. Key features of HPS include oculocutaneous albinism, bleeding tendency, and, in some cases, pulmonary fibrosis, granulomatous colitis, and ...
Francesca Tondi   +6 more
wiley   +1 more source

Re-Evaluation of the Role of Antifibrinolytic Therapy with Lysine Analogs in Liver Transplantation in The Post-Aprotinin Era [PDF]

open access: yes, 2012
Purpose of review: Hemorrhage, blood and blood product transfusions and the need for surgical re-exploration for bleeding can have a detrimental effect on patient outcome during liver surgery.
CONIGLIONE, FILADELFO   +9 more
core   +2 more sources

Approach to Hemoptysis in the Modern Era

open access: yesCanadian Respiratory Journal, 2017
Hemoptysis is a frequent manifestation of a wide variety of diseases, with mild to life-threatening presentations. The diagnostic workup and the management of severe hemoptysis are often challenging.
Sébastien Gagnon   +4 more
doaj   +1 more source

Fibrinolysis and bleeding of unknown cause

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2021
Patients with bleeding of unknown cause (BUC) present with a variety of mild to moderate bleeding symptoms, but no hemostatic abnormalities can be found. Hyperfibrinolysis is rarely evaluated as the underlying cause for bleeding in clinical practice, and
Dino Mehic   +3 more
doaj   +1 more source

On Networks with Active and Passive Agents [PDF]

open access: yesarXiv, 2014
We introduce an active-passive networked multiagent system framework, which consists of agents subject to exogenous inputs (active agents) and agents without any inputs (passive agents), and analyze its convergence using Lyapunov stability.
arxiv  

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