Results 71 to 80 of about 7,770 (215)

The usefulness of tranexamic acid for bleeding symptoms of chronic consumptive coagulopathy complicated by aortic disease: a single-institute, retrospective study of 14 patients

Thrombosis Journal, 2023
Background Tranexamic acid (TXA) is an antifibrinolytic drug that blocks lysine-binding sites on the profibrinolytic enzyme plasminogen. Aortic diseases with chronic consumption coagulopathy may lead to disseminated intravascular coagulation (DIC) and ...
Naruko Suzuki, Nobuaki Suzuki, Yuka Kawaguchi, Shuichi Okamoto, Takeshi Kanematsu, Akira Katsumi, Atsuo Suzuki, Shogo Tamura, Tetsuhito Kojima, Hitoshi Kiyoi, Tadashi Matsushita   +10 more
doaj   +1 more source

Declaring futility after traumatic injury and the burden of failure on the surgeon

Transfusion, Volume 66, Issue S1, Page S1-S4, May 2026.
Abstract In this edition of the THOR supplement in Transfusion, there are two articles that deal with resuscitation futility and transfusion. In one article, Yazer et al. delve into the details of the studies outlined in this editorial and summarize the literature on the topic of transfusion and futility. The second article by Dr.
Jan‐Michael Van Gent, Bryan A. Cotton
wiley   +1 more source

Effect of Prophylactic Intravenous Tranexamic Acid on Blood Loss After Vaginal Delivery: A Randomized Control Study

Health Science Reports
Background and Aim To determine the effect of prophylactic intravenous tranexamic acid on blood loss after vaginal delivery in women at low risk of postpartum hemorrhage.
Sajana Shrestha, Shelisha Uprety, Ravi Shah, Brinda Kharel   +3 more
doaj   +1 more source

Postoperative tonsil/adenoidectomy bleeding management in patients with diagnosed bleeding disorders

Laryngoscope Investigative Otolaryngology, 2021
Objective Tonsil/adenoidectomy (T/A) is a commonly performed procedure with an average post‐tonsillectomy bleed (PTB) rate between 3 and 5%. Patients with bleeding disorders (BDs) are believed to have an increased risk of PTB.
Kavya Pai, Harsh Desai, Dagmar Stein, Stephanie Cole   +3 more
doaj   +1 more source

Haematological and infectious complications associated with the treatment of patients with congenital cardiac disease: consensus definitions from the Multi-Societal Database Committee for Pediatric and Congenital Heart Disease [PDF]

, 2017
A complication is an event or occurrence that is associated with a disease or a healthcare intervention, is a departure from the desired course of events, and may cause, or be associated with, suboptimal outcome.
Bronicki, Ronald, Checchia, Paul A., Dodge-Khatami, Ali, Karamlou, Tara, Maruszewski, Bohdan, Ohye, Richard G.   +5 more
core  

Challenges in evaluating surgical innovation [PDF]

, 2009
Research on surgical interventions is associated with several methodological and practical challenges of which few, if any, apply only to surgery. However, surgical evaluation is especially demanding because many of these challenges coincide.
Blazeby, Jane M, Boutron, Isabelle, Clavein, Pierre-Alain, Cook, Jonathan Alistair, Ergina, Patrick L, Reeves, Barnaby C, Seiler, Christoph M   +6 more
core   +1 more source

Human α2‐Macroglobulin: Architecture, Mechanisms, and Functional Implications

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
Visual representation of human α2‐macroglobulin in its native and induced conformations. General functions associated with the native form (green), the induced form (white), and both conformations (light red) are indicated. ABSTRACT α2‐Macroglobulin (α2M) is a large glycoprotein and one of the most abundant proteins found in the plasma of vertebrates ...
Pietro de Carvalho Andrade, Tales Alexandre Costa‐Silva, Gisele Monteiro   +2 more
wiley   +1 more source

Influência do ácido épsilon aminocapróico no sangramento e na hemotransfusão pós-operatória em cirurgia valvar mitral Epsilon-aminocaproic acid influence in bleeding and hemotransfusion postoperative in mitral valve surgery

Brazilian Journal of Cardiovascular Surgery, 2010
INTRODUÇÃO: O ácido épsilon aminocapróico é um antifibrinolítico usado em cirurgia cardiovascular a fim de inibir a fibrinólise e reduzir o sangramento após circulação extracorpórea (CEC).
Ricardo Adala Benfatti, Amanda Ferreira Carli, Guilherme Viotto Rodrigues da Silva, Amaury Edgardo Mont'serrat Ávila Souza Dias, José Anderson Goldiano, José Carlos Dorsa Vieira Pontes   +5 more
doaj   +1 more source

An update on the management of anticoagulated patients programmed for dental extractions and surgery [PDF]

, 2008
Oral anticoagulants (OACs) antagonizing vitamin K - fundamentally sodium warfarin and acenocoumarol - are widely used for preventing arterial thromboembolism in patients with atrial fibrillation and/or heart valve prostheses, and for the treatment and ...
Gavaldá Esteve, Carmen, Jiménez Soriano, Yolanda, Margaix Muñoz, María, Poveda Roda, Rafael, Sarrión Pérez, María Gracia   +4 more
core  

Factor XIII Supplementation in Postpartum Hemorrhage: From Biological Rationale to Clinical Implementation

American Journal of Hematology, Volume 101, Issue 4, Page 794-806, April 2026.
ABSTRACT Postpartum hemorrhage (PPH) remains the leading cause of preventable maternal mortality despite standard interventions. Recent fibrinogen trials failed to improve outcomes, prompting interest in coagulation factor XIII (FXIII). FXIII functions as “molecular cement,” cross‐linking fibrin and stabilizing clots.
Jeremy W. Jacobs, Elizabeth A. Abels, Brian D. Adkins, Garrett S. Booth, Victoria Costa, Sheharyar Raza, Michelle Simon, Jennifer S. Woo, Allison P. Wheeler   +8 more
wiley   +1 more source