Results 51 to 60 of about 5,590 (131)

Effect of antifibrinolytic drugs on transfusion requirement and blood loss during orthotopic liver transplantation: Results from a single center

Asian Journal of Transfusion Science, 2008
Background: During orthotopic liver transplantation (OLT), activation of the fibrinolytic system can contribute significantly to perioperative bleeding.
Devi A, Kapoor Dharmesh, Gopal PBN, Subrahmanyam M, Ravichandra R   +4 more
doaj  

Topical vs. intravenous administration of tranexamic acid in knee arthroplasty and prevalence of deep venous thrombosis: a randomized clinical trial

Jornal Vascular Brasileiro
Background Tranexamic acid (TXA) is widely used in orthopedic surgery to reduce perioperative bleeding. Since TXA inhibits fibrinolysis, there is concern that it may increase the risk of thromboembolic events. Objectives To verify the prevalence of deep
Ari Zekcer, Ricardo Del Priori, Clauber Tieppo, Ricardo Soares da Silva, Nilson Roberto Severino   +4 more
doaj   +1 more source

Influência do ácido épsilon aminocapróico no sangramento e na hemotransfusão pós-operatória em cirurgia valvar mitral Epsilon-aminocaproic acid influence in bleeding and hemotransfusion postoperative in mitral valve surgery

Brazilian Journal of Cardiovascular Surgery, 2010
INTRODUÇÃO: O ácido épsilon aminocapróico é um antifibrinolítico usado em cirurgia cardiovascular a fim de inibir a fibrinólise e reduzir o sangramento após circulação extracorpórea (CEC).
Ricardo Adala Benfatti, Amanda Ferreira Carli, Guilherme Viotto Rodrigues da Silva, Amaury Edgardo Mont'serrat Ávila Souza Dias, José Anderson Goldiano, José Carlos Dorsa Vieira Pontes   +5 more
doaj   +1 more source

Role of defensins in immunothrombosis

Rheumatology &Autoimmunity, Volume 6, Issue 3, Page 138-148, September 2026.
Defensins are important proteins that link the immune system and blood clotting, playing a key role in immunothrombosis. α‐defensins mainly come from neutrophils, while β‐defensins are produced by epithelial cells and platelets. These proteins help form blood clots in several ways: they slow down clot breakdown (fibrinolysis), activate platelets, and ...
Yuebing Wang, Guijuan Guo, Xiangjun Liu, Xiaoyu Chen, Wenqiong Wang, Patapong Towiwat, Ru Li, Chun Li   +7 more
wiley   +1 more source

Advances in Skin Whitening Agents: Mechanisms, Clinical Applications, and Future Perspectives

Journal of Cosmetic Dermatology, Volume 25, Issue 9, September 2026.
ABSTRACT Background Skin hyperpigmentation disorders are common cosmetic and clinical concerns caused by excessive melanin production, abnormal pigment distribution, or persistent pigment after inflammation. Their heterogeneous pathogenesis and tendency to recur complicate treatment, particularly in patients with darker phototypes.
Yuanyuan Chen, Enhui Wang, Yize Li, Yanfang Yang, Zhaofeng Zhang, Junbo Wang, Yanfei Jiang, Chunyue Zhao   +7 more
wiley   +1 more source

A novel biosensor for measuring plasmin activity

Research and Practice in Thrombosis and Haemostasis
Background: Plasmin facilitates fibrinolysis by catalyzing the degradation of fibrin clots. Reliable methods to assess fibrinolysis by measuring plasmin generation are needed in the preclinical and clinical settings.
Ying Dai, Paul Y. Kim, Stefan Heitmeier, Jeffrey I. Weitz, Peter L. Gross   +4 more
doaj   +1 more source

Uso tópico de agente antifibrinolítico na redução do sangramento após revascularização cirúrgica do miocárdio Topical use of antifibrinolytic agent to reduce postoperative bleeding after coronary artery bypass surgery

Brazilian Journal of Cardiovascular Surgery, 2009
OBJETIVO: Verificar o efeito do uso tópico do ácido epsilon-aminocapróico (AEAC), aplicado na cavidade pericárdica, na redução do sangramento e necessidade de transfusão sanguínea no pós-operatório de revascularização cirúrgica do miocárdio.
João Roberto Breda, Danilo Bortoloto Gurian, Ana Silvia Castaldi Ragognetti Breda, Adriano Meneghine, Andréa Cristina de Oliveira Freitas, Leandro Mattos Luongo, Luiz Carlos de Abreu, Adilson Casemiro Pires   +7 more
doaj   +1 more source

Approach to Hemoptysis in the Modern Era

Canadian Respiratory Journal, 2017
Hemoptysis is a frequent manifestation of a wide variety of diseases, with mild to life-threatening presentations. The diagnostic workup and the management of severe hemoptysis are often challenging.
Sébastien Gagnon, Nicholas Quigley, Hervé Dutau, Antoine Delage, Marc Fortin   +4 more
doaj   +1 more source

Management of Antithrombotic Agents in Oral Surgery Maria Martinez and Dimitrios A. Tsakiris *

Dentistry Journal, 2015
Systemic anticoagulation with intravenous or oral anticoagulants and antiplatelet agents is an efficient treatment against thromboembolic or cardiovascular disease.
Maria Martinez, Dimitrios A. Tsakiris
doaj   +1 more source

Potent reduction of plasma lipoprotein (a) with an antisense oligonucleotide in human subjects does not affect ex vivo fibrinolysis

Journal of Lipid Research, 2019
It is postulated that lipoprotein (a) [Lp(a)] inhibits fibrinolysis, but this hypothesis has not been tested in humans due to the lack of specific Lp(a) lowering agents. Patients with elevated Lp(a) were randomized to antisense oligonucleotide [IONIS-APO(
Michael B. Boffa, Tanya T. Marar, Calvin Yeang, Nicholas J. Viney, Shuting Xia, Joseph L. Witztum, Marlys L. Koschinsky, Sotirios Tsimikas   +7 more
doaj   +1 more source