Results 41 to 50 of about 5,327 (168)

Prioritising parameters to minimise blood transfusions for postpartum haemorrhage: A machine learning study using national population data

Transfusion Medicine, EarlyView.
Abstract Background Postpartum haemorrhage (PPH) accounts for approximately 27% of maternal deaths worldwide and often requires blood transfusion, along with its associated risks. In resource‐rich settings like South Korea, transfusion disparities persist, highlighting the need for predictive tools to optimise patient blood management (PBM).
Ki Hoon Ahn, Yu‐Min Choi, Kwang‐Sig Lee   +2 more
wiley   +1 more source

Glanzmann thrombasthenia: genetic basis and clinical correlates

Haematologica, 2020
Glanzmann thrombasthenia (GT) is an autosomal recessive disorder of platelet aggregation caused by quantitative or qualitative defects in integrins αIIb and β3. These integrins are encoded by the ITGA2B and ITGB3 genes and form platelet glycoprotein (GP)
Juliana Perez Botero, Kristy Lee, Brian R Branchford, Paul F Bray, Kathleen Freson, Michele P. Lambert, Minjie Luo, Shruthi Mohan, Justyne E. Ross, Wolfgang Bergmeier, Jorge Di Paola   +10 more
doaj   +1 more source

Salts of S-(+)-Ibuprofen Formed via Its Reaction with the Antifibrinolytic Agents Aminocaproic Acid and Tranexamic Acid: Synthesis and Characterization

Crystals, 2023
The paucity of multi-component compounds containing the non-steroidal anti-inflammatory drug (NSAID) S-(+)-ibuprofen (S-IBU) in combination with other drugs prompted the present study, which describes 1:1 salts of this active pharmaceutical ingredient ...
Hannah M. Frösler, Humbelani S. Ramulumo, Cesarina Edmonds-Smith, Mino R. Caira   +3 more
doaj   +1 more source

Monitoring and feedback using data in transfusion medicine: A study of practices from the BEST Collaborative

Transfusion, EarlyView.
Abstract Background It is imperative that health systems monitor transfusion practice quality and implement improvements when evidence‐based practice gaps are identified. Despite the importance of data‐driven quality activities, little is known about approaches employed by hospitals. This study aimed to describe strategies used by hospitals to acquire,
Ryan A. Metcalf, Allison Mo, Sandra K. White, Gustavo C. Duarte, Nancy M. Dunbar, Katie Hands, Anil K. Panigrahi, Jessica L. Poisson, Nabiha H. Saifee, Hua Shan, Erica M. Wood, Michael F. Murphy, Simon J. Stanworth   +12 more
wiley   +1 more source

Substantial blood loss and transfusion burden after periacetabular osteotomy: Benchmark estimates from a systematic review and meta‐analysis

Knee Surgery, Sports Traumatology, Arthroscopy, Volume 34, Issue 7, Page 2576-2601, July 2026.
Abstract Purpose To establish pooled benchmark estimates for perioperative blood loss and transfusion burden after periacetabular osteotomy (PAO) and to explore potential study‐level moderators across the available literature. Methods A systematic search of PubMed, Embase, Epistemonikos and CENTRAL was performed up to 30 March 2026.
Nikolai Ramadanov, Jonathan Lettner, Roland Becker, Robert Prill, Marko Ostojic, Sufian S. Ahmad   +5 more
wiley   +1 more source

Severe Generalized Periodontitis in a Patient with an Aplastic Anemia: a 5 Year Follow-up Case Report

Acta Stomatologica Croatica, 2015
Aplastic anemia is a hematological disorder characterized by pancytopenia. This case report presents a young patient with untreated periodontitis associated with hematological disorders, and cyclosporine therapy.
Ivan Puhar, Darko Božić, Domagoj Žabarović, Damir Jelušić, Darije Plančak   +4 more
doaj   +1 more source

The usefulness of tranexamic acid for bleeding symptoms of chronic consumptive coagulopathy complicated by aortic disease: a single-institute, retrospective study of 14 patients

Thrombosis Journal, 2023
Background Tranexamic acid (TXA) is an antifibrinolytic drug that blocks lysine-binding sites on the profibrinolytic enzyme plasminogen. Aortic diseases with chronic consumption coagulopathy may lead to disseminated intravascular coagulation (DIC) and ...
Naruko Suzuki, Nobuaki Suzuki, Yuka Kawaguchi, Shuichi Okamoto, Takeshi Kanematsu, Akira Katsumi, Atsuo Suzuki, Shogo Tamura, Tetsuhito Kojima, Hitoshi Kiyoi, Tadashi Matsushita   +10 more
doaj   +1 more source

The role of antifibrinolytic agents in gynecologic cancer surgery

Saudi Medical Journal, 2006
OBJECTIVE: To compare the effects of crystalloid and colloid solutions, tranexamic acid and epsilon-aminocaproic acid on the need for allogenic blood transfusion and on coagulation and fibrinolysis parameters. METHODS: We conducted the study in the Anesthesiology and Reanimation Department of Hacettepe University Medical Faculty, Ankara, Turkey between
Nalan, Celebi, Bilge, Celebioglu, Mehtap, Selcuk, Ozgur, Canbay, Ayse H, Karagoz, Ulku, Aypar   +5 more
openaire   +2 more sources

Perioperative Management for Patients With Spinal Muscular Atrophy Undergoing Scoliosis Surgery: A Single‐Center Retrospective Study

Orthopaedic Surgery, Volume 18, Issue 7, Page 1328-1341, July 2026.
This largest Asian case series confirms that posterior spinal fusion for SMA scoliosis is safe and effective despite severe deformity and markedly impaired pulmonary function. Meticulous multidisciplinary care, including advanced airway planning, hemodynamic support, blood management, and proactive electrolyte correction, is critical to optimizing ...
Ai Hu, Xiuhua Zhang, Lulu Ma, Haisong Lu, Yulei Dong, Weiyun Chen, Yuguang Huang, Jianxiong Shen   +7 more
wiley   +1 more source

Postoperative tonsil/adenoidectomy bleeding management in patients with diagnosed bleeding disorders

Laryngoscope Investigative Otolaryngology, 2021
Objective Tonsil/adenoidectomy (T/A) is a commonly performed procedure with an average post‐tonsillectomy bleed (PTB) rate between 3 and 5%. Patients with bleeding disorders (BDs) are believed to have an increased risk of PTB.
Kavya Pai, Harsh Desai, Dagmar Stein, Stephanie Cole   +3 more
doaj   +1 more source