Results 41 to 50 of about 7,770 (215)

Inhibition of Fibrinolysis by Coagulation Factor XIII [PDF]

, 2017
The inhibitory effect of coagulation factor XIII (FXIII) on fibrinolysis has been studied for at least 50 years. Our insight into the underlying mechanisms has improved considerably, aided in particular by the discovery that activated FXIII cross-links ...
Rijken, D.C. (Dingeman), Uitte De Willige, S. (Shirley)   +1 more
core   +6 more sources

Antithrombotic therapy in patients receiving saphenous vein coronary artery bypass grafts: a protocol for a systematic review and network meta-analysis. [PDF]

, 2018
INTRODUCTION: The current evidence for the prevention of saphenous vein graft failure (SVGF) after coronary artery bypass graft (CABG) surgery consists of direct head-to-head comparison of treatments (including placebo) in randomised-controlled trials ...
Solo, K, Martin, J, Lavi, S, Kabali, C, John-Baptiste, A, Nevis, IF, Choudhury, T, Mamas, MA, Bagur, R   +8 more
core   +3 more sources

Acquired angioedema

Allergy, Asthma & Clinical Immunology, 2010
Acquired angioedema (AAE) is characterized by acquired deficiency of C1 inhibitor (C1-INH), hyperactivation of the classical pathway of human complement and angioedema symptoms mediated by bradykinin released by inappropriate activation of the contact ...
Cicardi Marco, Zanichelli Andrea
doaj   +1 more source

Hypofibrinolysis in diabetes: a therapeutic target for the reduction of cardiovascular risk [PDF]

, 2017
An enhanced thrombotic environment and premature atherosclerosis are key factors for the increased cardiovascular risk in diabetes. The occlusive vascular thrombus, formed secondary to interactions between platelets and coagulation proteins, is composed ...
A Agren, A Ceriello, A Hamsten, A Hamsten, A Lados-Krupa, A Liang, A Lutjens, A Rouch, A Rupin, A Sahebkar, A Tripodi, A Undas, A Undas, A Undas, AH Guimaraes, AH Henschen-Edman, AH Straten van, AS Wolberg, AS Wolberg, B Blomback, B Craen Van De, B Lipinski, B Rocca, B Wiman, B Zinman, BH Shieh, C Longstaff, CH Lundgren, CH Nair, CL Nikolajsen, CS Fox, D Capodanno, D Hill, D Leenaerts, D Ricklin, DA Gabriel, DA Lawrence, DA Lawrence, Darren Tomlinson, DJ Schneider, DL Crandall, DV Sakharov, E Angelantonio Di, E Chow, E Ernst, E Pretorius, E Pretorius, E Shacter, E Vercauteren, EG Levin, EJ Dunn, EJ Dunn, EL Hethershaw, EM Sherif, F Denorme, F Rollini, G Boden, G Gajos, G Jorneskog, GJ Brouwers, GK Hansson, GL Booth, GL Reed 3rd, GL Reed 3rd, H Elokdah, H Ritchie, HC Gerstein, HH Versteeg, HJ Beijers, HK Kim, I Juhan-Vague, I Shimomura, J Bester, J Danesh, J Montaner, J Svensson, J Weisel, JA Dormandy, JC Chapin, JD Mills, JG Dillinger, JH Foley, JL Ferreiro, JL Mega, JM Howes, JP Collet, JP Collet, JW Weisel, K Bangert, K Buelens, K Distelmaier, K Fatah, K Hess, K Hess, K Hess, K Leander, K Leander, Katherine Kearney, KE Brummel, Kerrie Smith, KN Lee, KN Lee, KN Lee, KN Lee, KN Lee, KR Machlus, L Badimon, L Ryden, L Wallentin, LM Belalcazar, M Konieczynska, M Pieters, M Pieters, M Pieters, M Rigla, M Udvardy, MA Bailey, MB Kahn, MC Alessi, ME Carr Jr, ME Meltzer, ME Meltzer, ME Meltzer, ME Stegenga, MG Marini, MR Hammer, MS Ardawi, N Gogitidze Joy, N Zheng, NH Tilburg van, NV Gorlatova, O Sigurdardottir, OJ Phung, P Chudy, P Clemmensen, P Katz, P Kohli, P Soma, P Soma, R Ajjan, R Favier, R King, RA Ajjan, RA Ajjan, RA Al-Horani, Ramzi Ajjan, RM Cubbon, RM Missov, RP Rother, RR Holman, S James, S Kimura, S Kimura, S Neergaard-Petersen, S Schulman, S Tehrani, S Tehrani, S Yener, SD Wiviott, SD Wiviott, SH Alzahrani, SH Alzahrani, SJ Cleland, SK Kunutsor, SL Carpenter, SP Marso, SR Fraser, ST Lord, T Koyama, T Kumada, T Lisman, T Plug, T Sasaki, T Tamaki, T Wyseure, T Wyseure, TC Holten van, TW Meade, U Amara, V Baeriswyl, VR Richardson, WB Kannel, X Zhou, X Zhou, Y Hori, Y Sakata, Y Sakata, Y Sakata, Y Sumi, Y Yano, YM Fortenberry, Z Valnickova   +191 more
core   +2 more sources

Porcine kidney xenotransplantation: From primate models to clinical reality

Animal Models and Experimental Medicine, EarlyView.
In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo, Ling Zhang, Shoulong Deng, Chuan Qin   +3 more
wiley   +1 more source

Tranexamic Acid in Lower Extremity Endoprosthetic Reconstruction for Oncologic Indications: A Retrospective Comparative Study of 617 Patients

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives While tranexamic acid (TXA) reduces blood loss in orthopedic surgery, thromboembolic concerns in cancer patients have limited adoption in orthopedic oncology. This study evaluated TXA efficacy and safety in patients undergoing endoprosthetic reconstruction for oncologic indications.
Stephen W. Chenard, Akhil Rekulapelli, Riley S. Gilbertson, Connor S. Charton, William F. Hefley, Michael J. Colello, Jennifer L. Halpern, Herbert S. Schwartz, Daniel J. Johnson, Jonathan G. Schoenecker, Joshua M. Lawrenz   +10 more
wiley   +1 more source

Tranexamic acid dosing strategies and blood loss reduction in multilevel spine surgery: A systematic review and network meta-analysis

North American Spine Society Journal, 2021
Background: For adults undergoing complex, multilevel spinal surgery, tranexamic acid (TXA) is an antifibrinolytic agent used to reduce blood loss. The optimal dosing of intravenous TXA remains unclear.
Roman Rahmani, Amy Singleton, Zachary Fulton, John M. Pederson, Thomas Andreshak   +4 more
doaj   +1 more source

Kaposiform hemangioendothelioma: Diagnosis and treatment

Pediatric Investigation, EarlyView.
Vascular endothelial growth factor‐C (VEGF‐C)/vascular endothelial growth factor receptor‐3 (VEGFR‐3) and angiopoietin‐2 (Ang‐2)/tyrosine kinase with immunoglobulin‐like and EGF‐like domain 2 (TIE2) signaling pathways play an important role in lymphangiogenesis.
Yi Tian, Yuanyuan Tian, Li Wei, Zigang Xu, Li Li, Lin Ma   +5 more
wiley   +1 more source

The use of fibrinolysis inhibitors in cardiac surgery with cardiopulmonary bypass (literature review)

Вестник анестезиологии и реаниматологии
In cardiac surgery with cardiopulmonary bypass (CPB) is a common complication. The incidence of this complication in cardiac surgery patients is estimated at about 10%.
V. Yu. Medvedeva, K. N. Khrapov, A. A. Khryapa, K. Yu. Kankova   +3 more
doaj   +1 more source

Antifibrinolytics in cardiac surgery

Annals of Cardiac Anaesthesia, 2013
Cardiac surgery exerts a significant strain on the blood bank services and is a model example in which a multi-modal blood-conservation strategy is recommended.
Achal Dhir
doaj   +1 more source