Results 21 to 30 of about 5,327 (168)
Anti-fibrinolytic agents in post partum haemorrhage: a systematic review
BMC Pregnancy and Childbirth, 2009 Background Post partum haemorrhage is a leading cause of maternal death worldwide. It also contributes to maternal morbidity as women may require a hysterectomy to control bleeding, or may require a blood transfusion, which can transmit viral infections.
Blackhall Karen +4 more
doaj +1 more source
Perioperative hyperfibrinolysis – physiology and pathophysiology
Brazilian Journal of Anesthesiology, 2021 Introduction and objectives: The role of the anesthesiologist in the perioperative management of hemostasis has attracted increasing attention. The fibrinolytic system participates in hemostasis, removing clots after repair of the vascular injury.
David Silveira Marinho
doaj +1 more source
COMPARISON OF HEMOSTASIS WITH TRANEXAMIC ACID IN TOTAL KNEE ARTHROPLASTY
Acta Ortopédica Brasileira, 2021 Objective: To compare the use of intravenous and topical tranexamic acid (TXA) in unilateral primary total knee arthroplasty (TKA) in relation to blood loss and complications inherent to the medication.
OTÁVIO MONTOVANELLI MONTEIRO +5 more
doaj +1 more source
Health Technology Assessment, 2021 Background: Tranexamic acid safely reduces mortality in traumatic extracranial bleeding. Intracranial bleeding is common after traumatic brain injury and can cause brain herniation and death.
Ian Roberts +19 more
doaj +1 more source
Plasmin Inhibitor in Health and Diabetes: Role of the Protein as a Therapeutic Target
TH Open, 2022 The vascular obstructive thrombus is composed of a mesh of fibrin fibers with blood cells trapped in these networks. Enhanced fibrin clot formation and/or suppression of fibrinolysis are associated with an increased risk of vascular occlusive events ...
Basmah Alsayejh +6 more
doaj +1 more source
Minimal Dose of Tranexamic Acid Is Effective in Reducing Blood Loss in Complex Spine Surgeries: A Randomized Double-Blind Placebo Controlled Study [PDF]
Asian Spine Journal, 2018 Study Design A randomized double-blind placebo controlled study. Purpose In the present study, we aimed to assess the efficacy of tranexamic acid (TXA) in reducing blood loss after laminectomy and posterolateral fusion of the spine.
Moslem Shakeri +6 more
doaj +1 more source
Frontiers in Medicine, 2019 Extracorporeal membrane oxygenation (ECMO) is a life-saving procedure that requires careful coagulation management. Indications for ECMO continue to expand, leading to more complicated patients treated by ECMO teams.
Lisa A. Hensch +5 more
doaj +1 more source
Porcine kidney xenotransplantation: From primate models to clinical reality
Animal Models and Experimental Medicine, EarlyView.In the face of a critical shortage of human donor kidneys for end‐stage renal disease patients, porcine kidney xenotransplantation has emerged as a viable solution. This field has navigated major hurdles, including immune rejection, physiological incompatibilities, potential biomechanical differences and the risk of cross‐species infection. To overcome
Zihang Guo +3 more
wiley +1 more source
Evolving perspectives on blood transfusion in obstetric hemorrhage: a narrative review [PDF]
Korean Journal of AnesthesiologyGlobally, postpartum hemorrhage is still among the most significant factors in preventable maternal morbidity and mortality. Although early recognition and intervention have improved with advances in obstetric care, transfusion practices are often based ...
Yoon Ji Choi, Sang Hun Kim
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Allergy, EarlyView.ABSTRACT Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disease characterized by unpredictable episodes of tissue swelling (angioedema), which, in most cases, occur first under the age of 18 years, and entail a significant burden of disease not only for the patients but also for their families.
Henriette Farkas +128 more
wiley +1 more source