Efficacy and Safety of Antifibrinolytic Agents in Reducing Perioperative Blood Loss and Transfusion Requirements in Scoliosis Surgery: A Systematic Review and Meta-Analysis. [PDF]
PLoS ONE, 2015 BackgroundRoutine use of antifibrinolytic agents in spine surgery is still an issue of debate.ObjectiveTo gather scientific evidence for the efficacy and safety of antifibrinolytic agents including aprotinin, tranexamic acid (TXA) and epsilon ...
Meng Wang +2 more
doaj +4 more sources
Efficacy and safety of using antifibrinolytic agents in spine surgery: a meta-analysis. [PDF]
PLoS ONE, 2013 PURPOSE: Spine surgery, particularly reconstructive surgery, can be associated with significant blood loss, and blood transfusion. Antifibrinolytic agents are used routinely to reduce bleeding in cardiac, orthopaedic, and hepatic surgery.
Chaoqun Yuan, Hailong Zhang, Shisheng He
doaj +2 more sources
Efficacy and safety of antifibrinolytic agents in spinal surgery: a network meta-analysis [PDF]
Chinese Medical Journal, 2019 . Background:. Significant blood loss is still one of the most frequent complications in spinal surgery, which often necessitates blood transfusion. Massive perioperative blood loss and blood transfusion can create additional risks. Aprotinin, tranexamic
Lei Yuan +7 more
doaj +2 more sources
Effectiveness and safety of antifibrinolytic agents in off-pump coronary artery bypass grafting: a systematic review and meta-analysis [PDF]
Brazilian Journal of AnesthesiologyBackground: Coronary Artery Bypass Grafting (CABG) is the most widely used cardiac intervention and can be accomplished without an extracorporeal circulation off-pump.
João Lucas W.C. Marchesani +5 more
doaj +2 more sources
Antifibrinolytic Agents for Reducing Blood Loss in Scoliosis Surgery in Children [PDF]
Cochrane Database of Systematic Reviews, 2016 Roman Schumann +2 more
exaly +2 more sources
Tranexamic Acid; A Glittering Player in the Field of Trauma [PDF]
Bulletin of Emergency and Trauma, 2020 Trauma is still the leading cause of mortality and morbidity worldwide with an estimated 5.8 million mortalities every year [1] and approximately 60 million traumatic brain injuries (TBI) annually [2]. Hemorrhage remains the most common preventable cause
Fariborz Ghaffarpasand +4 more
doaj +1 more source
Antifibrinolytic agents for the prevention of postpartum hemorrhage
Thrombosis Update, 2021 Acute obstetric coagulopathy secondary to postpartum hemorrhage (PPH) is associated with poor outcome. There is evidence that Tranexamic Acid (TA), an antifibrinolytic drug, is an efficient tool of patient blood management in association with uterotonics
Anne-Sophie Bouthors +3 more
doaj +1 more source
Postoperative Low-Dose Tranexamic Acid After Major Spine Surgery: A Matched Cohort Analysis [PDF]
Neurospine, 2020 Objective This was a retrospective, cohort study investigating the efficacy and safety of continuous low-dose postoperative tranexamic acid (PTXA) on drain output and transfusion requirements following adult spinal deformity surgery.
Lauren K. Dunn +13 more
doaj +1 more source
Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal
Periodontology 2000, EarlyView., 2023 Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra +3 more
wiley +1 more source
The Effect of Tranexamic Acid (Cyclokapron) on Post–Surgical Bleeding Following the Removal of Impacted Lower Wisdom Teeth in Healthy Individuals [PDF]
Al-Rafidain Dental Journal, 2008 Aims: To evaluate the effect of local irrigation with tranexamic acid in minimizing post–operative bleeding following the removal of impacted lower wisdom teeth.
Rayan S. Hamid +2 more
doaj +1 more source