Antifibrinolytics in liver surgery
Indian Journal of Anaesthesia, 2010 Hyperfibrinolysis, a known complication of liver surgery and orthotopic liver transplantation (OLT), plays a significant role in blood loss. This fact justifies the use of antifibrinolytic drugs during these procedures.
Jalpa Makwana +2 more
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Using antifibrinolytics to tackle neuroinflammation [PDF]
Neural Regeneration Research, 2020 Plasmin is generally known as a promotor of inflammation. Recent advancement suggests that it has a complex role as immunity modulator. Pharmacological inhibition of plasmin production and activity has been proven to improve neurological outcomes in ...
Stanimir Atsev, Nikola Tomov
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No Difference Between Blood Preserving Strategies During Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis [PDF]
Journal of the Pediatric Orthopaedic Society of North AmericaBackground: There is conflicting evidence on whether normovolemic hemodilution is efficacious in reducing intraoperative blood loss and transfusions, and existing pediatric literature does not evaluate hemodilution in combination with antifibrinolytics ...
Akshitha Adhiyaman, MD +3 more
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Antifibrinolytics in cardiac surgery
Annals of Cardiac Anaesthesia, 2013 Cardiac surgery exerts a significant strain on the blood bank services and is a model example in which a multi-modal blood-conservation strategy is recommended.
Achal Dhir
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Future Science OA, 2023 Aim: The efficacy of antifibrinolytics in subarachnoid hemorrhage remains unclear due to conflicting evidence from studies. Materials & methods: Online databases were queried to include randomized controlled trials and propensity matched observational ...
Kaneez Fatima +11 more
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Benefits of Antifibrinolytics in Minimally Invasive Surgical Repair of Single-suture Craniosynostosis [PDF]
Plastic and Reconstructive Surgery, Global OpenBackground:. The utility of antifibrinolytics in minimally invasive craniosynostosis repair lacks established consensus. This study aimed to assess the impact of antifibrinolytic administration on intraoperative blood loss; length of hospital stay ...
Gabrielle C. Rodriguez, MD +7 more
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Not so benign: Life-threatening hematuria from renal papillary necrosis in sickle cell trait [PDF]
Urology Case ReportsRenal papillary necrosis (RPN) is an uncommon but important cause of hematuria in patients with sickle cell trait. We report a 28-year-old female with sickle cell trait and beta thalassemia who developed recurrent, transfusion-dependent gross hematuria ...
Katharine Hodgen +3 more
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Acute Hemorrhagic Manifestations in a Pregnant Patient With Type 1 von Willebrand Disease: Challenges in Management of Bleeding Disorders During Gestation [PDF]
Clinical Case ReportsThis case reports a primigravida with Type 1 von Willebrand disease experiencing hematuria and gingival bleeding despite prophylaxis. Although pregnancy raises factor levels, her response was insufficient.
Jose Luis Rojas‐Oviedo +5 more
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Effectiveness and safety of antifibrinolytic agents in off-pump coronary artery bypass grafting: a systematic review and meta-analysis [PDF]
Brazilian Journal of AnesthesiologyBackground: Coronary Artery Bypass Grafting (CABG) is the most widely used cardiac intervention and can be accomplished without an extracorporeal circulation off-pump.
João Lucas W.C. Marchesani +5 more
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Tranexamic Acid; A Glittering Player in the Field of Trauma [PDF]
Bulletin of Emergency and Trauma, 2020 Trauma is still the leading cause of mortality and morbidity worldwide with an estimated 5.8 million mortalities every year [1] and approximately 60 million traumatic brain injuries (TBI) annually [2]. Hemorrhage remains the most common preventable cause
Fariborz Ghaffarpasand +4 more
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