The international, prospective Glanzmann Thrombasthenia Registry: treatment and outcomes in surgical intervention [PDF]
Standard treatment for Glanzmann thrombasthenia, a severe inherited bleeding disorder, is platelet transfusion. Recombinant factor VIIa is reported to be effective in Glanzmann thrombasthenia with platelet antibodies and/or refractoriness to platelet ...
Man-Chiu Poon +5 more
doaj +2 more sources
The international, prospective Glanzmann Thrombasthenia Registry: treatment modalities and outcomes of non-surgical bleeding episodes in patients with Glanzmann thrombasthenia [PDF]
Standard treatment for Glanzmann thrombasthenia is platelet transfusion. Recombinant activated factor VII has been shown to be successful in patients with Glanzmann thrombasthenia with platelet antibodies or who are refractory to platelet transfusions ...
Giovanni Di Minno +5 more
doaj +2 more sources
Case of the successful outcome of obstetrical haemorrhage with the syndrome intravascular curtailing of blood of the 3-rd stage [PDF]
The article describes the case of successful outcome of the patient after the haemorrhage, that move than 50% of volume of circulating blood, conditions of the patient was complicated by the development of the 3-rd stage of syndrome intravascular ...
A. N. Rymashevsky +2 more
doaj +1 more source
Pathogenetically justified tactics of management of pregnancy with retrochorial hematoma
Introduction. Retrochorial hematoma (RH) often detected during routine ultrasound examination represents one of the multiple causes resulting in early pregnancy loss. RH results from the detachment of the chorionic plate from the vertebrae of the uterine
K. G. Sultangadzhieva +4 more
doaj +1 more source
Periodontitis and atherosclerotic cardiovascular disease: A critical appraisal
Abstract In spite of intensive research efforts driving spectacular advances in terms of prevention and treatments, cardiovascular diseases (CVDs) remain a leading health burden, accounting for 32% of all deaths (World Health Organization. “Cardiovascular Diseases (CVDs).” WHO, February 1, 2017, https://www.who.int/news‐room/fact‐sheets/detail ...
Maria Clotilde Carra +3 more
wiley +1 more source
Background: Intraoperative bleeding and allogeneic transfusion remain common problems in pediatric resective epilepsy surgery. Tranexamic acid (TXA) is a widely recommended antifibrinolytic drug that reduces blood loss and transfusion requirements for ...
Ting Zhang +11 more
doaj +1 more source
The paucity of multi-component compounds containing the non-steroidal anti-inflammatory drug (NSAID) S-(+)-ibuprofen (S-IBU) in combination with other drugs prompted the present study, which describes 1:1 salts of this active pharmaceutical ingredient ...
Hannah M. Frösler +3 more
doaj +1 more source
Patients with Antiphospholipid syndrome (APLS) are at high risk for both bleeding and thrombotic complications during cardiac surgery involving cardiopulmonary bypass (CPB).
Sanjana A Malviya +5 more
doaj +1 more source
Use of tranexamic acid in dogs with primary immune thrombocytopenia: A feasibility study
ObjectiveThe aim of this feasibility study is to evaluate the use of tranexamic acid and its safe use alongside standard therapy in dogs with primary immune thrombocytopenia (ITP).DesignThis is a cohort feasibility study involving 10 dogs diagnosed with ...
Gerard Olivares +5 more
doaj +1 more source
Efficacy and safety of antifibrinolytics in oncological surgery: a systematic review and meta-analysis [PDF]
Background and objectives: The administration of antifibrinolytics has been shown to be effective in reducing blood loss and the need for transfusions in surgeries. However, few studies have evaluated these drugs in cancer surgery.
Aline Menezes Sampaio +7 more
doaj +5 more sources

