Results 41 to 50 of about 3,193 (201)

A Rare Case of Acquired Haemophilia A Following Sigmoid Adenocarcinoma: Case Report and Literature Review

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Acquired haemophilia A (AHA) is a rare complication of malignancy. We report a case of AHA secondary to colorectal cancer which presented as post‐operative bleeding, progressive activated partial thromboplastin time prolongation, precipitous factor VIII (FVIII) decline and inhibitor development.
Benjamin Reardon, Harini Haran, Jennifer Curnow   +2 more
wiley   +1 more source

A survey of patient blood management for patients undergoing cardiac surgery in nine European countries [PDF]

, 2021
Study objective: To describe and compare patient blood management (PBM) practices in cardiac surgery in nine European countries and identify the main risk factors for bleeding or transfusion according to the surveyed centres. Design: We set up an online
Andrew Klein, Paulus, Patrick, Steffen Rex, Agarwal, Seema, Michael Griffin, Timo Kaakinen, van Saet, Annewil, Kaakinen, Timo, Patrick Paulus, Klein, Andrew, Cholley, Bernard, Rex, Steffen, Jens Fassl, Seema Agarwal, A. (Annewil) van Saet, Griffin, Michael, Mzallassi, Zineb, Z. (Zineb) Mzallassi, Bernard Cholley, Martin Siegemund, Fassl, Jens, Siegemund, Martin, Annewil van Saet, Zineb Mzallassi   +23 more
core   +1 more source

Medical treatment for heavy menstrual bleeding

Taiwanese Journal of Obstetrics & Gynecology, 2015
Heavy menstrual bleeding, or menorrhagia, is subjectively defined as a “complaint of a large amount of bleeding during menstrual cycles that occurs over several consecutive cycles” and is objectively defined as menstrual blood loss of more than 80 mL per
Yi-Jen Chen, Yiu-Tai Li, Ben-Shian Huang, Ming-Shyen Yen, Bor-Ching Sheu, Song-Nan Chow, Peng-Hui Wang   +6 more
doaj   +1 more source

Topical Tranexamic Acid in Breast Surgery: A Systematic Review and Meta‐Analysis of Postoperative Bleeding Outcomes

ANZ Journal of Surgery, EarlyView.
Study evaluated the effectiveness and safety of topical tranexamic acid in breast surgery. Topical TXA reduced postoperative haematoma risk by 75% and significantly decreased postoperative drain output compared with controls, while seroma rates were unchanged.
Sina Sobhanmanesh, Femi E. Ayeni, Deborah S. M. Cheung   +2 more
wiley   +1 more source

A review of European guidelines for patient blood management with a particular emphasis on antifibrinolytic drug administration for cardiac surgery [PDF]

, 2022
The concept of patient blood management (PBM) was introduced by the World Health Organization in 2011 and is defined as a "patient-focused, evidence-based and systematic approach for optimizing the management of patients and transfusion of blood products
Griffin, Michael, Paulus, Patrick, Agarwal, Seema, van Saet, Annewil, Kaakinen, Timo, Klein, Andrew, Cholley, Bernard, Rex, Steffen, Fassl, Jens, Siegemund, Martin, Andrew Klein, Annewil van Saet, Steffen Rex, Michael Griffin, Timo Kaakinen, Patrick Paulus, Bernard Cholley, Jens Fassl, Martin Siegemund, Seema Agarwal   +19 more
core   +1 more source

Do antifibrinolytics reduce allogeneic blood transfusion in orthopedic surgery?

, 2006
International audienceStudies have shown that antifibrinolytic (aprotinin, tranexamic acid, epsilon-aminocaproic acid) reduce blood loss in orthopedic surgery. However, most lacked sufficient power to evaluate the efficacy and safety on clinical outcomes.
Mismetti, Patrick, Zufferey, Paul, Merquiol, Fanette, Decousus, Hervé, Auboyer, Christian, Samama, Charles Marc, Laporte, Silvy, Molliex, Serge   +7 more
core   +2 more sources

The effect of ε‐aminocaproic acid on blood product requirement, outcome and thromboelastography parameters in severely thrombocytopenic dogs

Journal of Veterinary Internal Medicine
Background No treatment other than platelet administration is known to protect against spontaneous hemorrhage in thrombocytopenic dogs. Objectives Primary: determine if treatment with ε‐aminocaproic acid (EACA) decreases the requirement for blood ...
Johanna Wolf, Laura K. Ruterbories, Ian Handel, Bernie Hansen   +3 more
doaj   +1 more source

The effectiveness and safety of antifibrinolytics in patients with acute intracranial haemorrhage: statistical analysis plan for an individual patient data meta-analysis [version 1; referees: 2 approved]

Wellcome Open Research, 2017
Introduction: The Antifibrinolytic Trialists Collaboration aims to increase knowledge about the effectiveness and safety of antifibrinolytic treatment by conducting individual patient data (IPD) meta-analyses of randomised trials.
Katharine Ker, David Prieto-Merino, Nikola Sprigg, Abda Mahmood, Philip Bath, Zhe Kang Law, Katie Flaherty, Ian Roberts   +7 more
doaj   +1 more source

Enhancing the Evidence for Care in Underserved Bleeding Disorders Communities

Haemophilia, EarlyView.
ABSTRACT Background Major advances in haemophilia care have not translated equitably across all populations. Individuals with rare bleeding disorders (RBDs), people living in low‐ and lower‐middle‐income countries (LMICs) and women and girls with inherited bleeding disorders (WGWBD) continue to face significant diagnostic, therapeutic and research ...
Johnny Mahlangu
wiley   +1 more source

RARE PLATELET DISORDER GLANZMANN THROMBASTHENIA CAUSING ABNORMAL UTERINE BLEEDING A CASE REPORT AND REVIEW OF LITERATURE

, 2022
Glanzmann thrombasthenia is a rare genetic disorder. It is of autosomal inheritance. It usually presents as ecchymoses, petechiae, gum bleeding, musical bleeding, and menorrhagia.
Abhay Kumar and Subash Chander Saha
core   +1 more source