Results 61 to 70 of about 3,193 (201)
Introducción: la enfermedad de Von Willebrand es el trastorno de la coagulación con mayor prevalencia de mujeres en edad fértil y, por lo tanto, es el trastorno genético de la hemostasia más frecuente en la práctica ginecológica y obstétrica.
Franklin J Espitia-De La Hoz
doaj
ABSTRACT Background Direct oral anticoagulants (DOACs) are the first‐line therapy for stroke prevention in non‐valvular atrial fibrillation and venous thromboembolism. While evidence supports their continuation during routine dental procedures such as tooth extractions, data on oral soft tissue biopsies remain limited.
Rossana Izzetti +3 more
wiley +1 more source
Antifibrinolytics in a rural trauma state: assessing the opportunities
Background Tranexamic acid (TXA) has demonstrated improved mortality among trauma patients. However, recent evidence from urban US trauma centers has failed to show a benefit among the civilian population. TXA in rural states has not been evaluated. This
Alison Wilson +4 more
doaj +1 more source
Abstract Background Postpartum haemorrhage (PPH) accounts for approximately 27% of maternal deaths worldwide and often requires blood transfusion, along with its associated risks. In resource‐rich settings like South Korea, transfusion disparities persist, highlighting the need for predictive tools to optimise patient blood management (PBM).
Ki Hoon Ahn +2 more
wiley +1 more source
Abstract Objectives To highlight tranexamic acid (TXA) as ‘just one thing’ that every hospital could implement to reduce surgical bleeding and blood transfusions. Background TXA is a low‐cost antifibrinolytic agent that inhibits the breakdown of fibrin blood clots. Developed in Japan in the 1960s, it has been shown to reduce surgical bleeding.
Ian Roberts, Katharine Ker
wiley +1 more source
Alternativas farmacológicas a la transfusión sanguínea: ¿Qué hay de nuevo? [PDF]
Pharmacological approaches to reduce blood transfusion include the protease inhibitor aprotinin, lysine-analogue antifibrinolytics synthetic arginine-vasopressin derivatives (DDAVP) and recombinant factor VII (rfVIIa).
Milagros Hernández +7 more
core +1 more source
Abstract Background Perioperative autologous transfusion, encompassing intraoperative cell salvage (ICS), acute normovolemic hemodilution (ANH), and autologous component production, is integral to patient blood management. Association for the Advancement of Blood and Biotherapies (AABB) has published comprehensive quality standards, yet perioperative ...
Gagan Mathur +7 more
wiley +1 more source
Background Hemoptysis is a potentially life-threatening condition with variable etiology and severity. Tranexamic acid (TXA), an antifibrinolytic agent, has demonstrated efficacy in bleeding control.
Eman A.A. Ali +2 more
doaj +1 more source
Inter‐institutional perspectives on usage of fibrinogen replacement therapies in North America
Abstract Background and Objectives Cryoprecipitated antihemophilic factor (cryoprecipitate), fibrinogen concentrate (FC), and pathogen‐reduced cryoprecipitated fibrinogen complex (PR cryoprecipitate) are sources of fibrinogen replacement, and each has advantages and disadvantages in terms of cost, efficacy, safety, and logistics of administration. This
Cindy Tay +5 more
wiley +1 more source
Neutrophil Extracellular Traps Block Fibrinolysis in Ischemic Stroke
Objectives Intravenous thrombolysis (IVT) failure in acute ischemic stroke (AIS) is frequent, but its causes remain elusive. We investigated whether biologically relevant intrathrombus concentrations of tissue plasminogen activator (tPA) were achieved in failed IVT and whether neutrophil extracellular traps (NETs) contributed to this therapeutic ...
Mialitiana Solo Nomenjanahary +21 more
wiley +1 more source

