Results 51 to 60 of about 3,193 (201)

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

Haemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini, Robert Klamroth, Bauke Haisma, Dino Mehic, Saskia E. M. Schols   +4 more
wiley   +1 more source

The relative efficacy of antifibrinolytics in adolescent idiopathic scoliosis: a prospective randomized trial. [PDF]

, 2014
BACKGROUND: Antifibrinolytics can reduce intraoperative blood loss. The primary aim of this study was to determine the efficacy of intraoperative tranexamic acid, epsilon-aminocaproic acid, and placebo at reducing perioperative blood loss and the ...
Lonner, Baron S, Errico, Thomas, Dryer, Joseph, Huncke, Tessa, Verma, MD, Kushagra, Diefenbach, Chris, Boenigk, Kirstin, Hoelscher, Christian, Peters, Austin   +8 more
core   +1 more source

Tranexamic versus aminocaproic acids in patients with total hip arthroplasty: a retrospective study

BMC Musculoskeletal Disorders, 2022
Background Recently, tranexamic acid (TXA) and epsilon aminocaproic acid (EACA) have been applied in total hip arthroplasty (THA). However, doubts in clinicians’ minds about which medicine is more efficient and economical in THA need to be clarified ...
Hui Xie, Yu-Shen Yang, Si-miao Tian, Ben-jie Wang, Wei-min Fu, Liang-liang Cheng, Nan-nan Jiang, Guishan Gu, De-wei Zhao   +8 more
doaj   +1 more source

Symptoms, Diagnosis, and Treatment for Women and Girls With Hemophilia: A Narrative Review

Haemophilia, EarlyView.
ABSTRACT Introduction Hemophilia is an X‐linked bleeding disorder previously thought to present only in men. This sentiment is rapidly changing as the information around women and girls’ experiences of bleeding symptoms has evolved, sparking intense discussion among researchers, clinicians, patients, and patient advocates regarding appropriate ...
Sam Hirniak, Carla Samuel, Faria Aditi, Haya Abu Ghazaleh, Dawn Rotellini, Menaka Pai, Andrea Edginton   +6 more
wiley   +1 more source

Risk of Postpartum Hemorrhage in Women With Von Willebrand Disease: A Real‐World Data Analysis

Haemophilia, EarlyView.
ABSTRACT Introduction Women with von Willebrand disease (VWD) are at increased risk for postpartum hemorrhage (PPH), but contemporary United States data on maternal outcomes and real‐world peripartum treatment patterns are limited. Aim To evaluate maternal outcomes associated with claims‐recorded VWD in a national claims cohort and describe exploratory
Mayank Patel, Victor Zibara, Craig Seaman, Sruti Shiva, Nicoletta C. Machin   +4 more
wiley   +1 more source

Role of prophylactic tranexamic acid in reducing blood loss during cesarean section: A double-blind placebo-controlled randomized controlled trial

Journal of Family Medicine and Primary Care
Background: Postpartum hemorrhage (PPH) is defined by the World Health Organization as blood loss of ≥500 mL within 24 h of delivery. Globally, hemorrhage accounts for 27.1% of maternal deaths, making it the leading direct cause of maternal death.
Nutan Sinha, Sarita Rajbhar, Pushpawati Thakur, Sarita Agrawal, Vinita Singh   +4 more
doaj   +1 more source

Antioxidant Activity and Potential Bioactive Peptides from Skin Protein Hydrolysate of Yellowfin Tuna (Thunnus albacares)

Jurnal Ilmiah Perikanan dan Kelautan, 2023
Highlight Research • Immersion of tuna skin using NaHCO3 at low temperatures effectively reduces the fat content. • The DH value, MW, and amino acid composition are in line with the antioxidant activity of tuna skin hydrolysate.
Sitti Hardiyanti Rachman, Joko Santoso, Sugeng Heri Suseno   +2 more
doaj   +1 more source

Perioperative Management in Persons With Haemophilia on Rebalancing Therapies: A Narrative Review

Haemophilia, EarlyView.
ABSTRACT Introduction Perioperative management in haemophilia often requires on‐demand use of clotting factor concentrates (CFC) and/or bypassing agents. Rebalancing agents (fitusiran, concizumab, marstacimab) offer a novel approach to prophylaxis by modulating endogenous anticoagulant pathways to restore haemostatic balance.
Amanda M. Henderson, Roy Khalife, Kelsey Uminski   +2 more
wiley   +1 more source

Antifibrinolytics and cardiac surgery: The past, the present, and the future

Annals of Cardiac Anaesthesia, 2020
Cardiac surgery is usually associated with significant blood loss, which often necessitates blood transfusion. In order to decrease the risks associated with the latter, pharmacological as well as nonpharmacological strategies have been used to reduce ...
Naresh K Aggarwal, Arun Subramanian
doaj   +1 more source

Diagnostic and Treatment Availability of von Willebrand Disease Within Europe: Insights From a European Association for Hemophilia and Allied Disorders (EAHAD) Survey

Haemophilia, EarlyView.
ABSTRACT Background Von Willebrand disease (VWD) is the most common inherited bleeding disorder, yet its diagnosis and management remain heterogeneous across Europe due to variable access to diagnosis and care. Aim To characterize diagnostic and treatment practices for VWD across European hemophilia centers.
Omid Seidizadeh, Ana Boban, Susie Shapiro, Riitta Lassila, Sophie Susen, Hamideh Yadegari, Laura Quintas Lorenzo, James S. O'Donnell, Giancarlo Castaman, Jeroen Eikenboom, EAHAD von Willebrand Disease Working Group   +10 more
wiley   +1 more source