Results 71 to 80 of about 3,193 (201)

Tranexamic Acid on Admission to Hospital in Hip Fracture Patients: A Scoping Review of Early Use for Reducing Blood Loss and Transfusion Risk

Emergency Care and Medicine
Background: Hip fractures are a major cause of morbidity and mortality, particularly in the elderly, and the incidence is expected to rise significantly in the coming years.
Nick D. Clement, Rosie Clement, Abigail Clement   +2 more
doaj   +1 more source

Pediatric hereditary angioedema due to C1-inhibitor deficiency

Allergy, Asthma & Clinical Immunology, 2010
Hereditary angioedema (HAE) resulting from the deficiency of the C1 inhibitor (C1-INH) is a rare, life-threatening disorder. It is characterized by attacks of angioedema involving the skin and/or the mucosa of the upper airways, as well as the intestinal
Farkas Henriette
doaj   +1 more source

A Single Smart Nanomaterial for Near‐Infrared‐Switchable Theranostics of Hemorrhage and Thrombosis via Photoacoustic Imaging

Small Science, Volume 6, Issue 11, November 2026.
A smart nanomaterial integrating Ag single atoms and nanoparticles on NiFe‐layered double hydroxides enables NIR‐switchable hemostasis and thrombolysis via photoelectric and photothermal effects. This platform allows real‐time photoacoustic imaging of active bleeding and exhibits rapid in vivo clearance, offering a dynamic theranostic strategy for ...
Yi Ye, Zhilu Sun, Daofu Wu, Jun’an Lai, Mingyue Yang, Zhiqiong Luo, Sha Cheng, Suwen Yang, Hong Zeng, Yinghui Li, Faguang Kuang, Baofei Sun, Wenxia Zhang, Xiaosheng Tang, Heng Luo, Guofeng Wu   +15 more
wiley   +1 more source

2010 Young Investigator Award winner: Therapeutic aprotinin stimulates osteoblast proliferation but inhibits differentiation and bone matrix mineralization.

, 2010
STUDY DESIGN: Analysis of the effect of antifibrinolytics on in vitro bone formation. OBJECTIVE: As the direct effect of antifibrinolytics on bone formation is unknown, we examined whether antifibrinolytics routinely used in spine surgery, namely ...
Christopher Stutz, James Edwards, Ginger Holt, Nicholas Mignemi, Jonathan Schoenecker, Heidi Hamm, Conor Lynch, Qixu Liu, Herbert Schwartz, Gregory Mencio   +9 more
core   +1 more source

Single intravenous bolus versus perioperative continuous infusion of tranexamic acid to reduce blood loss in abdominal oncosurgical procedures: A prospective randomized double-blind clinical study

Journal of Anaesthesiology Clinical Pharmacology, 2018
Background and Aims: Intraoperative use of a single bolus dose of tranexamic acid may not be sufficient to prevent bleeding in the early postoperative period. The present study was carried out to compare the effect of two dose regimens of tranexamic acid
Ramakrishna Prasad, Abhiruchi Patki, Shibany Padhy, Gopinath Ramchandran   +3 more
doaj   +1 more source

Intraoperative Hemostatic Agents in Thoracic Aortic Surgery-A Scoping Review. [PDF]

J Clin Med
Background/Objectives: Patients undergoing open thoracic aortic surgery have the highest bleeding complication rates within cardiac–vascular surgery, but research on coagulation management mostly targets general cardiac surgery. This scoping review
van Haeren MMT, Bozic C, Breel JS, Eberl S, Jamaludin FS, Veelo DP, Müller MCA, Vlaar APJ, Hermanns H.   +8 more
europepmc   +2 more sources

Lipoprotein(a), Endothelial Dysfunction and Cardiovascular Disease

Journal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.
ABSTRACT Lipoprotein(a) (Lp(a)) is a particle similar to low‐density lipoprotein cholesterol and is associated with apolipoprotein (A). High Lp(a) levels are a genetic, independent risk factor for atherosclerotic cardiovascular disease (ASCVD). Endothelial cells, which form the continuous lining of the cardiovascular system, are crucial for vascular ...
Xianghui Zhou, Xiyuan Fang, Xin Zhou, Zhao Zhang, Yu Hu, Zhipeng Cheng   +5 more
wiley   +1 more source

Consensus of the Brazilian association of hematology, hemotherapy and cellular therapy on patient blood management

Hematology, Transfusion and Cell Therapy
Patient Blood Management (PBM) is a holistic approach to managing blood as a resource of each patient; it is a multimodal strategy that is implemented using a set of techniques that can be applied in individual cases.
Maria Cristina Martins de Almeida Macedo, Silvana Biagini, Juan Carlos Montano-Pedroso, Glaciano Ribeiro, José Francisco Comenalli Marques Junior, Silvia Renata Cornélio Parolin Rizzo, Guilherme Rabello, Dante Mario Langhi Junior   +7 more
doaj   +3 more sources

The efficacy of antifibrinolytic therapy in aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis: supplementary materials

, 2023
Aim: The efficacy of antifibrinolytics in subarachnoid hemorrhage remains unclear due to conflicting evidence from studies. Materials & methods: Online databases were queried to include randomized controlled trials and propensitymatched observational ...
Muhammad Ebaad Ur Rehman (15481598), Muhammad Aemaz Ur Rehman (15481583), Salman Zubair (15481619), Ahmad Danial (15481597), Ayaz Khawaja (12733040), Umair Ahmed (10162817), Abdullah Ali Khan (15481600), Sidra Tahir (15481613), Hareem Farooq (15481586), Noor-Us-Sabah Ahmad (15481591), Kaneez Fatima (625825), Abyaz Asmar (15481584)   +11 more
core   +1 more source

Antifibrinolytics for heavy menstrual bleeding

, 2018
BACKGROUND:Heavy menstrual bleeding (HMB) is an important physical and social problem for women. Oral treatment for HMB includes antifibrinolytic drugs, which are designed to reduce bleeding by inhibiting clot-dissolving enzymes in the endometrium ...
Anne Lethaby, Hickey, Martha, Bryant-Smith, Alison C, Alison C Bryant-Smith, Lethaby, Anne, Cindy Farquhar, Martha Hickey, Farquhar, Cindy   +7 more
core   +1 more source