Results 91 to 100 of about 326,437 (300)

Astrocytic LMP2 Coordinates NF‐κB and TGF‐β1/Smad3 Signaling to Drive Neuroinflammation after Cerebral Ischemia/Reperfusion

Advanced Science, EarlyView.
ABSTRACT Astrocyte reactivity critically shapes neuroinflammatory outcomes after ischemic stroke, yet the upstream regulators governing astrocyte state transitions remain incompletely defined. Here, we identify the immunoproteasome subunit low molecular weight protein 2 (LMP2) as an important modulator of astrocyte functional remodeling following ...
Yanguang Mao, Rulan Ma, Zejing Lin, Huiying Zhao, Yuexian Liu, Yonghe Su, Xu Zhang, Xingyong Chen   +7 more
wiley   +1 more source

Screening of plant-mediated nanoparticles for antifungal activity [PDF]

, 2020
>Magister Scientiae - MScNanotechnology is spreading rapidly across the world as an extremely powerful technology. Nanoscience and nanotechnology are innovative scientific advancements that have been introduced only in this century.
de Beer, Irving
core   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Evaluation of Agronomic Performance of two Varieties of Faba Bean (Vicia faba L.), INIAP 440 - Quitumbe and INIAP 442 - Sultana, using Neutrosophic Superhypersoft sets [PDF]

Neutrosophic Sets and Systems
The yield and earliness of broad bean varieties have depended on key factors to enhance agricultural productivity in various regions. Therefore, the objective of the study focused on evaluating the agronomic yield and earliness of the INIAP 442-SULTANA ...
Karina Paola Marín Quevedo, Cristian Santiago Jiménez Jacome, Ángel Rubén Murillo Ilbay, Isabel Chávez   +3 more
doaj   +1 more source

Calcineurin‐Dependent Stress Adaptation Enables Caspofungin Heteroresistance Leading to Stable Resistance in Candida Glabrata

Advanced Science, EarlyView.
Caspofungin heteroresistance is prevalent in clinical Candida glabrata isolates and depends on calcineurin‐mediated stress adaptation. This transient phenotype serves as a reservoir for resistance evolution, enabling the emergence of stable resistant descendants under prolonged drug pressure.
Yanyu Su, Yi Li, Meng Xiao, Dan Guo, David S. Perlin, Erika Shor, Yingchun Xu, Yingxing Li   +7 more
wiley   +1 more source

Enhanced anti-infective activities of sinapic acid through nebulization of lyophilized protransferosomes

Frontiers in Nanotechnology
IndroductionCOVID-19 is a contagious illness caused by the virus SARS-CoV-2, a major cause of death globally, even with effective vaccinations. Additionally, multidrug resistant bacterial and fungal pathogens are a real threat to many healthcare settings.
Hani A. Alhadrami, Hani A. Alhadrami, Amr Gamal, Ngozi Amaeze, Ahmed M. Sayed, Mostafa E. Rateb, Demiana M. Naguib   +6 more
doaj   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Knowledge and usage patterns of clotrimazole vaginal cream and tablet amongst females: a cross-sectional study

Frontiers in Pharmacology
IntroductionClotrimazole is a broad-spectrum antimycotic agent that is primarily used to treat yeast and other fungal infections. Considering the limited number of medicines available for the treatment of vulvovaginal candidiasis, indiscriminate use of ...
Obi Peter Adigwe, Godspower Onavbavba, Chiamaka Frances Okeke   +2 more
doaj   +1 more source

Exploration of secondary metabolites from green algae as antimicrobial agents: A comprehensive review [PDF]

Botanica Serbica
A number of advancements have been made in algal technology in different fields, such as medical, cosmetic, and pharmaceutical. Green algae (Chlorophyta) are a group of photosynthetic organisms which live in both aquatic and terrestrial environments ...
Elsa Shibu Sruthy, Edathiruthi Kottukkal Chandran Baiju   +1 more
doaj   +1 more source

Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis

Advanced Science, EarlyView.
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa, Silke De Vriendt, Lixian Liu, Thalles Fernando Rocha Ruiz, Hugo Vankelecom, Christiani Andrade Amorim   +5 more
wiley   +1 more source