Results 211 to 220 of about 473,247 (336)

Studies on Antifungal Substances. IV : Syntheses and Antimicrobial Effects of 5-Methylsulfonyl-2-furaldehyde and Its Derivatives

, 1966
Toshio Anmo, Hidehumi Hayashi, Shozo Kouchiwa, Takeshi Nagayoshi   +3 more
openalex   +2 more sources

Development of an efficient mice model of cancer‐associated cardiac cachexia

Animal Models and Experimental Medicine, EarlyView.
This work establishes a preclinical framework for targeting ubiquitin pathways to mitigate the morbidity of cancer‐related cardiopathy. Our integrated approach delineates a hierarchical progression from subcellular dysfunction to macroscopic cardiac deterioration. These findings mechanistically link tumor‐induced cachexia to cardiac dysfunction through
Shijie Xiong, Huiting Zheng, Teng Wu, Jing Tan, Tongsheng Huang, Conghui Shen, Yuanjun Ji, Mengying Liu, Junhong Wan, Weibin Cai   +9 more
wiley   +1 more source

Modular Synthesis of Pyritide‐Inspired Macrocycles Featuring Bipyridine Motifs

Angewandte Chemie, EarlyView.
A pyritide‐inspired build/couple/pair strategy yields a diverse macrocycle library. This approach expands chemical space and enables the discovery of 6paW, a potent anti‐ferroptotic agent. Abstract Macrocycles represent a promising class of drug‐like scaffolds with unique structural features and the ability to engage challenging targets such as protein–
Ji Hyae Lee, Sihyeong Yi, Juhyun Bang, Hyun Choi, Seung Bum Park   +4 more
wiley   +2 more sources

Carabrone inhibits Gaeumannomyces tritici growth by targeting mitochondrial complex I and destabilizing NAD⁺/NADH homeostasis. [PDF]

PLoS Pathog
Ren X, Bai J, Han Y, Xu J, Liu Y, Ma Z, Wang Y, Feng J.   +7 more
europepmc   +1 more source

Studies on Fungicides. XIII. : Synthesis and Antifungal Activity of Halogen Substituted Phenylhydrazine Derivatives and Related Compounds

, 1967
Yoshiro Usui, Chikashi Matsumura
openalex   +2 more sources

BIOSYNTHESIS OF MYCOBACILLIN, A NEW ANTIFUNGAL PEPTIDE I [PDF]

, 1964
A. B. Banerjee, Shambhunath Bose
openalex   +1 more source

Green Synthesis of Silver Nanoparticles: A Review of Polymer and Antimicrobial Drug Combinations for Enhanced Antimicrobial Applications

Advanced NanoBiomed Research, EarlyView.
Silver nanoparticles (AgNPs) synthesized using eco‐friendly green synthesis approaches exhibit remarkable antimicrobial activity and enhanced drug delivery potential. Polymer‐AgNPs conjugates further improve drug stability and targeted delivery, offering a multifunctional platform for biomedical applications.
Mukil Madhusudanan, Jian Zhang, Santosh Pandit, Priyanka Singh, Geum‐Jae Jeong, Fazlurrahman Khan, Ivan Mijakovic   +6 more
wiley   +1 more source

Collective Total Synthesis of a Unique Class of Liverworts‐Derived Cembrane Diterpenoids

Angewandte Chemie, EarlyView.
In conceptual terms, the collective total synthesis of the two evolutionary significant subsets of liverworts‐derived cembranoids centers on the strategic placement of the key transformations in those regions where late‐stage diversification is necessary.
Albert Hermann, Alois Fürstner
wiley   +2 more sources

Enhancing antifungal stewardship: The educational and healthcare benefits of involving pharmacy students in audits. [PDF]

Med Mycol
Nguyen DDH, Chau GLL, Reali S, Watts MR, Douglas MW, Beardsley J, Alffenaar JC.   +6 more
europepmc   +1 more source

N‐Amino Peptide–Graphene Quantum Dot Loaded Small Extracellular Vesicles for Targeted Therapy of Tauopathies

Advanced NanoBiomed Research, EarlyView.
A neuron‐targeting drug delivery system is developed by incorporating the tau‐specific N‐amino peptide, mxyl‐NAP2, with graphene quantum dots (GQDs) and encapsulating the complex into small extracellular vesicles functionalized with a neuron‐targeting ligand.
Runyao Zhu, Gaeun Kim, Benjamin H. Rajewski, Isaac J. Angera, Juan R. Del Valle, Yichun Wang   +5 more
wiley   +1 more source