Results 261 to 270 of about 645,736 (382)

Antifungal drug resistance: evolution, mechanisms and impact.

open access: yesCurrent Opinion in Microbiology, 2018
Nicole M. Revie   +3 more
semanticscholar   +1 more source

Higher‐Level Structural Classification of Pseudomonas Cyclic Lipopeptides through Their Bioactive Conformation

open access: yesAdvanced Science, EarlyView.
Solution structures of a series of cyclic lipodepsipeptides from Pseudomonas reveal that these specialized metabolites adopt left‐handed alpha helical conformations of only two types, being either ‘stapled’ or ‘catch‐pole’ helix. The particular modular distribution of the biosynthetic gene clusters is found to determine the extent of their conserved ...
Benjámin Kovács   +9 more
wiley   +1 more source

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

open access: yesAdvanced Science, EarlyView.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen   +15 more
wiley   +1 more source

Editorial: Natural remedies repositioned: advancing drug discovery for infectious diseases

open access: yesFrontiers in Pharmacology
John Ogbaji Igoli   +4 more
doaj   +1 more source

Evaluation of Candida species and antifungal susceptibilities among patients with bloodstream infection

open access: gold, 2020
Ayesha Akbar   +9 more
openalex   +1 more source

A Scoping Review of Nudges for Enhancing Agricultural Policy

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT Following PRISMA guidelines, we conduct a scoping review on 18 empirical studies on nudging interventions for farmers in Europe and the USA. The evidence on the effectiveness of nudges is mixed. Some studies demonstrate positive outcomes, particularly when nudges are combined with other interventions; others report no effect or negative ...
Nadja El Benni   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy