Results 101 to 110 of about 6,322,982 (307)
mBioContemporary antifungal therapies utilized to treat filamentous fungal infections are inhibited by intrinsic and emerging drug resistance. Consequently, there is an urgent need to develop novel antifungal compounds that are effective against drug ...
Cecilia Gutierrez-Perez +13 more
doaj +1 more source
Molluscicidal and antifungal activity of diterpenoids from brown algae of the family dictyotaceae.
, 1986 17 diterpenoids isolated from brown algae of the family DICTYOTACEAE have been evaluated for molluscicidal and antifungal activity. Significant molluscicidal activity is exhibited by the two geometrical isomers 9 and 10.
Nicolosi G +3 more
core
Isolation and Characterisation of Bacterial Metabolites as Potential Wood Preservatives [PDF]
, 2012 The durability of wood has traditionally relied on the use of heavy metals and toxic compounds to deter wood degrading fungi. Conventional wood preservatives such as Chromated Copper Arsenate (CCA) have been widely used to control wood degrade for many ...
O'Callahan, Diahanna Rachelle
core
RSF1‐Dependent PAR Turnover Promotes 53BP1 Liquid Condensate Formation at DNA Damage Sites
Advanced Science, EarlyView.At sites of DNA damage, RSF1 recruits PARG to accelerate PAR turnover, triggering a switch from PAR‐driven condensates to 53BP1 condensates. This condensate transition enables p53‐dependent gene transcription and coordinates the DNA damage response.
Yungyeong Heo +10 more
wiley +1 more source
EFFECT OF EXTRACTION METHODS ON ANTIFUNGAL ACTIVITY OF SEA CUCUMBER (Stichopus japonicus)
Agritech, 2014 The objective of this study was to investigate the antifungal activity of the soluble matter (SM) and crude saponins (CS) extracted from Stichopus japonicus using pressurized solvent extraction (PSE) with water or aqueous ethanol as a solvent, in ...
Amir Husni, Il Shik Shin, Donghwa Chung
doaj +1 more source
, 2002 Maize ribosome-inactivating protein 1 (RIP1) is an abundant 32-kDa protein that can depurinate a specific adenine residue on large 28S ribosomal RNA. This irreversible modification of the ribosomal RNA inhibits translation.
Nielsen, Kirsten
core
In vitro antifungal activity of topical and systemic antifungal drugs against Malassezia species
, 2013 The strict nutritional requirements of Malassezia species make it difficult to test the antifungal susceptibility. Treatments of the chronic and recurrent infections associated with Malassezia spp. are usually ineffective. The objective of this study was
Rojas, Florencia +7 more
core +1 more source
Repurposing FDA‐Approved Drugs to Inhibit Fungal PPTases for Broad‐Spectrum Synergy
Advanced Science, EarlyView.Fungal secondary metabolites serve as crucial virulence effectors; however, the potential of their biosynthetic pathways as antifungal targets remains inadequately comprehended. Repurposed FDA‐approved drugs inhibit fungal PPTase (essential for secondary metabolism) in vivo.
Zili Song +7 more
wiley +1 more source
Synthesis and Antifungal Activity of Novel 3-Caren-5-One Oxime Esters
Molecules, 2017 A series of novel 3-caren-5-one oxime esters were designed and synthesized by multi-step reactions in an attempt to develop potent antifungal agents. Two E-Z stereoisomers of the intermediate 3-caren-5-one oxime were separated by column chromatography ...
Min Huang +4 more
doaj +1 more source
Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape
Advanced Science, EarlyView.Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim +12 more
wiley +1 more source