Results 131 to 140 of about 327,504 (360)

Identification and characterization of a novel antifungal compound tubeimoside I targeting cell wall

Microbiology Spectrum
Due to fungal diseases that threaten immunocompromised patients, along with the limited availability of antifungal agents, there is an urgent need for new antifungal compounds to treat fungal infections.
Qiannan Liu, Zhiqi Zhong, Shunxin Zheng, Yunzhuo Chu, Norihiro Sakamoto, Takayoshi Kuno, Yue Fang   +6 more
doaj   +1 more source

Hard‐Magnetic Soft Millirobots in Underactuated Systems

Advanced Robotics Research, EarlyView.
This review provides a comprehensive overview of hard‐magnetic soft millirobots in underactuated systems. It examines key advances in structural design, physics‐informed modeling, and control strategies, while highlighting the interplay among these domains.
Qiong Wang, Zixuan Zhang, Bingyan Li, Junkai Wang, Hongcheng Gu   +4 more
wiley   +1 more source

Terpenoids with antifungal activity for Candida Berkhout species, causing hospital infections

O Mundo da Saúde, 2014
The increased incidence of fungi causing nosocomial infections is associated, in general, to employment and use of broadspectrum antibiotic therapy in preterm in exposure time and stay in inpatient units.
Aírton Viriato
doaj  

In Vitro Antifungal Effect of Selected Essential Oils Against Clinical Isolates Causing Fungal Keratitis: A Preliminary Pharmacological Evaluation

Future Pharmacology
Background/Objectives: Fungal keratitis (FK) is a current challenge in ophthalmology due to its association with severe visual impairment and the limitations of current antifungal therapies.
Elijah Akegbe, Nuno Mesquita, Célia Cabral, Emília Pereira, Luís Fernandes, Anália do Carmo, Rui Tomé, Dolores Pinheiro, João Pinheiro-Costa, Andreia M. Rosa, Elisa J. Campos   +10 more
doaj   +1 more source

Apple scab control with grapefruit seed extract: no alternative to chemical fungicides [PDF]

, 2004
The growth inhibiting effect of four commercially available grapefruit seed extracts on the causal organism of apple scab Venturia inaequalis was tested.
Kelderer, Markus, Marschall, Klaus, Spitaler, Renate, Stuppner, Hermann, Zelger, Roland, Zidorn, Christian   +5 more
core  

Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors

Advanced Science, EarlyView.
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon, Kyungchul Noh, Minkyu Hwang, Yoon‐Jung Kim, Unjin Lee, Yeon Joo Ryu, Je‐Kyung Ryu, Sang Beom Jun, Se‐Young Choi, Woo‐Hyun Cho, Sung Joong Lee   +10 more
wiley   +1 more source

IN VITRO ANTIFUNGAL ACTIVITY EVALUATION OF FIVE PLANT EXTRACTS AGAINST FIVE PLANT PATHOGENIC FUNGI CAUSING RICE AND ECONOMIC CROP DISEASES [PDF]

, 2016
Arom Jantasorn, Boontida Moungsrimuangdee, Tida Dethoup   +2 more
openalex   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Human Vγ9Vδ2 T cells exhibit antifungal activity against Aspergillus fumigatus and other filamentous fungi

Microbiology Spectrum
Invasive aspergillosis (IA) and mucormycosis are life-threatening diseases, especially among immunocompromised patients. Drug-resistant Aspergillus fumigatus strains have been isolated worldwide, which can pose a serious clinical problem.
Satoru Koga, Takahiro Takazono, Hodaka Namie, Daisuke Okuno, Yuya Ito, Nana Nakada, Tatsuro Hirayama, Kazuaki Takeda, Shotaro Ide, Naoki Iwanaga, Masato Tashiro, Noriho Sakamoto, Akira Watanabe, Koichi Izumikawa, Katsunori Yanagihara, Yoshimasa Tanaka, Hiroshi Mukae   +16 more
doaj   +1 more source

Protein Language Model‐Guided Engineering of a 2,3‐Butanediol Dehydrogenase for the Enantioselective Synthesis of Cyclic α‐Hydroxy Ketones

Advanced Science, EarlyView.
A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding, Ling Jiang, Yijia Song, Zhongji Pu, Lirong Yang, Haoran Yu   +5 more
wiley   +1 more source