Results 141 to 150 of about 316,555 (354)

Magnetic Resonance Imaging‐Based Quantification of Endosomal Escape Using Iron Oxide Nanoparticle‐Loaded Lipid Nanoparticles

Advanced Healthcare Materials, EarlyView.
The therapeutic efficacy of lipid nanoparticle(LNP)‐based drugs depends on endosomal escape. However, few methods are available for quantifying the efficiency of endosomal escape in vivo. Herein, a novel method for quantifying the endosomal escape efficiency index using magnetic resonance imaging is introduced.
Somin Lee, Jeongbin Park, Han Na Jung, Shengjun Li, Zhijun Lin, Hyung‐Jun Im   +5 more
wiley   +1 more source

Antifungal effect of soil Bacillus bacteria on pathogenic species of the fungal genera Aspergillus and Trichophyton

Iranian Journal of Microbiology
Background and Objectives: The increasing prevalence of fungal infections due to antifungal resistance underscores the need for novel treatment strategies.
Mahnour Alsadat Taghavi, Maryam Ahmadi, Davoud Dehghan-Nayeri, Zahra Salehi, Masoomeh Shams-Ghahfarokhi, Fatemehsadat Jamzivar, Mehdi Razzaghi-Abyaneh   +6 more
doaj   +1 more source

Methotrexate‐Loaded Liposomal Formulation Enables 6‐Week Sustained Intraocular Therapeutic Drug Release in a Porcine Model

Advanced Healthcare Materials, EarlyView.
A liposomal formulation for methotrexate enables minimally invasive, sustained intraocular drug delivery for over six weeks with a single injection. Developed for treating intraocular diseases like lymphoma and PVR, it offers excellent biocompatibility in vivo in a porcine model.
Maximilian Hammer, Lea Skrzypczyk, Sabrina Wohlfart, Bryan Calder Ackermann, Ludwig Geisweid, Simon William Pohl, Margarita Karaivanova, Jonathan Herth, Victor Aristide Augustin, Alexander Studier‐Fischer, Tina Sackmann, Leon Kaulen, Anna Steyer, Walter Mier, David H Steel, Kanmin Xue, Gerd Uwe Auffarth, Philipp Uhl   +17 more
wiley   +1 more source

Living Materials Approach for In Situ Bio‐Polymers Production Using Bacillus Paralicheniformis in Microneedles

Advanced Healthcare Materials, EarlyView.
Dissolvable microneedle (MN) device containing Bacillus paralicheniformis. The polymeric matrix encapsulates and protects the bacteria, preserving their viability while enabling in situ production and release of γ‐polyglutamic acid. The bacteria are delivered into the skin via 500 µm‐long microneedles, and remain detectable on the skin 24 h post ...
Caroline Hali Alperovitz, Noa Ben David, Adi Gross, Boaz Mizrahi   +3 more
wiley   +1 more source

Terpenoids with antifungal activity for Candida Berkhout species, causing hospital infections

O Mundo da Saúde, 2014
The increased incidence of fungi causing nosocomial infections is associated, in general, to employment and use of broadspectrum antibiotic therapy in preterm in exposure time and stay in inpatient units.
Aírton Viriato
doaj  

Transparent Multifunctional Wearable Strain Sensor With Self‐Healing and Antibacterial Capabilities for Human Motion Detection

Advanced Healthcare Materials, EarlyView.
A transparent dual‐network strain sensor integrates robust mechanical properties, room‐temperature self‐healing, and stable performance under sub‐zero conditions and prolonged storage. Its excellent biocompatibility and antimicrobial properties enable safe skin contact.
Wenqing Chen, Wei Huang, Rohit Gupta, Abbas Heydari, Biswajoy Bagchi, Lulu Xu, Yang Xue, Eirini Velliou, Manish K Tiwari   +8 more
wiley   +1 more source

Inhibition of Penicillium digitatum by a crude extract from Solanum nigrum leaves

Biotechnologie, Agronomie, Société et Environnement, 2014
An aqueous crude extract from Solanum nigrum lyophilized leaves was evaluated for its phytochemical composition and antifungal activity against Penicillium digitatum, the causative agent of green mold of citrus fruit.
Musto, M., Potenza, G., Cellini, F.
doaj  

Identification and characterization of a novel antifungal compound tubeimoside I targeting cell wall

Microbiology Spectrum
Due to fungal diseases that threaten immunocompromised patients, along with the limited availability of antifungal agents, there is an urgent need for new antifungal compounds to treat fungal infections.
Qiannan Liu, Zhiqi Zhong, Shunxin Zheng, Yunzhuo Chu, Norihiro Sakamoto, Takayoshi Kuno, Yue Fang   +6 more
doaj   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Antifungal Activity of Some Thiosemicarbazones and Their Copper Complexes [PDF]

, 1960
B. G. Benns, B. A. Gingras, C. H. Bayley
openalex   +1 more source