Results 161 to 170 of about 6,322,982 (307)

Efficacy and safety of empagliflozin for treating neutropenia and neutrophil dysfunction in paediatric patients with glycogen storage disease type Ib: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk, Ryan Jin, Fabio Tuzzolino, Giusy Ranucci, Donatella Madonia, Alessio Provenzani   +5 more
wiley   +1 more source

Early Modern Amateur Botany and Historical Biodiversity: An Interdisciplinary Approach to the Herbarium Ruperti (1698–1705)

Berichte zur Wissenschaftsgeschichte, EarlyView.
The Herbarium Ruperti, compiled by the Lutheran theologian Georg Andreas Ruperti and containing ca. 1300 plants, represents one of the earliest comprehensive collections documenting the flora of northern Germany before the emergence of systematic botanical surveys.
Thomas Biskup
wiley   +1 more source

Combinatorial Metabolic Engineering of Alkane Biosynthesis in the Osmotolerant Yeast Debaryomyces hansenii CBS 767

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Debaryomyces hansenii is a yeast with diverse potential applications like producing oleochemicals from biomass. Yet, combinatorial metabolic engineering in D. hansenii is limited because, like many nonconventional organisms, key genomic data and genetic elements are missing. Here, we report phenotypic characterization, genomic integration loci,
Zekun Li, Nilesh Kumar Sharma, Sarah Weintraub, Eric Young   +3 more
wiley   +1 more source

Exploring the antifungal activity of the wheat microbiome. [PDF]

Biochem Soc Trans
Thatcher LF, Law SR, Dow L, Esquirol L.
europepmc   +1 more source

Antifungal activity of Cardiospermum halicacabum L. (Sapindaceae) against Trichophyton rubrum occurs through molecular interaction with fungal Hsp90

, 2018
Roberta Gaziano,1,* Elena Campione,2,* Federico Iacovelli,3 Daniele Marino,1 Francesca Pica,1 Paolo Di Francesco,1 Stefano Aquaro,4 Francesco Menichini,4 Mattia Falconi,3 Luca Bianchi2 1Microbiology Section, Department of Experimental Medicine and ...
Menichini F, Aquaro S, Pica F, Gaziano R, Di Francesco P, Bianchi L, Marino D, Iacovelli F, Falconi M, Campione E   +9 more
core  

Functional Diversity and Oleaginous Potential of Fungal Strains From Hawaiian Soil Ecosystems

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Fungi represent an important but underexplored resource for microbial lipid production, including nutritionally valuable polyunsaturated fatty acids. Hawaiian soils, shaped by volcanic parent materials and strong environmental gradients, provide a unique setting for discovering functionally diverse fungal strains with distinct metabolic traits.
Yu Wang, Adam Phelps, Zhiqing Fang, Qian Li, Ty Shitanaka, Taren Bouwman, Luke H. Amerine, Abigail Rohy, Kyla Mei A. Tuazon, Zhiyue Wang, Samir Kumar Khanal, Nhu Nguyen, Zhi‐Yan Du   +12 more
wiley   +1 more source

Design, synthesis and antifungal activity of pyrazole ester derivatives. [PDF]

RSC Adv
Shen Y, Si WJ, Feng JG, Yang WC, Wang JJ.   +4 more
europepmc   +1 more source

Enhanced antifungal activity of voriconazole-loaded nanostructured lipid carriers against Candida albicans with a dimorphic switching model

, 2017
Baocheng Tian,1 Qi Yan,1 Juan Wang,1 Chen Ding,2 Sixiang Sai1 1School of Pharmacy, Binzhou Medical University, Yantai, 2College of Life and Health Science, Northeastern University, Shenyang, People’s Republic of China Abstract: Candida commonly ...
Sai S, Yan Q, Ding C, Tian B, Wang J
core  

Multicomponent reactions for DNA‐encoded library construction: Scaffold diversity and reaction engineering strategies

Bulletin of the Korean Chemical Society, EarlyView.
Abstract DNA‐encoded libraries (DELs) enable large‐scale screening for hit identification, but accessing sp3‐rich, three‐dimensional chemotypes beyond flat, aromatic scaffolds remains challenging. Multicomponent reactions (MCRs) assemble such complexity from simple building blocks in a single step, and reaction‐engineering strategies have extended on ...
Jimin Moon, Hyemin Yoon, Kang Ju Lee, Hyun Jin Kim   +3 more
wiley   +1 more source

Nectriatides with No Antifungal Activity Bind to Ergosterol and Potentiate the Antifungal Activity of Amphotericin B against <i>Candida albicans</i>. [PDF]

ACS Omega
Kobayashi K, Miyake R, Nagai K, Sato Y, Seki R, Sakai-Kato K, Nishimura S, Ohshiro T, Tomoda H.   +8 more
europepmc   +1 more source