Results 191 to 200 of about 316,555 (354)

Dual Disruption of the Immune Cytokine Spätzle Facilitates Fungal Infection of Diverse Insect Hosts

open access: yesAdvanced Science, EarlyView.
The Toll pathway is essential for insect defense against fungal pathogens. This works reports that fungal parasites employ two divergent virulent effectors to target the Toll receptor ligand Spätzle: a metalloprotease degrading it and a hairpin‐like effector hijacking it to block signal transduction. This dual strategy enables the fungus to kill a wide
Shuangxiu Song   +7 more
wiley   +1 more source

<i>Ascosphaera apis</i> as a target for the antifungal activity of symbiotic Bifidobacteria in honey bees. [PDF]

open access: yesFront Insect Sci
Iorizzo M   +11 more
europepmc   +1 more source

Fundamental Studies on Antifungal Activity of Griseofulvin

open access: bronze, 1961
Akira Matsuda   +3 more
openalex   +2 more sources

AP2M1 Amplification Orchestrates Notch‐Mediated Chemoresistance in Hematopoietic Stem Cells of Acute Myeloid Leukemia Patients

open access: yesAdvanced Science, EarlyView.
The precise regulation of AP2M1 is essential for normal hematopoiesis. Overexpression of AP2M1 negatively affects the clinical outcomes of AML patients. Upregulation of AP2M1 enhances stemness and chemoresistance in HSPC cells of AML. AP2M1 modulates NOTCH1 expression, enhancing the Notch1 signaling pathway.
Hansong Lee   +28 more
wiley   +1 more source

A Scoping Review of Nudges for Enhancing Agricultural Policy

open access: yesApplied Economic Perspectives and Policy, EarlyView.
ABSTRACT Following PRISMA guidelines, we conduct a scoping review on 18 empirical studies on nudging interventions for farmers in Europe and the USA. The evidence on the effectiveness of nudges is mixed. Some studies demonstrate positive outcomes, particularly when nudges are combined with other interventions; others report no effect or negative ...
Nadja El Benni   +4 more
wiley   +1 more source

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