Results 71 to 80 of about 11,634,387 (360)

Antifungal Activity of Micafungin in Serum [PDF]

Antimicrobial Agents and Chemotherapy, 2009
ABSTRACT We have evaluated the antifungal activity of micafungin in serum by using the disk diffusion method with serum-free and serum-added micafungin standard curves. Serum samples from micafungin-treated patients have been shown to exhibit adequate antifungal activity, which was in proportion to both the applied dose and the actual ...
Jun, Ishikawa, Tetsuo, Maeda, Itaru, Matsumura, Masato, Yasumi, Hidetoshi, Ujiie, Hiroaki, Masaie, Tsuyoshi, Nakazawa, Nobuo, Mochizuki, Satoshi, Kishino, Yuzuru, Kanakura   +9 more
openaire   +2 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Antifungal and antioxidant activity of fatty acid methyl esters from vegetable oils

Anais da Academia Brasileira de Ciências, 2017
Fatty acid methyl esters (FAMEs) were obtained from vegetable oils of soybean, corn and sunflower. The current study was focused on evaluating the antifungal activity of FAMEs mainly against Paracoccidioides spp., as well as testing the interaction of ...
MARIA E.A. PINTO, STHÉFANE G. ARAÚJO, MARCELA I. MORAIS, NÍVEA P. SÁ, CAROLINE M. LIMA, CARLOS A. ROSA, EZEQUIAS P. SIQUEIRA, SUSANA JOHANN, LUCIANA A.R.S. LIMA   +8 more
doaj   +1 more source

Antifungal Activity of Maytenin and Pristimerin [PDF]

Evidence-Based Complementary and Alternative Medicine, 2012
Fungal infections in humans have increased alarmingly in recent years, particularly in immunocompromised individuals. Among the infections systemic candidiasis, aspergillosis, cryptococcosis, paracoccidioidomycosis, and histoplasmosis mortality are more prevalent and more severe in humans.
Gullo, Fernanda P., Sardi, Janaina C. O., Santos, Vania A. F. F. M., Sangalli-Leite, Fernanda, Pitangui, Nayla S., Rossi, Suelen A., de Paula e Silva, Ana C. A., Soares, Luciana A., Silva, Julhiany F., Oliveira, Haroldo C., Furlan, Maysa, Silva, Dulce H. S., Bolzani, Vanderlan da Silva, Mendes-Giannini, Maria José Soares, Fusco-Almeida, Ana Marisa   +14 more
openaire   +4 more sources

In vitro antifungal activity of topical and systemic antifungal drugs against Malassezia species [PDF]

, 2013
The strict nutritional requirements of Malassezia species make it difficult to test the antifungal susceptibility. Treatments of the chronic and recurrent infections associated with Malassezia spp. are usually ineffective. The objective of this study was
Rojas, Florencia, Carrillo‐Muñoz, Alfonso Javier, Giusiano, Gustavo, Sosa, María de los Ángeles, Martín Espada, María Del Carmen, Paya Vicens, María Jesús, Tur‐Tur, Cristina, Ortiz Díez, Gustavo   +7 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Antibacterial and antifungal activity of the liverwort (Ptilidium pulcherrimum) methanol extract [PDF]

Archives of Biological Sciences, 2010
The antimicrobial activity of the methanol extract from the liverwort, Ptilidium pulcherrimum was evaluated against five bacterial and six fungal species. In vitro antibacterial activity was assessed by disc diffusion and microdilution methods.
Veljić M., Ćirić Ana, Soković Marina, Janaćković P., Marin P.D.   +4 more
doaj   +1 more source

ZIF-8 encapsulation improves the antifungal activity of benzaldehyde and methyl anthranilate in films [PDF]

, 2023
Two ZIF-8-based biocomposites are obtained by entrapping antifungal benzaldehyde and methyl anthranilate biomolecules via direct impregnation with high payloads. Enhanced antifungal activity against Penicilium expansum is shown after their integration in
Raquel , Heras-Mozos, Rafael, Gavara, Katia, Caamaño, Jana, Glatz, Pilar , Hernández- Muñoz, Gracia, López-Carballo, Mónica, Giménez-Marqués   +6 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Synthesis and Antimicrobial Screening of Some Novel 2, 5-Disubstituted 1, 3, 4-oxadiazole Derivatives

E-Journal of Chemistry, 2011
The syntheses of series of 2, 5-disubstituted 1, 3, 4-oxadiazole derivatives are described. A total of twelve new compounds were synthesized and characterized by IR, 1H-NMR and Mass spectral data.
P. Panneerselvam, G. Geete Ganesh
doaj   +1 more source