Results 91 to 100 of about 223,964 (346)
Advanced Healthcare Materials, EarlyView.A transparent dual‐network strain sensor integrates robust mechanical properties, room‐temperature self‐healing, and stable performance under sub‐zero conditions and prolonged storage. Its excellent biocompatibility and antimicrobial properties enable safe skin contact.
Wenqing Chen +8 more
wiley +1 more source
Isolation, characterization and selection of bacterial isolates from a suppressive soil with beneficial traits to plants [PDF]
, 2017 Backgrounds This study focused on the characterization and selection of bacterial strains obtained from a suppressive soil displaying antifungal activity against the soilborne phytopathogenic fungi Rosellinia necatrix.
Cazorla-Lopez, Francisco Manuel +4 more
core
Repurposing of terconazole as an anti Trypanosoma cruzi agent [PDF]
, 2019 Trypanosoma cruzi is the causative agent of Chagas disease, a parasitic infection endemic in Latin America. Currently there are no effective treatments for the chronic phase of the disease, when most patients are diagnosed, therefore the development of ...
Martínez Sayé, Melisa Soledad +4 more
core +1 more source
Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Advanced Healthcare Materials, EarlyView.Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
APX001 Is Effective in the Treatment of Murine Invasive Pulmonary Aspergillosis. [PDF]
, 2019 Invasive pulmonary aspergillosis (IPA) due to Aspergillus fumigatus is a serious fungal infection in the immunosuppressed patient population. Despite the introduction of new antifungal agents, mortality rates remain high, and new treatments are needed ...
Alkhazraji, Sondus +7 more
core
Calli Essential Oils Synergize with Lawsone against Multidrug Resistant Pathogens. [PDF]
, 2017 The fast development of multi-drug resistant (MDR) organisms increasingly threatens global health and well-being. Plant natural products have been known for centuries as alternative medicines that can possess pharmacological characteristics, including ...
Alsaadi, Abrar I +6 more
core +2 more sources
Antifungal agents: Polyene, azole, antimetabolite, other and future agents
Journal of Basic Research in Medical Sciences, 2018 Antifungals have always been considered as one of the astonishing discoveries of the 20th century. This is correct, but the real marvel is the development of antifungal resistance in hospitals, communities, and the environment concomitant with their use.
Fardin Ali Malayeri +2 more
doaj
Memorias do Instituto Oswaldo Cruz, 2012 The extensive use of azole antifungal agents has promoted the resistance of Candida spp to these drugs. Candida glabrata is a problematic yeast because it presents a high degree of primary or secondary resistance to fluconazole. In Brazil, C.
Débora Alves Nunes Mario +6 more
doaj +1 more source
Marine Bioactive Compounds against Aspergillus fumigatus: Challenges and Future Prospects
Antibiotics, 2020 With the mortality rate of invasive aspergillosis caused by Aspergillus fumigatus reaching almost 100% among some groups of patients, and with the rapidly increasing resistance of A.
Chukwuemeka Samson Ahamefule +7 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Photosensitizing lipid nanoparticles (PLNPs) are engineered by incorporating cholesterol–PEG–pheophorbide a into MC3‐based LNPs and encapsulating GPX4‐targeting siRNA. Upon light activation, PLNPs generate reactive oxygen species (ROS) while silencing GPX4 to induce ferroptosis.
Ga‐Hyun Bae +9 more
wiley +1 more source