Results 1 to 10 of about 22,252 (260)

Predictors of choice of initial antifungal treatment in intraabdominal candidiasis [PDF]

, 2016
Intraabdominal candidiasis (IAC) is the second most frequent form of invasive candidiasis, and is associated with high mortality rates. This study aims to identify current practices in initial antifungal treatment (IAT) in a real-world scenario and to ...
Almirante, B., Ansaldi, F., Antonelli, M., Baldin, G., Bassetti, Matteo, Borgatta, B., Bouza, E., Brugnaro, P., Busetti, M., Colombo, A. L., de Egea, V., De Pascale, G., Del Bono, V., Diaz Martin, A., Dimopoulos, G., Esteves, P., Esteves, P., Garnacho Montero, J., Grandesso, S., Lagunes, L., Luzzati, R., Mart\uedn Gomez, M. T., Martin, M. T., Menichetti, F., Menichetti, F., Merelli, M., Mesini, A., Mu\uf1oz, P., Nou\ue9r, S. A., Nucci, M., Palacios Garcia, I., Pelaez, T., Posteraro, B., Pumarola, T., Raise, E., Rello, J., Rey P\ue9rez, A., Righi, E., Rosin, C., Sanguinetti, M., Sartor, A., Scarparo, C., Scarparo, C., Scotton, G., Sganga, G., Tagliaferri, E., Tascini, C., Trucchi, C., Tumbarello, M., Vena, A., Viscoli, C.   +50 more
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Antifungal Therapy: New Advances in the Understanding and Treatment of Mycosis [PDF]

, 2017
The high rates of morbidity and mortality caused by fungal infections are associated with the current limited antifungal arsenal and the high toxicity of the compounds.
Ana C. A. de Paula e Silva, Ana M. Fusco-Almeida, Caroline B. Costa-Orlandi, Caroline M. Marcos, Haroldo C. de Oliveira, Liliana Scorzoni, Maria J. S. Mendes-Giannini, Patrícia A. Assato, Wanessa C. M. A. de Melo   +8 more
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SIGNIFICANCE OF YEASTS IN BLOODSTREAM INFECTION: EPIDEMIOLOGY AND PREDISPOSING FACTORS OF CANDIDAEMIA IN ADULT PATIENTS AT A UNIVERSITY HOSPITAL (2010-2014) [PDF]

, 2015
The incidence of Candida bloodstream infection (BSI) has increased during the past decades. Species distribution is changing worldwide, and non-albicans Candida spp. are becoming more prevalent.
Iván, Miklós, Juhász, Emese, Kristóf, Katalin, Pongrácz, Júlia   +3 more
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Accuracy of Sensititre YeastOne echinocandins epidemiological cut-off values for identification of FKS mutant Candida albicans and Candida glabrata: a ten year national survey of the Fungal Infection Network of Switzerland (FUNGINOS).

Clinical Microbiology and Infection, 2018
OBJECTIVES Echinocandins represent the first-line treatment of candidaemia. Acquired echinocandin resistance is mainly observed among Candida albicans and Candida glabrata and is associated with FKS hotspot mutations. The commercial Sensititre YeastOne™ (
A. Kritikos, D. Neofytos, N. Khanna, P. Schreiber, K. Boggian, Jacques Bille, Jacques Schrenzel, Konrad Mühlethaler, R. Zbinden, T. Bruderer, D. Goldenberger, Gaby E. Pfyffer, A. Conen, C. Delden, S. Zimmerli, D. Sanglard, D. Bachmann, Oscar Marchetti, F. Lamoth, T. Bregenzer, Ursula Fluckiger, C. Orasch, U. Heininger, M. Franciolli, Lauro Damonti, M. Rothén, C. Zellweger, Philip E. Tarr, Felix Fleisch, C. Chuard, V. Erard, S. Emonet, J. Garbino, D. Genné, P. Bochud, T. Calandra, J. Chave, Peter Graber, R. Monotti, O. Regionale, E. Bernasconi, O. Civico, M. Rossi, M. Krause, R. Piso, F. Bally, N. Troillet, G. Eich, J. Gubler, Jan Fehr, A. Imhof, Christian Ruef, Christoph Berger, H. Fankhauser, I. Heinzer, Reno Frei, R. Hertel, M. Dolina, O. Petrini, O. Dubuis, S. Graf, M. Risch, E. Ritzler, D. Fracheboud, P. Rohner, R. Lienhardt, C. Andreutti-Zaugg, A. Gallusser, K. Herzog, U. Schibli, L. Tissière, D. Schultze   +71 more
semanticscholar   +1 more source

Portrait of matrix gene expression in Candida glabrata biofilms with stress induced by different drugs [PDF]

, 2018
(1) Background: Candida glabrata is one of the most significant Candida species associated with severe cases of candidiasis. Biofilm formation is an important feature, closely associated with antifungal resistance, involving alterations of gene ...
Henriques, Mariana, Rodrigues, Célia F.
core   +2 more sources

Role of FKS Gene in the Susceptibility of Pathogenic Fungi to Echinocandins.

Medical Mycology Journal, 2018
Echinocandins are antifungal agents that specifically inhibit the biosynthesis of 1,3-β-D-glucan, a major structural component of fungal cell walls.
Y. Hori, K. Shibuya
semanticscholar   +1 more source

Susceptibility testing of Candida glabrata clinical strains to echinocandins using SensititreTM YeastOneTM system [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2018
Objective. To determine susceptibility of C. glabrata isolates to anidulafungin, caspofungin and micafungin using the SensititreTM YeastOneTM system. Materials and Methods. C. glabrata isolates were taken prospectively from clinical specimens or from
Veselov A.V., Vasilyeva N.V., Bogomolova T.S., Raush E.R., Kutsevalova O.Yu., Nizhegorodceva I.A., Petrova L.V., Shmidt N.V., Moskvitina E.N., Sukhorukova M.V., Ivanchik N.V., Kozlov R.S.   +11 more
doaj  

Candida glabrata : a review of its features and resistance [PDF]

, 2014
Candida species belong to the normal microbiota of the oral cavity and gastrointestinal and vaginal tracts, and are responsible for several clinical manifestations, from mucocutaneous overgrowth to bloodstream infections.
A Chakrabarti, A Chakrabarti, A Kalkanci, A Kramer, A Peñas De Las, A Roetzer, A Roetzer, A Roetzer, A Roetzer, A Thierry, AA Almeida de, AL Colombo, AM Calcagno, AM Nicola, AW Segal, B Dujon, B Guo, B Klempp-Selb, BB Magee, BD Alexander, BP Cormack, C Lass-Flörl, C Marcos-Arias, C. F. Rodrigues, CJ Seneviratne, CS Kaufmann, CS Lim, CT Hittinger, CY Lin, D Dyk van, D Wilson, DA Stead, DC Sheppard, DJ Klionsky, DJ Klionsky, DM Kuhn, DR Reagan, EA Kraneveld, EJ Helmerhorst, EJ Helmerhorst, EK Bethea, EM Kojic, F Bambeke Van, F Barchiesi, F Hasan, FC Odds, FG Oppenheim, FG Oppenheim, G Butler, G Butler, G Luo, G Luo, G Ramage, G Ramage, GM Cox, GR Thompson 3rd, H Muller, H Tsai, H Urk Van, H Wisplinghoff, HM Bandara, HT Taff, I Castaño, I Iraqui, J Chandra, J Chandra, J Kim, J Lee, JA Hagerty, JA Jayatilake, JA Noble, JA Vazquez, JA Vazquez, JCO Sardi, JE Bennett, JH Shin, JL Vincent, JP Vermitsky, JR Blankenship, K Gulshan, K Lewis, K Lewis, K Seider, K Ueno, KE Caudle, KH Chen, KH Wolfe, KJ Verstrepen, KW Henry, L Vale-Silva, LP Samaranayake, LP Samaranayake, M Bassetti, M Edgerton, M Negri, M Niimi, M Niimi, M Riera, M Sikora, M Tscherner, M. Henriques, MA Al-Fattani, MA Pfaller, MA Pfaller, MA Pfaller, MC Arendrup, MC Lorenz, MD LaFleur, MD Lafleur, MN Rai, N Berila, NK Tamura, O Bader, P Gutiérrez-Escribano, P Perumal, P Shahi, P Sundstrom, P Uppuluri, P Vandeputte, P Vandeputte, PL Fidel Jr, PW Groot De, R Domergue, R Kaur, R Kaur, R Kaur, R Rajendran, RA Akins, RA Calderone, RD Cannon, RK Shields, S Brunke, S Brunke, S Farahyar, S Ferrari, S Ferrari, S Hawser, S Paul, S Silva, S Silva, S Silva, S Silva, S Silva, S. Silva, SC Halliwell, SP Hawser, SY Ruan, T Miyazaki, T Saijo, TFC Mah, V Krcmery, V Krcmery, V Mohan das, Y Nakagawa, Z Jandric, Z Xie   +155 more
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Yeast infections in sterile body fluids: species distribution, antifungal susceptibility, and cross-cutting risk factors for fungemia, sepsis, and mortality (2019–2023)

Frontiers in Microbiology
BackgroundYeast infections from sterile body fluids are increasingly encountered in tertiary care, yet contemporary links between species ecology, antifungal susceptibility, and patient outcomes remain underdefined.MethodsWe conducted a retrospective ...
Jiaxing Liu, Mei Han, Fan Yang, Shuo Gao, Wanqing Zhou, Han Shen, Xiaoli Cao, Yan Zhang   +7 more
doaj   +1 more source

Profound cell wall remodeling in Candida parapsilosis during systemic infection confers simultaneous tolerance to echinocandins and host immunity

Microbiology Spectrum
Antifungal tolerance can promote the emergence of resistance yet often incurs fitness costs for fungal pathogens. How tolerant populations compensate for these deficits and how they may be therapeutically targeted remain poorly understood.
Farnaz Daneshnia, Liuyang Cai, Deepika Gunasekaran, Isha Gautam, Austin M. Perry, Pegah Mosharaf Ghahfarokhy, Arefeh Ebadati, Julieta Munoz, Dorian Padilla, Süleyha Hilmioglu-Polat, Shenglin Mei, Daniel J. Floyd, Miquel Àngel Schikora-Tamarit, Diego Fuentes, Maria Artigues-Lleixà, Louise A. Walker, Samuel M. Gonçalves, Mostafa Salehi, Agostinho Carvalho, Jigar V. Desai, David S. Perlin, Carol A. Munro, Alex Hopke, Tuo Wang, Toni Gabaldón, Wenjie Fang, Clarissa J. Nobile, Michael K. Mansour, Amir Arastehfar   +28 more
doaj   +1 more source