Results 1 to 10 of about 10,643 (119)

Yeast infections in sterile body fluids: species distribution, antifungal susceptibility, and cross-cutting risk factors for fungemia, sepsis, and mortality (2019–2023) [PDF]

Frontiers in Microbiology
BackgroundYeast infections from sterile body fluids are increasingly encountered in tertiary care, yet contemporary links between species ecology, antifungal susceptibility, and patient outcomes remain underdefined.MethodsWe conducted a retrospective ...
Jiaxing Liu, Mei Han, Fan Yang, Shuo Gao, Wanqing Zhou, Han Shen, Xiaoli Cao, Yan Zhang   +7 more
doaj   +2 more sources

Efficacy and safety of triazoles versus echinocandins in the treatment of invasive aspergillosis: A meta-analysis [PDF]

Vojnosanitetski Pregled, 2020
Backgroun/Aim. Although majority of guidelines recommend triazoles (voriconazole, posaconazole, itraconazole and isavuconazole) as first-line therapeutic option for treatment of invasive aspergillosis, echinocandins (caspofungin, micafungin and ...
Uzelac Sanja M., Živković-Zarić Radica S., Radovanović Milan R., Ranković Goran Ž., Jankovic Slobodan M.   +4 more
doaj   +1 more source

Case Report: Echinocandin-Resistance Candida glabrata FKS Mutants From Patient Following Radical Cystoprostatectomy Due to Muscle-Invasive Bladder Cancer

Frontiers in Oncology, 2021
Invasive Candida glabrata infections are not common complications after radical cystoprostatectomy. Furthermore, resistance to echinocandins arising during the course of a patient’s treatment is rarely recognised.
Maria Szymankiewicz, Krzysztof Kamecki, Sylwia Jarzynka, Anna Koryszewska-Bagińska, Gabriela Olędzka, Tomasz Nowikiewicz, Tomasz Nowikiewicz   +6 more
doaj   +1 more source

The current place of echinocandins in the treatment and prophylaxis of invasive fungal infections [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2020
Invasive fungal infections continue to show steady growth among various patient populations, accompanied by high rates of both morbidity and attributive mortality.
Veselov A.V.
doaj   +1 more source

Evaluation of Fluconazole versus Echinocandins for Treatment of Candidemia Caused by Susceptible Common Candida Species: A Propensity Score Matching Analysis

Journal of Fungi, 2023
This study aimed to evaluate the effectiveness of fluconazole and echinocandins in the treatment of candidemia caused by both fluconazole- and echinocandin-susceptible common Candida species. A retrospective study which enrolled adult candidemia patients
Jong Hun Kim, Jin Woong Suh, Min Ja Kim
doaj   +1 more source

In Vitro Characterization of Twenty-One Antifungal Combinations against Echinocandin-Resistant and -Susceptible Candida glabrata

Journal of Fungi, 2021
This study was designed to analyze the interaction of 21 antifungal combinations consisting of seven major antifungal agents against 11 echinocandin- susceptible and six-resistant C. glabrata isolates. The combinations were divided into five major groups
Hazim O. Khalifa, Hidetaka Majima, Akira Watanabe, Katsuhiko Kamei   +3 more
doaj   +1 more source

Review on Current Status of Echinocandins Use

Antibiotics, 2020
Fungal infections are rising all over the world every year. There are only five medical compound classes for treatment: triazoles, echinocandins, polyenes, flucytosine and allylamine.
Martyna Mroczyńska, Anna Brillowska-Dąbrowska   +1 more
doaj   +1 more source

Pharmacoeconomic analysis of antifungal therapy for primary treatment of invasive candidiasis caused by Candida albicans and non-albicans Candida species

BMC Infectious Diseases, 2017
Background Cost-effectiveness studies of echinocandins for the treatment of invasive candidiasis, including candidemia, are rare in Asia. No study has determined whether echinocandins are cost-effective for both Candida albicans and non-albicans Candida ...
Huang-Tz Ou, Tsung-Ying Lee, Yee-Chun Chen, Claudie Charbonneau   +3 more
doaj   +1 more source

FKS1 Is Required for Cryptococcus neoformans Fitness In Vivo: Application of Copper-Regulated Gene Expression to Mouse Models of Cryptococcosis

mSphere, 2022
There is an urgent need for new antifungals to treat cryptococcal meningoencephalitis, a leading cause of mortality in people living with HIV/AIDS. An important aspect of antifungal drug development is the validation of targets to determine whether they ...
Sarah R. Beattie, Andrew J. Jezewski, Laura C. Ristow, Melanie Wellington, Damian J. Krysan   +4 more
doaj   +1 more source

Susceptibility of the Candida haemulonii Complex to Echinocandins: Focus on Both Planktonic and Biofilm Life Styles and a Literature Review

Journal of Fungi, 2020
Candida haemulonii complex (C. haemulonii, C. duobushaemulonii and C. haemulonii var. vulnera) is well-known for its resistance profile to different available antifungal drugs.
Lívia S. Ramos, Laura N. Silva, Marta H. Branquinha, André L. S. Santos   +3 more
doaj   +1 more source