Results 31 to 40 of about 12,522 (211)

Some issues of the resistance of Candida glabrata to echinocandins [PDF]

Клиническая микробиология и антимикробная химиотерапия, 2019
Invasive candidiasis is a common, severe and often difficult to treat complication in various categories of patients. Despite the fact that in most cases Candida albicans retains a leading position as an etiological cause, a pathogen such as Candida ...
Veselov A.V.
doaj   +1 more source

Functional Genomic Screening Reveals Core Modulators of Echinocandin Stress Responses in Candida albicans

Cell Reports, 2018
Summary: Candida albicans is a leading cause of death due to fungal infection. Treatment of systemic candidiasis often relies on echinocandins, which disrupt cell wall synthesis. Resistance is readily acquired via mutations in the drug target gene, FKS1.
Tavia Caplan, Elizabeth J. Polvi, Jinglin L. Xie, Shoshana Buckhalter, Michelle D. Leach, Nicole Robbins, Leah E. Cowen   +6 more
doaj   +1 more source

The Elevated Endogenous Reactive Oxygen Species Contribute to the Sensitivity of the Amphotericin B-Resistant Isolate of Aspergillus flavus to Triazoles and Echinocandins

Frontiers in Microbiology, 2021
Aspergillus flavus has been frequently reported as the second cause of invasive aspergillosis (IA), as well as the leading cause in certain tropical countries.
Tianyu Liang, Wei Chen, Xinyu Yang, Qiqi Wang, Zhe Wan, Ruoyu Li, Wei Liu   +6 more
doaj   +1 more source

Pharmacotherapy of Candida Infections with Echinocandins [PDF]

, 2009
The classic recommended antifungal agents for the treatment of invasive Candida infections were amphotericin B, a lipid formulation of amphotericin B and fluconazole in both neutropenic or nonneutropenic patients as either primary or alternative ...
Javier Pemán, Estrella Martin-Mazuelos, Emilia Canton, Ana Espinel-Ingroff   +3 more
core   +1 more source

Susceptibility of Pneumocystis to Echinocandins in Suspension and Biofilm Cultures [PDF]

, 2011
The targeted inhibition of cyst but not trophic development by anidulafungin, caspofungin, and micafungin on Pneumocystis murina and Pneumocystis carinii in rodent models of Pneumocystis ...
Margaret S. Collins, Melanie T. Cushion
core   +1 more source

Comparative effectiveness of echinocandins and liposomal amphotericin B for fluconazole-resistant <i>Candida parapsilosis</i> bloodstream infections. [PDF]

Antimicrob Agents Chemother
Current therapeutic options for fluconazole-resistant Candida parapsilosis (FLZR-CP) bloodstream infections (BSI) are limited to echinocandins and liposomal amphotericin B (L-AmB).
Vena A, Bartalucci C, Muccio M, Tiseo G, Muñoz P, Cesaretti M, Di Pilato V, Marchese A, Barbieri R, Forniti A, Giacobbe DR, Limongelli A, Lupetti A, Mikulska M, Salmanton-García J, Soriano Martín A, Taramasso L, Valerio M, Escribano P, Guinea J, Bouza E, Falcone M, Bassetti M, ESCMID Fungal Infection Study Group (EFISG).   +23 more
europepmc   +2 more sources

ECHINOCANDINS VERSUS DATED ANTIFUNGALS IN COMBINATION AGAINST OPPORTUNISTIC MYCOTIC INFECTIONS [PDF]

, 2017
Scientific and clinical reports globally demonstrated that the opportunistic mycotic infections are at major risk to the human fitness. In past few decades, development of resistance in microbes to existing antifungals, has emphasized on the search of ...
Chhillar Ak, Balhara, Meenakshi, Chaudhary, Renu, Narwal, Mrridula Dangi, Renu Chaudhary, Meenakshi Balhara, Ak, Chhillar, Mrridula Dangi Narwal   +7 more
core   +2 more sources

Comparative evaluation of Sensititre YeastOne and CLSI M38-Ed3 reference method for determining echinocandin minimum effective concentrations against Aspergillus isolates

Microbiology Spectrum
The minimum inhibitory concentration (MIC) of echinocandins against Aspergillus spp. does not represent the actual inhibition threshold of echinocandins.
Assaf Potruch, Hila Elinav, Matan J. Cohen, Alexander Rouvinski, Itzhack Polacheck, Maya Korem   +5 more
doaj   +1 more source

An Overview of Recent Possibilities in Pharmacotherapy of Diseases of the Oral Mucosa, Salivary Glands, and Periodontal Tissue

Česká Stomatologie a Praktické Zubní Lékařství, 2013
Introduction: A review of newer drugs for topical or systemic administration useful in contemporary dentistry in the therapy of diseases of periodontal tissue, oral mucous membrane, and salivary glands available in Czech Republic was given in this ...
R. Slezák, I. Lindrová, V. Buchta, V. Paulusová, Z. Šustová, O. Kopecký, L. Ryšková   +6 more
doaj   +1 more source

Cdc14 phosphatase contributes to cell wall integrity and pathogenesis in Candida albicans

Frontiers in Microbiology, 2023
The Cdc14 phosphatase family is highly conserved in fungi. In Saccharomyces cerevisiae, Cdc14 is essential for down-regulation of cyclin-dependent kinase activity at mitotic exit.
Kedric L. Milholland, Ahmed AbdelKhalek, Kortany M. Baker, Smriti Hoda, Andrew G. DeMarco, Noelle H. Naughton, Angela N. Koeberlein, Gabrielle R. Lorenz, Kartikan Anandasothy, Antonio Esperilla-Muñoz, Sanjeev K. Narayanan, Jaime Correa-Bordes, Scott D. Briggs, Scott D. Briggs, Mark C. Hall, Mark C. Hall   +15 more
doaj   +1 more source