Results 51 to 60 of about 12,522 (211)

Candida parapsilosis Virulence and Antifungal Resistance Mechanisms: A Comprehensive Review of Key Determinants

Journal of Fungi, 2023
Candida parapsilosis is the second most common Candida species isolated in Asia, Southern Europe, and Latin America and is often involved in invasive infections that seriously impact human health. This pathogen is part of the psilosis complex, which also
Joana Branco, Isabel M. Miranda, Acácio G. Rodrigues   +2 more
doaj   +1 more source

Echinocandins for management of invasive candidiasis in patients with liver disease and liver transplantation [PDF]

, 2018
Siang Fei Yeoh,1 Tae Jin Lee,2 Ka Lip Chew,3 Stephen Lin,4 Dennis Yeo,5 Sajita Setia5 1Department of Pharmacy, National University Health System, Singapore, Singapore; 2Department of Pharmacy, National University of Singapore, Singapore, Singapore ...
Yeo D, Lee TJ, Lin S, Chew KL, Yeoh SF, Setia S   +5 more
core  

An Update on Invasive Fungal Infections in Solid Organ Transplant Recipients

Transplant Infectious Disease, EarlyView.
ABSTRACT Invasive fungal infections (IFI) remain a significant infection‐related complication in solid organ transplant recipients (SOTRs), the incidence of which has not changed overtime. With a focus on studies and data published after 2019, this narrative review provides an update on the epidemiology and prevention of IFIs in SOTRs and highlights ...
Tina Marinelli, Shahid Husain
wiley   +1 more source

Successful management of recalcitrant fungal keratitis with topical caspofungin

GMS Ophthalmology Cases, 2022
Objective: To report a case of recalcitrant fungal keratitis successfully managed with topical caspofungin acetate in North India.Methods: Case report and literature review.Results: An 18-year-old male patient presented with complaints of redness ...
Goel, Siddhi, Sharma, Arpit, Sinha, Rajesh   +2 more
doaj   +1 more source

Micafungin: a sulfated echinocandin [PDF]

The Journal of Antibiotics, 2009
Micafungin is the second approved antifungal agent in the echinocandin series and is now used worldwide in chemotherapy for life-threatening fungal infections. It is water-soluble and is semi-synthesized from the acylated cyclic hexapeptide FR901379, a natural product from the fungus Coleophoma empetri F-11899, through enzymatic deacylation of FR901379,
openaire   +2 more sources

Gold Nanoparticles Coated With the Antimicrobial Peptide Os‐C(W5): Anticandidal and Biological Activity

Journal of Peptide Science, Volume 32, Issue 9, September 2026.
Gold nanoparticles conjugated with a tick‐derived antimicrobial peptide, Os‐C(W5), demonstrate enhanced proteolytic stability and potent antifungal activity against Candida albicans biofilms and planktonic cells. These non‐cytotoxic nanoconjugates represent a promising biocompatible strategy for combating resistant fungal infections while maintaining ...
P. J. Palm, R. R. Chirombo, C. K. Chiramba, J. C. Serem, H. Taute, M. van der Walt, A. R. M. Gaspar, M. J. Bester   +7 more
wiley   +1 more source

Improvement in Outcomes of Childhood Acute Myeloid Leukemia Treatment: A Survival Analysis at a Reference University Hospital in Rio de Janeiro, Brazil

Cancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Acute myeloid leukemia (AML) represents 15% to 20% of all pediatric acute leukemias and is responsible for nearly 30% of deaths in this population. While high‐income countries report overall survival (OS) rates near 75%, survival in Brazil remains significantly lower, ranging between 30% and 40%.
Thais Alcantara Bonilha, Deborah Sutter Ayres Pereira, Alice Maria Boulhosa de Azevedo, Adriana Martins de Sousa, Elaine Sobral da Costa, Marcelo Gerardin Poirot Land   +5 more
wiley   +1 more source

Potential Microbiological Effects of Higher Dosing of Echinocandins. [PDF]

, 2015
The antifungal "paradoxical effect" has been described as the reversal of growth inhibition at high doses of echinocandins, most usually caspofungin.
Steinbach, W.J., Lamoth, F., Juvvadi, P.R.   +2 more
core   +1 more source

Effects of the HDAC6/8 Inhibitor MC1568, Alone and in Combination With Fluconazole, in Non‐Albicans Candida Species Infections

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
This study explores new antifungal strategies to combat non‐albicans Candida species. We tested clinically approved HDAC inhibitors—Vorinostat, Romidepsin, Tucidinostat—and the HDAC6/8‐selective MC1568, alone and with Fluconazole. The Fluconazole/MC1568 combination significantly enhanced antifungal activity and reduced biofilm formation.
Andrea Giammarino, Chiara Lambona, Alessia Raucci, Giovanna Simonetti, Salvatore Macrì, Angela Iuzzolino, Daniela Trisciuoglio, Sergio Valente, Gustavo Giusiano, Letizia Angiolella, Antonello Mai   +10 more
wiley   +1 more source

Candida albicans and Candida dubliniensis Show Different Trailing Effect Patterns When Exposed to Echinocandins and Azoles [PDF]

, 2020
International audienceWhen Candida albicans and Candida dubliniensis isolates were tested for susceptibility to fluconazole and echinocandins using either EUCAST or Etest methods, differential patterns of growth were observed, independently of the ...
Dannaoui, Eric, Ayadi, Rania, D'Enfert, Christophe, Bougnoux, Marie-Elisabeth, Sitterlé, Emilie   +4 more
core   +1 more source