Results 51 to 60 of about 13,317 (169)
FEBS Letters, Volume 600, Issue 17, Page 2579-2614, September 2026.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Advanced Science, Volume 13, Issue 53, 24 September 2026.Caspofungin heteroresistance is prevalent in clinical Candida glabrata isolates and depends on calcineurin‐mediated stress adaptation. This transient phenotype serves as a reservoir for resistance evolution, enabling the emergence of stable resistant descendants under prolonged drug pressure.
Yanyu Su +7 more
wiley +1 more source
Successful management of recalcitrant fungal keratitis with topical caspofungin
GMS Ophthalmology Cases, 2022 Objective: To report a case of recalcitrant fungal keratitis successfully managed with topical caspofungin acetate in North India.Methods: Case report and literature review.Results: An 18-year-old male patient presented with complaints of redness ...
Goel, Siddhi +2 more
doaj +1 more source
, 2022 Echinocandin antifungal drugs have a broad spectrum of activities and excellent safety profiles. These agents noncompetitively inhibit the formation of the major polysaccharide component of the fungal cell wall, a reaction catalyzed by the membrane-bound
Micha Fridman +7 more
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Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden
ChemFoodChem, Volume 2, Issue 3, September 2026.ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley +1 more source
Impact of special patient populations on the pharmacokinetics of echinocandins [PDF]
, 2015 Contains fulltext : 153098.pdf (Publisher’s version ) (Open Access)Echinocandins belong to the class of antifungal agents. Currently, three echinocandin drugs are licensed for intravenous treatment of invasive fungal infections ...
Burger, D.M. +6 more
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, 2021 Invasive candidiasis is known to be one of the most common healthcare-associated complications and is caused by several Candida species. First-line drugs, particularly echinocandins, are effective, but there are increasing reports of resistance to these ...
Dafne Bongiorno +8 more
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Journal of Peptide Science, Volume 32, Issue 9, September 2026.Gold nanoparticles conjugated with a tick‐derived antimicrobial peptide, Os‐C(W5), demonstrate enhanced proteolytic stability and potent antifungal activity against Candida albicans biofilms and planktonic cells. These non‐cytotoxic nanoconjugates represent a promising biocompatible strategy for combating resistant fungal infections while maintaining ...
P. J. Palm +7 more
wiley +1 more source
A Review of Antifungals and their Mono- and Combination- therapy in the Treatment of Invasive Fungal Infections [PDF]
Journal of Kerman University of Medical Sciences, 2016 Invasive fungal infections with high mortality rate are a growing health concern in hospitals and medical centers. The infection usually occurs in people with compromised immune systems.
Amir Arastefar, Parisa Badiee
doaj
Antifungal treatment with echinocandins: a 10-year clinical experience [PDF]
, 2017 Producción CientíficaIntroduction: The number of studies evaluating the use of echinocandins, whether or not its indication meets international guidelines, in clinical practice is limited.
Heredia Rodríguez, María +11 more
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