Challenges in optimizing tacrolimus therapy in patients treated with rifampin: A case series
British Journal of Clinical Pharmacology, EarlyView.Tacrolimus is a cornerstone immunosuppressant in transplantation medicine with a narrow therapeutic window. Drug–drug interactions with strong CYP3A4 and P‐glycoprotein modulators, such as rifampin and azole antifungals, significantly alter tacrolimus exposure and complicate therapy. Two transplant cases illustrates the impact of rifampin on tacrolimus
Jeroen P. A. Houwen +6 more
wiley +1 more source
Development of a novel family of antifungal agents based on a quinone methide oxime framework. [PDF]
Sci RepJaneczko M +14 more
europepmc +1 more source
Fungal Diseases in Elasmobranchs and Their Possible Treatment with a Special Mention to Azole Antifungal Agents. [PDF]
Animals (Basel), 2023 Cañizares-Cooz D +5 more
europepmc +1 more source
Cytochrome P-450 as a target of azole antifungal agents.
, 1987 Yuzou YOSHIDA
openalex +2 more sources
In-vitro activity of voriconazole (UK-109,496), LY303366 and other antifungal agents against oral Candida spp. isolates from HIV-infected patients [PDF]
, 1999 Mónica Chávez +5 more
openalex +1 more source
Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application
BMEMat, EarlyView.The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah +9 more
wiley +1 more source
Synthesis, characterization and bio-evaluation of novel series of pyrazoline derivatives as potential antifungal agents. [PDF]
Sci RepYadav CS +11 more
europepmc +1 more source
Restricticin, a novel glycine-containing antifungal agent.
, 1991 Robert E. Schwartz +15 more
openalex +2 more sources
Study of the Effective Dose of a Topical Antifungal Agent, Omoconazole Nitrate, on the Basis of Percutaneous Pharmacokinetics in Guinea-pigs and Mice [PDF]
, 1997 Terushi Hashiguchi +4 more
openalex +1 more source